[laughter] so, again, craig thompson said you can think about a multicellular or nhl, it's almost likeent to eat only when they're told to eat. it's kind of a remarkable thing because all our cells have the ability to take up nutrients, but they don't. and we have this food distribution system which is regulated by hormones. and, you know, first and foremost, the hormone insulin which sort of tells which cells to take up nutrients and how to store them as fuel in our body. so to understand cancer as, you know, this permutation of overeating glucose, you have this question, well, what makes our cells take up glucose. and first and foremost, it's this hormone insulin. so if a cell is overeating glucose, you have that. the cell has too much insulin could that be a part of this story. could that be driving this, you know, what they call the warburg effect, the warburg metabolism. and sure enough, there is a remarkable body of evidence that insulin is plague a huge role in human -- playing a huge role in human cancers. it's a growth hormone that tells cells to eat and to divide and grow. an