dr. cantillon -- first thing you for your comments. i was told the comments he made before and i deeply appreciate you saying that. the critical path initiative is certainly something near and dear to my heart. i strongly support the public-private partnerships and am pleased to learn this program has been very effective in tackling diseases dislike alzheimer's, and you mentioned in your testimony that one way the congress can be helpful is to provide the resources to increasing the staffing levels of the fda and as i mentioned before i could not agree more. we need to increase resources to the fda to bring the new drugs to market but given the limited resources we are working with i was wondering if you could address other ways we might help break down the barriers to translation research and help fill in the gap that opened up between biomedical researchers d the patient who need their discoveries which we unfortunately referred to as the value of death. >> thank you for your partnership. i think the public-private partnerships are c