dr. glaspy: they probably should avoid secondhand smoke to the extent possible. and then i think their dietary manipulations ought to be aimed at the prevention of heart disease for a little while longer because we understand how that works. heart disease is a more common disease than cancer and it makes more sense to focus your diet there. probably when the dust settles, those diets are going to be the ones that turn out to lower cancer risks as well. dr. bernstein: i would probably suggest getting lots of exercise... or making exercise a regular lifestyle habit, because there are certain cancers where we know that the exercise reduces your risk. exercise does definitely reduce your risk of colon cancer. we see it in studies of men. we see it in studies of women. i think obesity is related to risk of several cancers so people who are extremely heavy have higher risk of certain cancers. i want to mention that i'm very excited about the potential that we're on the brink of having medications that dramatically lower cancer risks. and i would predict that in the nex

dr. glaspy: the angiogenesis-inhibiting drugs... there are a lot of them out there. some of them have exciting pre-clinical data. they're in early clinical trials, and they may sort of change this gameboard a lot for us. then we... get into the realm of experimental treatments, drugs like herceptin, which... attack something that's different about a cancer cell, and make that cell either stop growing, or make it more sensitive to treatment with the other modalities. in 1986, the scientific community learned that a gene involved in regulating cell growth had been discovered -- her2/neu. about the same time, dr. dennis slamon and his team of researchers were extraing dna from discarded cancer tissue, looking for genetic alterations that might be linked to the disease. these are the pieces of the breast tumors. dr. slamon: about 30% of patients who had breast cancer had this particular gene altered, and we recognized that it wasn't something inherited, but it was something that was occurring during the life of the individuals. in a normal cell, they conol the production