hamburg: >> not always because -- senator cassidy: >> so, if not -- dr. hamburg: >> we were talking about the user fees before. senator cassidy: i just have limited time. let me go back to my point because i have a question for dr. collins. if you can make that information more available, i think that would help us as we looked on a granular level because that is our responsibility to provide the oversight. senator cassidy: just one point there. the user fees are often targeted to specific programs through a negotiation programs, so they -- the programs with user fees have a bit more flexibility, and hopefully more predictability, in terms of resources. i'm a doc and apparently dr. that doesn't want a gastroenterologist taking care of his cough. that said -- clearly, our goal is transitional research correct? dr. collins: yes. senator cassidy: now, some of your mds and some go to phd's. do you track what percent of the grants go on to ph.d.s and those which go to mds result in transitional research? is there a difference? dr. collins: >> we do track that.

senator cassidy. >> dr. hamburg, one, great job. my picture you done remarkable progress so thank you for that. you recentlyyou of recently put out your fda's transparency initiative. i've tried to understand your agency but certainly don't understand the issue. there are different divisions that do different quality of work in terms of approving new applications. and intuitively there are some which have high turnover than others. i suspect those with lower turnover are the ones which have better output. now i see that as a diagnostic. frankly, i think it indicates in those divisions of high turnover and lower output there's probably some issue their that in management, leadership, you name it that is problematic. in your transparency initiative will there be more information regarding that so we and oversight can look at that on a granular level trying to get a sense how your successor could perhaps improve those processes? >> certainly the transparency initiative was a multifaceted undertaking intended to both to expand understan

dr. cassidy says the trajectory is frightening it will bankrupt the health care system and is causing suffering for the victims and their families. i know you mentioned new treatments and i am excited bush shouldn't we do more targeted items to alzheimer's? >> i share the concern if you look at the cost of alzheimer's in in the cost of individuals afflicted not to mention the suffering that they go through we're on a trajectory anybody should be deeply concerned. we certainly are ramping of research at a pretty unprecedented rate between 2011 and the budgets present budget proposal for 2013 greater than any other area that nih supports it is not enough frankly we don't have enough to support all the other ideas but the good news is that research is in a very exciting place. we do have to reduce with therapeutics in the ability to do drug screens on cells that represent alzheimer's and the way we could not have dreamed you to believe figure out how to address those therapeutics with a lot of excitement to see that go for word pro but to be sure we're building on the capabilities of other agencie

dr. cassidy says. the trajectory is frightening. it is going to bankrupt our health care system and it is also causing such suffering for the victims and their families. i know you mentioned the amp and the brain initiatives and i'm excited about those. but shouldn't we be doing even more to do a concerted effort targeted at alzheimer's given what the trajectory of this disease is? >> i appreciate the question and share the concern. when you look at the cost of alzheimer's disease and the care of individuals affected, not to mention the suffering their families go through, we are on a trajectory that anybody looks that it has to be deeply concerned about it. we are certainly ramping up research at a pretty unprecedented rate. between 2011 and the president's proposal for 2016, there will be a 42% increase for alzheimer's research, greater than any other area that nih supports. is it enough? no. frankly, we don't have enough that i could argue to support all the ideas and lots of other areas. the good news is that alzheimer's disease

dr. cassidy says. the trajectory is frighteninging, it's going to bankrupt our health care system and it's causing such suffering for the victims and their families. i know you mentioned the amp and the brain initiatives and i'm excited about those. but shouldn't we be doing even more to do a concerted effort targeted attal simers given the trajectory? >> i appreciate the question and share the concern when you look at the cost and care of individuals afflicted, not to mention the suffering their families duothrough, that swrid go through. we are on a trajectory that anybody has to be deeply concerned about. we are certainly ramped up research at a pretty unprecedented rate. between 2011 and the president's proposal for 2016, there will be a 46% increase for research, greater than any other area nih supports. is it enough? no. frankly, we don't have enough that i could argue to support all the ideas and lots of other areas. the good news is that research is in a very exciting place. that we do have new

dr. bill cassidy joining us today from capitol hill.ning the case. >>> heather nauert is here with more on what's happening. >> hi listen to this story. this is going to have a lot of moms upset this morning. there is a mother who is outraged after her six-year-old son is force today walk half a mile in knee deep snow through busy traffic. after a bus driver dropped him off at the wrong stop and then wouldn't let the kid back on that bus. he was on a bus with a substitute driver. this happening in indianapolis, where they've had terrible weather lately. when they reached the last stop the driver made him get off that bus anyway. >> i just saw him run around the corner with snow up to his knees, his face was red and he was crying. i'm like what happened? he said the bus driver dropped me off at the wrong stop and he wouldn't listen to me when i told him i didn't live there. >> officials say they are concerned about this and are investigating the incident. >>> a manhunt is on now for two armed men robbing a pizza hut in miami. they jumped