right now we talk about david kesler. why do we look and feel in ways that we do not. >> blows help me give a warm welcome to doctor david kesler. >> stharng you, and thanks to book passage, one of our favorite bookstores and thank you all for coming out. >> the journey that led to capture, began about 25 years ago for me, at f.d.a. we began the investigation into the tobacco, and, i became interested why one would smoke one and then, 780,000 more over a lifetime. and then i became very interested in overeating and trying to understand why that chocolate-chip cookie has such power over me. the mechanism in both seemed to me to be somewhat similar. a stimulus, highjacks our attention, based on past learning, there's this arouse sal, increased attention. these thoughts of wanting, and i eat the cookie, and i have this momentary bliss and two minutes later i go why did i do that? and the next time i'm exposed to some cue associated with it. i do it again. i strengthen those circuits. so i had to learn everything i could abou