dr. david maloney and i are excited to be here for an important announcement. i'll start with what david alluded to, which is the fred hutch has been in existence for about 41 years. it's the place where bone marrow transplantation was invented by dr. don thomas. he went on to win the nobel prize for that work where patients with leukemias are treated with chemotherapy and radiation. such high doses they would die from that treatment meant to rad kate the leukemia. what we didn't appreciate at the time but came to an understanding of is that it was the donor's immune system that was so critical and the cure for potential of bone marrow transplantation. we didn't understand how that worked at the time, this was decades ago. over the years, we and others have a deep and broad understanding of how our immune system works around the mechanisms that activate the immune system and turn the immune system off. tumors have a way of turning the immune system down and that by understanding those mechanisms, we can develop novel approaches that harness the extraordinary pow

dr. gilliland? thank you very much, david, for that fantastic introduction. i think you covered most of my talking points. but i am gary gilleland, the president and director of the fred hutch -- my colleague, dr. david maloney and i, are delighted to be at the national press club for an important announcement. and i will start with what david alluded to, which is that the fred hutch has been in existence for about 41 years. it is a place where bone marrow transportation was invented by dr. don thomas. dr. thomas went on to win the nobel prize for that work, in which patients with lethal forms of cancer -- leukemia -- are treated with chemotherapy and radiation therapy, such high doses that they would die from that treatment, meant to eradicate their leukemia, were they not to have donor bone marrow infused to rescue them from the effects of the chemotherapy. what we did not appreciate at the time but gained an understanding of is that it was the donor's immune system that was so critical in the curative potential for bone marrow transportation. -- transplantation. we did not understand how that worked at the time. this was decades ago. over the years, we and others have a deep and broad understanding of how

dr. david maloney and i are absolutely delighted to be here at the national press club for an important announcementand i will start with what david alluded to which is the fred hutch has been in existence for 41 years. it is the place where bone marrow transplantation was invented by dr. don thomas. dr. thomas went on to win the nobel prize for the work. which patients with lethal form of canners are treated with radiation therapy and chemotherapy, such high doses they would die from treatments to eradicate if they did not have bone narrow infused to rescue from the chemotherapy. what we didn't appreciate at the time but gain ad understanding of, it was donor's immune system was so critical in the curative potential for bone marrow transplantation. we didn't understand how that worked at the time. this was decades ago but over the years we and others have a deep and broad understanding of how our immune system works around the mechanisms that activate a immune system and turn the immune system off. tumors have a way of turning immune system down, bid thatting the mechanisms we develop novel therape

dr. david maloney is an oncology. leading a clinical trial that is