the crum, how common are these medications? >> these medicines are commonly used and having people on multiple medications at the same time is common. particularly when adults are 65 and older. the average prescriptions is 23. >> 23 different prescriptions per person. >> per year. >> after 65. >> on average. and you can imagine with that many drugs being prescribed, plus over the counter medications, the possibility is high. and every year, we have almost 1 and a half million hospitalized, and 100,000 deaths per year, so this is a very very serious health problem. >> dr. alexander, any chance that the more the risk goes up and the drugs you're on, the more likely an adverse effect? >> well, there's no question that as the number of medicines increases, the potential for disease interactions and drug interactions increases exponentially. when you realize that one-third of seniors are on five or more, when you consider all of the combinations of drug interactions or drug-disease interactions we're talking about substantial number