francis collins, then head of the government's human genome project.now director of the national institutes of health. francis collins, welcome. >> nice to be with you. >> brown: so ten years later, give me an overview, how far have we come? >> we've learned a prodigious amount about our own d.n.a. instruction book, the human genome. after revealing in the draft form in 2000, getting a completed form in 2003, and then applying some of the best and brightest minds on the planet to try to figure out how it works. we know about the variation in the genome, that half a percent that makes you different from me. we've cataloged most of that. >> brown: half a percent? >> half a percent. that's all. and we've actually learned how a lot of those variations play a role in risks of disease. almost a thousand of them that you can pinpoint and say that one increases your diabetes risk. that one increases your cancer risk. the risks are modest, but those are really important insights. >> brown: let's try to break it down a little bit. you wrote in a recent article "