what we found was that they had developed a competely orthoginal, sort of different system to sense problems at dna recommendation forks and transmit that into information. so what i discovered were the genes and the pathway in human cells, eventually, starting in yeast, but that actually are scouring your genome looking for problems and when they find the problem they set up a signaling apparatus that's sort of like sending out radio signals to the ambulances that come in to try to deal with these problems. as evelyn had discussed earlier, u.v. light makes a specific type of damage and there is a specific type of pathway that can snip it out and fill it in like a pothole and move on, excision repair. but if you have a problem that's in the process of duplicating the dna, and that means you're taking the dna apart and copying it, that's a much more severe problem, and when that kind of a problem happens, you need a very sophisticated response. so the response that i found was sort of the equivalent of the response in bacteria which we know existed at the time, and that turns out to alert and