david: you joined eli lilly when?> i followed my girlfriend, now my wife, who was going to school in indiana. back to indiana. i needed something to do there. i decided to enroll in the m.b.a. program. medicine is a four-year degree, m.b.a. is two, i still needed something to do in indiana so i joined lilly. david: what was your position in the beginning? >> i was in the department that looked at m&a transactions. and the finance and business development group. great introduction. david: did you ever say i'm going to be the c.e.o. someday? >> not then. i was thinking i'll be here for two years and then off to chicago or san francisco and do something different. but i fell in love with the company. i mean, it's an amazing place. it's a very humanistic culture. but yet very rigorous and scientific. so it's demanding, smart people but people are nice to each other. it's the midwest. and i fell in love with the mission. what could be better than making medicine for people? i worked on a medicine to collaborate and bring i

eli lilly is the top pick.d you are seeing over the next five years, $175 billion of revenue will basically fall off the patent cliff. what does that mean for the verall industry and what companies are the most exposed to that and least exposed to that >> frank, obviously, as you know, patents are at the center of the development and innovation in the sector drug companies have patents with the drugs. the patents expire typically after 20 years companies have to continually innovate to continue to drive new innovation and outer year revenue growth they have $175 billion rolling off by the end of the decade how do companies navigate that period of time pipelines and product cycles are the life blood of the sector we talked about in eli lilly with zepbound is the key piece of innovation. the other is external innovation they look through business development and m&a to bring in additional drugs to drive revenue growth and innovation. those are the two ways we continue to see the industry being able to navigate th

one of the leading manufacturers of those is eli lilly. it has transformed itself over the last five years to a company that is now one of the most valuable pharmaceutical companies in the world. i sat down with dave ricks to talk about this anti-obesity phenomenon and how it's transforming america. let's talk about the phenomenon that's changed the world to some extent, which is the anti-obesity drug. now make sure everybody is on the same page, what is the name of your anti-obesity drug. dave: so the name is zepbound. the active ingredient is called tirzapetide. david: who comes up with these names? where do you get these names? dave: not me, david. we can't have names too close to each other because doctors make prescribing errors. we can't have names that make claims about what the drugs do, and can't have drugs that are only good in english. so we end up with strange names. david: was that the intention when the drug was being developed? dave: pretty early on. we launched the first gp-1 medication in the world in 2005. it was a twice

let's bring in eli lilly ceo david ricks at the healthcare conference.> good morning. >> let me express condolences about the loss of your father. >> thank you so much. >> we are stunned as usual about the fact that the stock is down. and i don't want to be too pedestrian to talk about the stock because i think you are talking about something bigger than stock. talking about something in 2025 that would be the most shocking, fastest growing drug of all time. why don't you talk about it? >> today we are putting out guidance for the year and we are excited how 25 is setting up. we exited with the business as you are referring to zepbound, mounjaro and the older one, annualizing $25 billion a your, growing 60%. that sets up a year where we are projecting for the company 32% total growth. that is about what we did last year but on a higher basis. the rest of the portfolio is doing incredibly well as well. high team growth annualizing to $20 billion. really excited about the progress of the company and 2025 is looking even brighter. >> looking even brighter b

eli lilly has a land grab for the space, and the space of disease effects of obesity. we have talked about watching closely lilly trials in other indications. that puts them, again in this great position of being part of eliminating chronic disease. think about going from chronic to curative, and when you look at the lilly pipeline, that's what it speaks to. >> dr. patel, great to see you. have a deteriorate great weeken >>> a few days before president-elect trump is sworn into office. he has promised to make crypto a priority, bitcoin trading over 100 k. mackenzie gonzalez joins us now. they're celebrating in washington. they're going to have a crypto ball, a party for donald trump. bitcoin has run so much. what are we expecting in the first 100 days from the trump administration in terms of the bitcoin. >> the first crypto ball is tonight. it's closed to the press. there are multiple reports that we're going to see an executive order that's crypto specific on day one in office. i have been talking to a lot of industry specialists who have been putting together a plan

access i think we will show eli lilly phase 3 data queue. that will be one of the biggest breakthroughs of 2025 in the drug industry. our data will come out of the end of the year and are accessed two study will allow us to go up in dose to see if we can have even better efficacy. we already believe we have the safest oral glp1 today. katie: are you in talks with bigger companies about partnering for a phase three trial? ray: our motivation over the kitchen sink is making medication accessible to all. we started the company to make medications more available. these injectables are a breakthrough but in 2023. 46% of people in the u.s. are obese. globally it is 1.5 billion people by 2030. the numbers are astounding. oral pills are the solution. by having our data readout progressing, continuing to talk with partners, to your question, we will continue the dialogue's. our goal, getting the medicines to all. we believe we need a strategic partner for commercialization. sonali: keep us updated on that front. i'm curious. what are the big topics h

we know eli lilly can be a competitor, so this is a crucial time we have to make investment decisionshen you're priced so high and you're having more cash coming in. is that how you are viewing it? lars: yes, to put a bit more color around it, the same forecast predicts that there will be one billion people living with obesity in 2035. we are serving one or 2 million of those today. so there is a huge market and there is a place for more. and then you are right that in most markets when you get more competition, and also over time, pricing moves down because you start treating those who accept the higher price point. over time you get broader access and you get patients paying a lower price. you just take our leading diabetes product in the u.s. since launch. in 2018, the price we get after we base discounts etc. is some 40% lower than when we launched. that's often not mentioned in the political debate. instead, the list price is mentioned. which is what we book in our account after the rebates. francine: the u.s. is a large market. do list or change or add quarters? lars: that's unl

we know of eli lilly. we know amgen could be a competitor.nd so this is, i guess, the crucial time when you have to make investment decisions, when prices are high and you have more cash coming in. is that how you view it? lars: yes. to put a bit of color around it, the same forecast predicts that there will be, say, a billion people living with obesity in 2030, 2035. we are perhaps serving one million or two million of those today. so, there is a huge market opportunity, and there is a place for more. and then, you're right, that in most markets when you get more competition, and also over time, pricing moves down, because you start treating those who accept, say, the higher price point -- in the u.s., that's commercial insurance -- and then, over time, you get broader access, and you get patients paying a lower price. so if you just take our leading diabetes product in the u.s., since launch in 2018, the price we get after rebates, discounts, etc. is some 40% lower than when we launched. that's often not mentioned in, say, the political deb

the idea of losing share to eli lilly is overton. valuation is low with the huge penetration growth story in america in particular and health insurance in europe will start covering this as well. super exciting. >> i guess they are trying to see if there are any other areas to advance via the glp-1 drugs. thank you for your time. the head of equities at fulcrum asset management. >>> meanwhile, russian gas ex-ex- s to europe via ukraine have stopped. marking an end to the decades long agreement. let's get a check of ttf prices have moved so far. we are trading at just -- let me check. almost .50% lower at the moment. indeed, this moves we have seen today have somewhat been controlled in the fact that we were already expecting this agreement to come to an end. so, no surprise there, however, the important development to keep in mind. let's also get a check of european energy terms firms ande have moved there. bp and totalenergies and engie moving higher on the first trading day in 2025. an important development from a political point o

your weight with a formula from eli lilly.see if you qualify at koco-tv. >> cnn presents hbo's real time with bill maher tonight at eight on cnn. >> closed captioning brought to you by mess. book.com. >> if you or a loved one have mesothelioma, we'll send you a free book to answer questions you may have. call now and we'll come to you. >> 808 two one 4000. >> busses carrying palestinian prisoners have just arrived in the west bank. the prisoners are part of the first phase of the ceasefire and hostage deal between israel and hamas. >> today, four israeli female hostages were freed. the idf says they're now in israel. let's go now to cnn's nada bashir. she's outside of ofer prison in west bank. what's happening where you are? >> well. >> actually. >> victor, we've moved away from the ofer prison now because the busses have left the prison and they have moved onwards into beitunia in the occupied west bank. we're just behind one of the busses. there are three that have been released from the prison today, carrying those palestin

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>> eli lilly is way over you i that final stretch, see what stocks do, see you at 3:00. >>> thank you very much, scott. welcome to the exchange. i'm kelly evans. here's what's ahead, stocks are weaker today. our guest said there's a different crisis, the market is underpricing. . the news from president trump he'll be creating an external federal revenue service, the s&p is up.5% since the election. plus, tiktok denying a report it's weighing a report to elon musk. the most likely path forward. >>> the sectors, strategist coming out top this earnings season. dom chu has the very latest. >> that's right, kelly a very symmetrical market. especially for the s&p 500 on a broader large-cap basis. at 5824, down 11 points, now at the highest of the session we were up roughly 35 points and down 31 points at the low, so, again, fairly symmetrical. we're tilting to the negative side today. 5824 is the level you want to watch, that 100-day more medium to longer term average price for the s&p 500, on a rolling basis. the dow industrials, just about flat on the session right now the nasdaq composi

eli lilly seeing their worst day since 2021. if the air can even come out of this big trade, what does it mean for the other big winner, a.i.? >>> and we may be on the verge of a shutdown. we dive into the details coming up. plus, getting ready, more on deck tomorrow. quantum computing stocks go higher. and two more trader acronyms. one of our traders came out not just with one of their picks but a full definition. i'm alyssa lee. steve grasso, dan nathan, guy adami and julie diehl. eli lilling sinking 6 1/2%, its worst since 1991. the move coming after disappointing zepbound and jaro. novo nordisk, trading at august 2023 lows. it's lost nearly half of its value since late june. >>> and viking thera sank. that is currently in midstage trials. for more on all of this, angelica peebles joins us. angelica? >> a, mel. that's right. lilly's fourth quarter coming up short of expectations. and that is renewing fears that it might also be slowing. >> because of supply tight accident in the first half of the year, inventory levels rose b

lose 15% of your weight with the formula from eli lilly.f you qualify at irokotv. >> so are you guys still. >> thinking about going to italy? >> yeah, just booked the flights. >> great. you guys are going to. >> love it. we went last year and it was. >> just so beautiful. >> frank. >> frank! you okay? bud? >> this is the best steak i've ever had, right? >> and i get them every month. >> nothing compares to the taste. >> of omaha steaks, guaranteed. save $30 on our. >> new usda. >> certified tender filet mignon with promo code taste 30 at checkout. >> i recently helped a couple buy their. >> dream home even. >> before selling. >> their current. >> one home. >> lights fi before. >> you sell program was. >> a game changer. >> they were able to buy. >> and sell on their own schedule. schedule. >> it was ehh... hmm. oh, that's very, uh... - right? - mmm... this store doesn't have agentforce, so an ai agent didn't tip off the stylist as to what i might actually wear. - yes. - oh. that's a commitment. [glass knocked] hey bud! whaddaya think? you k

do i sell it or hang on to eli lilly?m is people are saying after a year people are no longer taking the drugs, they are going off it, use percentage off it. i think if you own it because it's about cardiac instances, it's about high blood pressure, it's about dementia, maybe even about cancer, not just weight and diabetes, so i think you hold on to eli lilly. continue to hold for the trust. i think there will be good numbers. that last quarter wasn't good. i understand the trepidation about the stock. i still like it. nick in florida. >> caller: big booyah from florida and a happy new year to you, man. >> thank you. same to you. >> caller: my girlfriend diana, jim, this stock is down 26% in the past six months and has been a staple in my portfolio a few years now. my question to you is buy, sell or hold? kicker symbol nue, new core. >> i thought it was bottoming. this great steelmaker. i have to see -- the material stocks are weak. there is a lot of dumping of steel from china again. all they do is hack and dump and they

i think you remember about a year or so ago, eli lilly was able to bring down their cost on insulin, a lot of that was because of what this president did on capping insulin for seniors, which makes a big deal, is a life-changing effort for seniors. and so, look, not going to get ahead of any potential announcement, don't have anything to share. but lowering costs on medical prescription drugs, making sure that we make things more affordable for americans, that is something that the president has put at center when he talks about his economic policy and certainly moving forward. i don't have anything beyond that. guys, i will see you, i'll be back. reporter: -- a lot of disinformation and misinformation about response to the california fires. with the hurricanes there was some finding that chinese and other foreign countries were amplifying messages. do you have any evidence of that? karine: i don't have any evidence to share with you on that piece but what i will say about misinformation and disinformation, it is incredibly dangerous, as we all know. as we're trying to provide resour

last night i got a call from someone who complained how miserable the eli lilly stock did.they plummeted to the 7 # 0s. but i think these drugs have multiple benefits and the staying power questioned by negativists may be stronger than the krit cysts think. to me it's simple. you should buy one kind of chip that is changing the world, the semiconductors, and avoid another kind of chip, frito-lay's. we used to regard the safety stocks and semiconductors as high flyers. huge downside. now this there seems to be nothing safe about the foods but the semis, lots more staying power than anyone ever thought. i like to say there is always just for you on "mad money." i'm jim cramer. i will see you monday! returns to the tank. you're one of the most impressive people i've seen in a very long time. marcotte: this tiny object changed everything. sharks, let us break the ice. your logo is so close to scrub daddy's. i'm doing this alone. you've got to sell, man. i will never not know how to make money. that doesn't matter! i want to buy the entire company. we would take a million. bam.

. >>> we have some news about eli lilly. >> that is right.drug zepbound used for sleep apnea. remember, medicare cannot cover obesity drugs. however, it can cover the drugs when it is used for other health conditions. zepbound last month getting approval for the use of sleep apnea and now cms confirming it can be covered for that use. take a look, shares up about 2%. >> thank you for that update. now we go back to kristina partsinevelos for a look at the key factors. >> let's start with instacart. the s&p mid-cap starting next tuesday replacing this. other news for the stock, you see shares up over 5%. the delivery company is partnering with volta beauty to deliver beauty products nationwide. shares are up. they have doubled in the last year but let's talk about ulta. it is down 3%. that has more to do with the retirement of its ceo. have you noticed egg prices higher at the grocery store? maybe barely any eggs available? the supply keeps getting cut because of recent outbreaks of bird flu. it may not be helping your wallet but higher prices

stuart: now show me eli lilly, because that stock today will reflect the performance of their weights drugs zepbound in the last quarter. how did those drugs do? taylor: yeah, less than expectations is what we can say. so we're hearing they are cutting the revenue guidance to about $13.5 billion for eli lilly, so that revenue guidance includes $3.5 billion for mounjaro, but that was below expectations of what analysts wanted which was 4.4 billion in sales. zepbound came in with a view of 1.9 billion. analysts wanted 2.14 billion for zepbound, so again, weight loss drugs, you're seeing sales, but expectations have been really high for these drugs. stuart: kevin? you're a health kind of guy. you're a nut about your personal health. >> very focused on longevity. stuart: do you use? may i ask? >> i'd tell you. i have not used these yet. however, in the last couple of weeks, those of us, i have a group that's involved in very advanced longevity studies. we're looking at data about micro dosing these drugs, not for weight loss, but for longevity attributes that haven't really been pr prove

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lose 15% of your weight with a formula from eli lilly. see if you qualify at koco-tv. >> mild moderate to severe. >> crohn's symptoms. >> kept me. >> out. >> of the picture. now i have skyrizi. >> i've got. >> places to go and i'm feeling. >> free. >> controlling my crohn's means everything. >> to. >> me. >> control is everything. >> to me. and. >> now i'm back in the picture. feel significant symptom relief at four weeks with skyrizi, including less abdominal pain and fewer bowel movements. skyrizi helped visibly improve damage of the intestinal. >> lining. >> and with skyrizi, many were in remission. at 12 weeks at one year, and even at three years. don't use it for allergic. serious allergic reactions, increased infections, or lower ability to fight them may occur. before treatment, get checked for infections and tb. tell your doctor about any flu like symptoms or vaccines. liver problems leading to hospitalization may occur when treated for crohn's. now's the time to take control of your crohn's. >> control is everything. >> to me. >>

eli lilly was -- eli lilly was always a successful. in the world to have a market capitalization of $1 trillion. it's now about $900 billion or so. this is because people wanted to lose weight. roughly 70% of the people in the united states are overweight. and amazingly 40% are defined as owe bees. of -- obese. this drug tends to reduce your appetite and a beneficial impact. it seems it might also have a beneficial impact on other related problems that people have. addiction, smoking. those studies are under way. no doubt people want to lose weight and using either the ozempic or disepbound by eli lilly. lisa: how much is the optimism in the likes of eli lilly dependent on the idea of the government actually covering the cost of some these drugs at a time where that's been one of the honest contested issues in that space. david: the government has gone back and forth on this from time to time. and private insurers are covering it to some extents, not all. if you have insurance and it's covered, your costs are roughly $25 a month for ea

now that's big. formula from eli lilly.rokotv. >>> even in an amazing quarter where we had three huge live events, we had an incredible fight, two nfl games, one of our biggest tv series ever in "squid games season 2." all successful events and titles we are thrilled about. our estimates for subscriber ads driven by those titles combined represent a small minority of our total member acquisition in the quarter. so it's really the whole service that's working. >>> that was netflix co-ceo great peters on the call talking about the amazing quarter for the streaming giant and investors appear to agree, shares up double digits. >>> welcome back to "worldwide exchange." coming up this half hour we will have more on the results including the announcement of another round of price hikes. first let's get you ready for the trading day ahead. u.s. stock futures, all three indexes finishing higher on the first trading day of the second trump administration. in the green across the board, s&p up 26 points, the dow looks like it would op

your weight with the formula from eli lilly. if you qualify at irokotv. >> the trump administration continues to ramp up immigration raids this weekend, and nbc news has learned that acting deputy attorney general emily bove and trump's border czar, thomas homan, are on the ground in chicago this morning to personally observe immigration enforcement there. chicago is among the cities where immigration and customs enforcement, or ice, has increased arrests in trump's first week in office. after signing an executive order on monday, federal immigration forces now have new power to cast a wider net to track undocumented immigrants and fast track deportations. in just the past three days, more than 1400 people nationwide have been arrested and detained by ice. joining us now is nbc's gabe gutierrez in chicago. good morning. gabe, what's going on? >> hey there. >> ali, as you mentioned, we have just learned that president trump's border czar, as well as his deputy acting attorney general, are here on the ground observing those operat

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you can see faster, lose 15% of your weight with a formula from eli lilly.tv. >> with a temporary break in the santa ana winds. firefighters in california are at least now making major progress battling the ongoing fires in the los angeles area, allowing them to gain more control over some of the destructive fires that have burned more than 40,000 acres since last week. california officials say the massive palisades fire is now 22% contained, while more than half of the eaton fire is now contained. and joining us is nbc news correspondent allison barber in pasadena, just south of the eaton fire. the air looks clear. i don't know how how smoky it is still, but the winds are dying down. does it feel as though some real progress is being made? allison? >> yeah. i mean, look, the weather has been hugely helpful in a lot of ways, at least compared to what we were expecting the last couple of days. >> and you can see that reflected in the new containment numbers. right. the eaton fire, now at 55% containment, palisades fire at 22% containment. for the most part, w

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lose 15% of your weight with a formula from eli lilly. see if you qualify at irokotv. >> this show. >> is all. >> completely fake. don't get fooled and. >> everyone knows what's going. >> on. what the except ben. >> what have we done? >> the joe schmo show all new tuesdays at 9:00 on tbs. >> set your. >> dvr now. >> whirlwind week. >> so help me god. >> so help me god. >> trump takes the reins of power and unleashes a torrent of change. >> we won. but now the work begins. >> my panel will break down the avalanche of news and law and order as troops head to the border. federal agents ramp up enforcement. what to watch as trump's immigration crackdown enters week two, plus, moment of truth after hegseth squeaks through. >> its mission. no vote. how about mitch. >> mcconnell? no. >> trump's next picks take the stand. in just days. do they have what it takes? and what one legendary musician has to do with biden's last minute act of clemency inside politics the best reporting from inside the corridors of power starts now. good morning, and wel