doctoroff still maintains a busy, albeit scaled-back, schedule.spa motorbike around his upper west side neighborhood to meetings. but most of his effort is focused on target als, his nonprofit raising money for als research. doctoroff founded the organization in 2013, long before his own diagnosis, but after his father, and then his uncle both died of als. >> my most important legacy will be making a contribution to eradicating als because it is so personal. one in 400 people are going to get the disease if we don't find treatments. judy: two years ago, he set a fundraising goal of 250 million dollars, which at the time of our interview was more than 90% complete. much of the current cutting edge research on als happens here at johns hopkins university in baltimore, at a center run by dr. jeffrey rothstein. rothstein himself diagnosed doctoroff, and works with hundreds of men and women who have the disease. >> als patients are america. there's a full range of what i see in my clinic, from top athletes to brilliant attorneys to couch potatoes. when