the french scientist fukuo at the end of the 18th century began to study the composition of gallstones, so the word cholesterol consists of the greek holly, that is bile and solid stereos since the discovery of the substance until the 1960s, there was virtually no information in evidence-based medicine about the essence of fat metabolism and a scientifically based system for the prevention of atherosclerosis. that is why, by the seventieth year of the 19th century, developed countries were literally on the verge of an atherosclerosis pandemic, for example, in the ussr and in the united states, more than a million people died every year due to this disease , this situation changed after large-scale studies in the field of human lipid metabolism after obtaining, reliable data on cholesterol, physicians began to introduce into the practice of preventive and curative medicine new information about the violation of fat metabolism. the results were not long in coming by the end of 1980 in north america, the death rate from coronary disease decreased by 60%, and myocardial infarction decrease