salon.com founder, david talbot a perspective on what makes san francisco and the entire region special. a critical look at what needs to be done to continue to attract money, resources, and above all, talent to our medical research institutions, the chancellor of uc san francisco, sue desmond. >> leno coastland, it's great to have you onset. great to have you here. >> exciting to be here. >> what advice do you have for folks in terms of just whatever their passion is or direction, that entrepreneurial spirit that's inside all of us? >> i tell peel, if you are an entrepreneur, you have passion, go after what you are passionate about. i generally find -- and this is surprising to people entrepreneurs who chase making a buck tend not to be as successful as entrepreneurs who chase their passion. passion is a key ingredient to real success in entrepreneurship and i item people their passion is what they can get excited. when somebody goes wrong, they will bang their head against the wall instead of giving up. >> that's what entrepreneurship takes. i am a huge fan. it's patrol the only thing