dr. annie sparrow, deputy director of the human rights director at mount sinai hospital in new york, and geneva, switzerland, the doctor who leads the team studying answered microbial resistence. let's go back to when these drugs were first introduced. was it always understood that this was a threat waiting out in the wings that some day resistence was going to be a problem? >> yes, indeed, from the very beginning. we have been alerted, the one discovering penicillin, and he, at his noble prize speech he already alerted the world that resistence to antibiotics would arise. once we start using these precious drugs the more we use, the faster they would become ineffective against the bacterial infections. >> was there a threshold that was crossed to get the who so concentrated on this problem. with my kids, our pediatrician would say we're not using this drug or that drug with things like ire infections. my kids are fine today. what is it that is now making this something that the world should be more concerned about? >> well, as you have said we have reached the point where we are facing