. >> reporter: while you may save some cash on a lower-cost ticket, gabe sagl.a says you could be sacrificing more. >> perhaps paying a little more for a fare is an investment in your experience and at the end of the day an investment in your sanity. >> reporter: as we approach memorial day, to protect yourself from a potentially frightening flight, a few tips. >> number one, be a loyal fly with that airline. number two, avoid hub to hub flights. pick your days of the week wisely. you can travel on a tuesday versus a monday? then the number of business flyers on that flight diminishes quite a bit. >>> next on "nightline," david muir on the ground in somaliland where millions are on the brink of famine. had a bad back injury, my doctor prescribed opioids which helped with the chronic pain, but backed me up big-time. tried prunes, laxatives, still constipated... had to talk to my doctor. she said, "how long you been holding this in?" (laughs) that was my movantik moment. my doctor told me that movantik is specifically designed for oic and can help you go more ofte