or cystic fibrosis is recessive, or diabetes or many, and it takes up to 20 generations for recessive mutations to express themselves. so we're talking about eons of time for expression of genetic disease--that's the second thing. the third thing is if the man's got plutonium in his testicles--and every male in the northern hemisphere has a tiny load in his gonad--it's from weapons testing days, and plutonium is still falling out. and the man is cremated, the smoke goes up the chimney with the plutonium, so you can breathe it in, another man can, and it's ad infinitum because plutonium has a half-life of 24,400 years and lasts for a long time. but the other thing is that the body thinks plutonium is iron--it's an iron analogue--so it's stored in the liver, where it causes liver cancer. it's stored in the bone marrow to cause--to produce hemoglobin in the red blood cells, but it causes leukemia or bone cancer. it crosses the placenta into the developing embryo--which lets nothing through it, incidentally, except plutonium and a few other nasties. it's stored in the testicle, too. so it

his 12-year-old granddaughter has cystic fibrosis. several businesses have made do imaginations.runs 20 miles a day. he expects his whole journey will take 14 months and he's hoping to raise $500,000. >> wow, and document it for him social media involved? >> there is some of that, and people in teach review he goes are helping him to run. >> good to see you. welcome back. you were missed. >> reporter: thank you, i missed you, too. >> what a story here. a nine-year-old girl kills her gun instructor with an automatic uzi, and that girl was at the gun range with her parents. we'll look at what the laws are in that situations and whether there should be stricter regulations. >> new orleans is dealing with an guns and crimes. how is the city responding to the rise in violence there? >> reporter: well, tony, right now there is some 50 additional state troopers. how long they'll be here. how long they'll stay remains to be scene. this is not just a neighborhood issue where a few neighborhoods were having problems. it's become a citywide issue. you're familiar with bourbon street. famed

his 12-year-old granddaughter has cystic fibrosis. several businesses have made donations. he runs 20 miles a day and he's been on the road for 80 days. he expects the journey will take 14 months. he has had support from so many local. >> it's he has to be doing social campaign. >> he has facebook page and you can call it the social media. >> are you back later? >> i am. >> thank you. people who live near a massive oil stands deposit in canada are worried about a cancer cluster in their community. we have reports from fort chiperyan. in alberta. >> one of dozens to contract cancer in recent years. breast cancer in her case. now she's in remission but some of her friends haven't been so lucky. she and others are worried that their beloved hometown is a cancer hot spot. >> we live here, and we see our neighbors, our friends being diagnosed. i think in the back of our minds we sort of say, i wonder who is next. >> at the local clinic nursing staff say most of their patients live in fear of their health. >> x-rays, ct scan, mri. they want all those tests to be done just to be o

we are already doing selection to avoid cystic fibrosis.f you had the capability of altering genetics, there are 60% to 70% of people who say they would enhance the physicality of children if they could with genetic engineering. so this is where this is going. of course there is a lot of angst with it. but the idea that we can stop is absurd. it's not like there is one little technology that is causing all of these weird things. this is happening across a broad technology front. it is not one genie who needed help out of a bottle. it is hundreds everyday. look at the way the internet is going. this is big stuff that is happening and here is what is really going on. this was 2500 years ago. he said, -- that is really the charge that we have to take for us and our children. how do we deal with these incredibly challenging and difficult technologies that are really altering our sense of who we are and what we are and what life is all about. that is where the situation is heading. [applause] >> i would like to give each speaker an opportunity t

but he has cystic fibrosis. a life threatening lung and digestive disease.is airway. and medication before eating anything. >> i have to do these therapies. i have to take my medication every day if i want to survivor. >> gunner was diagnosed at two. >> when you get that news you think the worst. >> boomer was just traded to the jets. he realized that football gave him a national platform. >> figuring i'm in the media capital of the world and how i could use that to leverage who i am to raise money and awareness of the disease. >> that year they launched the boomer esiason foundation. >> we support hospital development. >> in two decades they have raised more than $100 million. >> it's not easy. it's pain staking and time consuming. but sitting next to me i have a passion for it. where the reward was that what if tnew car smelledit card and the freedom of the open road? a card that gave you that "i'm 16 and just got my first car" feeling. presenting the buypower card from capital one. redeem earnings toward part or even all of a new chevrolet, buick, gmc or

we are already doing selection to avoid cystic fibrosis. if you could act to late -- if you had the capability of altering genetics, there are 60% to 70% of people who say they would enhance the physicality of children if they could with genetic engineering. so this is where this is going. of course there is a lot of angst with it. but the idea that we can stop is absurd. it's not like there is one little technology that is causing all of these weird things. this is happening across a broad technology front. it is not one genie who needed help out of a bottle. it is hundreds everyday. look at the way the internet is going. this is big stuff that is happening and here is what is really going on. years ago.00 said, -- that is really the charge that we have to take for us and our children. how do we deal with these incredibly challenging and difficult technologies that are really altering our sense of who we are and what we are and what life is all about. that is where the situation is heading. [applause] >> i would like to give each speaker a

groups that have done that like cyst stick f cystic fibrosis, that's why they succeeded in getting the products on to the market because they have the patients ready and they have genotype. and i'm very interesting in the drug manufacturing. there's a lot of innovation in drug manufacturing. we're having a big meeting in a few weeks about this. right now we have drug shortages that are afflicting the hospitals across this country. we are buy many of our drugs from other countries. and if something would happen, won't be able to get the drugs anymore. hostilities, natural disaster, whatever. and thirdly, that's another thing faced by developers. they have to continue to try to scale up their manufacturing and it's very much like the clinical trial system. very outdated. very cumbersome. there's now the technologies available to do these continuous manufacturing and make things that could be made in the united states. they wouldn't have to be all over the place. it's environmentally friendly and it's the wave of the future and how drugs should be made. where they're needed. so i think th

the cystic fibrosis foundation was noted and the prostate cancer foundation. the melanoma research alliance is out there. a multitude of these groups. what i think the system can learn from these groups and what we have studied is that they are one-stop-shopping in terms of understanding what science do we know and what don't we know and what do we need to be getting prepared for. where's the puck going to go? and how do you bring the patient into the center of all of that? so a couple of points that i wanted to make sure i talked about at the topline is the sacredness of this 'innovation ecosystem and the real need for that stability to come and then the putting the patient at the center of it. i want to mack sure that as you do your work, we're making sure that happens. thank you. >> first of all, i want to thank you for convening this important committee and i want to thank congress for their work. actually, recently, through the reauthorization of the user fee act we had -- [ audio difficulty ] >> i'm trying. we had a mechanism that was sponsored by friend