targeting the gene you want and only that gene.e complete monopoly on that outcome. >> we had thermofisher, thermoscientific, they told me you can't see this without -- right? i couldn't see any of it. naked eye, nothing. only really powerful kind spectrometers can see what you're doing. is that right? >> well, one of the real tools we use and they're a leader in this basis, whole genome sequencing. that's one of the reasons i can talk about it with specificity. let's take a program we're doing with biogen in the area of sickle cell. when we modify the one gene in a stem cell, we can do a whole gee gnome sequence of the stem cell and showç that it's only that single site that's being modified. so you're right, none of us can see this work. but the instrumentation like those groups are incredibly important for what we do. >> is there any disease that -- with dna, like defective dna so to speak you couldn't with this platform solve some day? >> well, ultimately, jim, i don't want to go too far off the reservation here. we're focused

>> hi, gene. on the third day of the npc, commerce minister said china has an open-minded attitude towards the u.s.-led transpacific partnership or tpp. gao told reporters that the tpp negotiations are very important and that china perceives the framework as a high-level trade pact. he also said china's keeping close contact with major countries such as the u.s., that are involved in the negotiations. but he did not say whether china would join the tpp. he reiterated, though, that the country is paying close attention to the free trade strategy. now npc delegates in the meantime have been busy discussing this year's government work report that was delivered by premier li keqiang on wednesday. it contains proposals for reforms mostly having to do with the economy. nhk world's key oak cofujita spoke to a political expert and got his take. >> the associate professor of pay king university has been studying government forums for more than 20 years. he says this year's work report puts a particularly s

you're talking about non-gene mutation where the gene is damaged but where the gene may be turned on or off. yes, there are environmental factors that will lead to this. there may be environmental factors that trip it off. we can find those out and prevent this disease. we might be able to use different things like drug or exercise or brain stimulation to actually turn it back on. gerri: amazing, amazing. i know at love families out there are desperate for some kind of a solution. what kind of proof to we have now that this might work? you. >> know i think that there's a lot of proof what we believe are risk factors for the disease, if you're unhealthy. if you have diabetes. if you have hypertension. if you had brain injury. or an athlete and had a concussion, if you have adhd as a child, these lead to risk of dementia and neurodegenerative disorders and we know what kind of triggers it. in functional neurology a lot of my colleagues are doing things with brain stimulation where we'll publish some research soon that will really show that we can change this dramatically. gerri: that's

lou: appreciate it, gene. >> thank you. lou: gene cernan. nasa scientists for the first time capturing incredible pictures, look at these pictures of an asteroid disintegrating, breaking apart. the hubble telescope photographed this asteroid located between mars and jupiter, breaking up into 10 pieces and this is lapsed photography over several months. first time such an event has ever been photographed. we're coming right back. >>> why did the woman at the center of the irs target scandal take the fifth again? congressman trey gowdy on the investigation and his legislation to slow the imperious presidency. [ female announcer ] who are we? we are thinkers. the job jugglers. the up all-nhts. and the ones who turn ideas into action. we've made our passions our life's work. we strive for the moments where we can s, "i did it!" ♪ we are entrepreneurs who started it all... with a signature. legalzoom has helped start over 1 million businesses, turning dreamers into business owners. and we're here to help start yours. turning dreamers into busines

>> yes, gene.e are seeing out here basically everywhere east of the mississippi river is dealing with some sort of severe weather today, albeit may be calmer, but very frigid off towards the north and towards the south. some warmer air, but that interaction between these two air masses, well it really has been triggering off some rough stuff. and here down towards the south we're actually seeing some strong to severe thunderstorms move across the gulf states. very gusty winds coming out of this. but the biggest threat through the next 24 hours is not so much the severe thunderstorms, it is along this warm front and what we are seeing is this precipitation come down in the form of freezing rain. back towards the south, on your -- or back towards the west on your sunday we saw numerous accidents in parts of arkansas over towards missouri. this whole system is going to continue to track off towards the east and really into the carolinas, parts of virginia, you're going to be seeing some decent ice acc

something gene simmons. >> it is gene simmons.ou know, gene simmons, is dirty, you can look at him, film thfilm -- filthy. a filthy businessman. >> you are saying because he is jewish. >> i see how it works. i see how it works. >> he took 23 years to marry the poor wife. >> he married her. when? >> on season finale. took four seasons. don't tell me i don't know my gene simmons history. how dare you think i'm any surfacey? >> a nice family. the kids go to our school. >> the kids are great. >> the kids are smart. >> the son is going to be something. >> funny, charming young man. joanne, you wear a lot of makeup. so you must have. >> all natural, come on! just kidding. off awe do you' >> what advice would you give off to the band? >> put impersonators on the stage. the cover bands. might as well. >> the little guys. little kiss. >> people want the perform ajs. i understand their maybe not wanting to do this when the band started there wasn't all this social media. everyone is a critic. everyone voices their opinions. anything they do

>> hi, gene. chinese premier li keqiang opened the annual gathering of the political elite by outlining plans for the year ahead. he addressed npc delegates announcing an economic growth target of around 7.5%. and premier li also addressed complaints about corruption, pollution, and the gap between rich and poor. delegates from across china gathered at the great hall of the people to hear the government's accomplishments, and goals for the year ahead. this is li keqiang's first time to deliver the government work report. he's officially confirmed as premier at this very event last year. >> translator: last year was the first year for our government. and its mission was difficult and heavy. >> reporter: premier li said the national government's first task was to change how things were being done. it did so by transferring more authority to other levels of government, and to the private sector. he then talked about the economy, saying maintaining a growth target of around 7.5% would build trust amon

lou: appreciate it, gene. >> thank you. lou: gene cernan.asa scientists for the first time capturing incredible pictures, look at these pictures of an asteroid disintegrating, breaking apart. the hubble telescope photographed this asteroid located between mars and jupiter, breaking up into 10 pieces and this is lapsed photography over several months. first time such an event has ever been photographed. we're coming right back. >>> why did the woman at the center of the irs target scandal take the fifth again? congressman trey gowdy on the investigation and his legislation to slow the imperious presidency. lou: we were told of a reason for obamacare is to provide health insurance for the uninsured as many as 50 million the president said in 2008 and 2009 but how many are actually citing up for obamacare? listen to the official in charge of the health care exchanges in answering the question how many enrollees were previously uninsured? >> that is not said datapoint that we are collecting in a systematic way. but probably the best way to get a

i think it is gene simmons. >> you know gene simmons, you know he is dirty. you can look at him and say he is filthy. >> are you saying -- wait. >> i see how it works. >> it took 23 years to marry that guy. >> it was on a season finale. >> the kids are great. >> the kids are really smart. the season -- the son is going to be something. >> he is a charming young man. joanne, you wear a lot of make up. >> do you have any kind -- what kind of advice would you give for this band? >> just put impersonators on stage. >> the little guys. >> people just want the performance. i understand their maybe not wanting to do this especially because when the band started there was not all of this social media and everyone is a critic and everyone voices their opinion and everything they do they get so much exposure, but in a negative way. i see they might not want to. i think that's okay. as long as they still get their award. >> andy, you have really strong feelings about this. >> why can't they all perform? throw an extra drum set up there. get them all up there. >> probabl

the other gene that we found involved is the serotonin transporter gene which is involved in personality traits like depression and impulsitivity and anxiety. people with those traits find it hard to give up smoking because they use the cigarette to self-medicate. karen miotto: because it's such a difficult addiction to recover from or to be in the process of recovery, we recommend a combination. try the patch. try an anti-depressant. make sure you go to some kind of program to get tools and techniques to identify when you're craving, when you're having high-risk situations, to help prevent the cycle of stopping and starting and stopping and starting. people really need to anticipate these risk situations and practice the behavior of declining, declining the cigarette or getting out of the situation. the individuals who simply believe they're going to proceed on willpower and don't anticipate the specific risk they're going to face and develop strategies for coping with those risks are much more vulnerable to relapse than individuals who've been through these behavioral psychosocial trea

>> hi, gene. this once a year meeting is so important here in china that people in this country categorize it as its own season, the political season. npc spokesperson spoke to reporters ahead of the opening session. she talked about president xi jinping's determination to tackle bureaucratic corruption. fu says there will be zero tolerance for corrupt officials and anyone found guilty must be harshly punished. fu dismissed worries that other nations have exposed about china's ongoing military buildup. she said china believes it can maintain peace by strength and that the chinese people can only be rest assured if they're the strong force defending their homeland and fu acknowledged environmental problems, saying pollution is a major challenge for china, and delegates at the upcoming npc. >> translator: this year we will start law enforcement on air pollution, prevention, and control. and we will revise it to provide legal guarantee in tackling smog. >> reporter: now, today, was actually a rare bl

there is large caps that are attractively valued here and we reck meant cell gene and gilliad. be cautious about the smaller cap names. >> thank you so much. >>> there is just one week left until the affordable care act's open enrollment ends, but for some states, another deadline looms leaving six months to fix problems for the web-based exchanges for 2015's open enrollment. it may be harder to fix some of those than start from scratch. >> reporter: after a notoriously bad start, kathleen sebelius is looking for a strong finish to aca open enrollment. the marketplace works well for the 36 states it serves but in about half of the states that built their own exchanges, problems persist. >> certainly have some states that get an f grade, some that are in the d category. >> reporter: among those not making the grade, hawaii, massachusetts and vermont that use cgi to build the exchanges, the same contractor for problems with healthcare.gov. the base state fired them and maryland fired its contractor the north dakota based noridian and ceo burns is grateful that the state will keep

sell gene is leading the way. it has broken trend. remarkable here is the precision of that top, the absolute mirror image of that top. the neckline, you're hovering at these lows and ultimately that is a very powerful setup for a break. the objective is this gap down here, if it continues, the biotech will finally break trend as a group. >> bad news potentially according to the charts. it was interesting because we had the letter from the democrat congressman questioning the high prices of drugs. at the same time, sell gene had approval for sore attic arthritis drug and still it's trading much lower. >> this stock is being punished and carried out on the group. there is one thing i have to say about the group. when you look at it fundamentally it's hard to argue it's expensive. i can see the trend line carter is referring to. what i think i want to do with this trade is take some of the profits, use just those profits to push basically press a bearish bet by rolling up and down a little bit. you need to take a little money because it

>>> welcome to nhk world "newsline," i'm gene otani in tokyo. here is a look at some of the stories we're following at this hour. the leader of ukraine's southern region vows to strengthen ties with russia as supporters and opponents of the interim government clash in the country. >>> politicians turn their attention to improving education for children in rural areas at the national people's congress. we have the latest from beijing. >>> and a senior u.s. official has urged china to provide more openness about its defense capabilities and intentions after beijing increased annual defense spending by more than 12%. >>> people in ukraine are divided over their country's future. supporters and opponents of the interim government scuffled during demonstrations in an eastern city and the leader of the southern region of crimea is promising more cooperation with russia. >> translator: we will maintain our strong ties with russia. >> ethic russians make up a majority of the people in crimea, the road leading to an airport near zef stoep ol has been blo

mutation and what it might mean for her daughter's health. >> we're able to identify the gene. could change her treatment strategy. >> a third of the time they're able to find a reasonable candidate. >> to learn the answer she's about to have her genome sequenced at the clinic just established at stanford hospital. a genetic counselor says purposes range from helping families manage risk to pinning down the cause of unexplained illnesses. >> when find a variant we're confident contributes to explaining the picture it's a relief and excitement and just great to provide that news to the patients. >> we're at the end of the day detectives. >> this heart specialist is the co-director and says a single blood sample starts a complex process that would have been unfathomable. first dna separated out and placed in powerful gene sequencers after results are in a team uses algorithms to hunt for variations. >> then, we look at differences. that leads to a long list of phone shall candidates >> they say the value is still being gauged. dr. ashley says participants have been children and a

mutation and what it might mean for her daughter's health. >> we're able to identify the gene. treatment strategy. >> a third of the time they're able to find a reasonable candidate. >> to learn the answer she's about to have her genome sequenced at the clinic just established at stanford hospital. a genetic counselor says purposes range from helping families manage risk to pinning down the cause of unexplained illnesses. >> when find a variant we're confident contributes to explaining the picture it's a relief and excitement and just great to provide that news to the patients. >> we're at the end of the day detectives. >> this heart specialist is the co-director and says a single blood sample starts a complex process that would have been unfathomable. first dna separated out and placed in powerful gene sequencers after results are in a team uses algorithms to hunt for variations. >> then, we look at differences. that leads to a long list of phone shall candidates >> they say the value is still being gauged. dr. ashley says participants have been children and adults with unexpl

doesn't have the very ends of the s t o team associated with the beast but they discovered three other gene variants. there is the exception of folic acid vitamin that protects the body from cardiovascular disease. it's found in green vegetables and whole grain products among other things in addition to fish but has the gene variant that contributes to increased risk of diabetes. so he should also be cautious about facts and concentrated carbohydrates. and he kept that up allies omega three fatty acids well. so he should eat more of them. for instance in the wally salt water each this month in its quite shocking to have the evidence and touch are normal metabolism isn't working the way you think it is good to continue through to singapore. the researchers themselves say that three variations from only five dakota jeans or less meaningful when it could be more than ten thousand relevant genes. so they're interested in something else windy dawn to dusk this and the opposite end of the old one turnover. i was a except the fact that we aging or typing this to what extent are they willing to mak

i don't believe gene's gun was in his hand. that's why it was moved. i don't believe gene was where you said - that's why he was moved. >> during the raid, the police found cannabis on the property and tonya's son, adrian - who holds a medical marijuana license - was arrested. he's been charged with possession with intent to supply a charge the family denies. now tonya is fighting to clear her family's name and get answers about eugene's death. >> that's him - 80th birthday party. >> he doesn't look like a dangerous man. >> anybody with authority, he was very respectful to them, praise them for doing a good job. i mean he would give them thumbs up, fire dept, sheriff's dept, pat them on the back. tell em you know what a great job, what would we do with you guys, you know? >> that's old man river >> yes (laughs) >> his clothes and his shoes, they smell like him, still in the bedroom and i don't want to move them. i know you keep taking things away and they're gone and i don't want him to be gone, sebastian! i don't want him to be gone! >> eugene's body

looked at the embryos that were in the dish, and they figured out which ones did not have the gss gene, and they discarded those embryos, and she went on to have healthy babies who would not have the disease. >> it's morally controversial to destroy an embryo, when you pick up the one that is will have a horrible disease or live a shortened life span, it seems to be the ethical thing to do to avoid creating that burden. that type of screening embryos, that use of ivf i support that. >> we have other things, breast cancer genes, increasing the likelihood of severe breast cancer. where do you draw the line? that's the big question. i'd say in? ? when you talk about a certainty of disease, you see flawed genes, you have a child with terrible conditions, rarer but dead for the baby, i think there you can screen. we get requests to say, "hey, how about boy or girl?", we don't do it at my schools, a lot of others they don't. >> some do. in india it has a big business. if it's a clear cut disease state or the rfb of a clear cut disease, you can screen morally. when it's a difference, a taste,

next speakers. >> good afternoon. >> my name is gene and i'm a rez of knolls and i want to oppose 36. i'm a former member of the 2011-12 grand jury with we talked about muni about eliminating our cutting back on switch backs and you have done that and i haven't been dumped off a bus recently so it must have been decreased. when i bought my home in the early in the 1990s knolls and i knew it was there. it comes every 30 minutes. i probably should have worked longer because i need money for taxis ever where i go. if i go to a doctors appointment or volunteer efforts. my work on the grand jury, that would have taken a lot of taxi money to get off that hill. now i'm retired and it's too late for me to work longer, so what do i do and how do i increase my income to take taxis and as you know taxis don't like to come to this neighborhood because they feel like it's out of this way. i want to thank you for listening and i hope you'll reconsider and there's lots of families and older people that are depending on your decision. thank you. >> thank you. next speaker, please. >> walter, christin

i don't believe gene's gun was in his hand. that's why it was moved. i don't believe gene was where you said - that's why he was moved. >> during the raid, the police found cannabis on the property and tonya's son, adrian - who holds a medical marijuana license - was arrested. he's been charged with possession with intent to supply a charge the family denies. now tonya is fighting to clear her family's name and get answers about eugene's death. >> that's him - 80th birthday party. >> he doesn't look like a dangerous man. >> anybody with authority, he was very respectful to them, praise them for doing a good job. i mean he would give them thumbs up, fire dept, sheriff's dept, pat them on the back. tell em you know what a great job, what would we do with you guys, you know? >> that's old man river >> yes (laughs) >> his clothes and his shoes, they smell like him, still in the bedroom and i don't want to move them. i know you keep taking things away and they're gone and i don't want him to be gone, sebastian! i don't want him to be gone! >> eugene's body

well it turns out that the same genes that control metabolism also control appetite-- these are genes coding for hormones and receptors that are released in response to how much a person eats and how fat their cells are, in essence. it turns out the same hormones and receptors control how hungry you are. so when people eat a big meal, the hormone is produced. the hormone tells the body, "burn off the fat and use it as fuel," and it also tells the brain, "you're full, stop eating." if a person has a problem or different variety of these hormone and receptor genes, then their body doesn't burn off the fat so well and they want to continue eating. so often people will say, "well, he has a metabolic problem, but she doesn't have enough willpower." actually both of those are at least, in part, affected by a person's genes. one theory is that these genes are leftover survival mechanisms from thousands of years ago, when humans lived from one meal to the next-- or one feast to the next famine. joanne ikeda, r.d.: if, when they found a lot, they ate a lot and deposited fat in the body, then w

seedsin ever genes non-gm and it could be raking in over $200 million a year in sales by 20 18.uld be much less. >> even with ever genes business, there won't be any major cops in the market with averaging in sight until 2019. >> in the meantime, it aims to start selling high-yielding by 2016.eds herbicides are also on the list. what makes the ever genes story unique is the fact that their success is not entirely contingent upon one product or even one collaborative agreement which significantly diversifies the risk. potentialooks at the commercialization of even a few of the products within a pipeline, the potential value of that emily exceeds the near and intermediate term risks. they cane convinced turn their algorithms into super corn or wheat or canola. keeping investors are it safe. perhaps even being bought. iniott gotkine, bloomberg israel. >> the pulse is coming up next. tech next.talking ♪ >> facebook gets all futuristic. it is working on drones. to deliver the web to underserved areas. >> microsoft unveils office for ipad in a mobile push. >> first he takes paris, now

the sawdust on the list of countries the gene that citizens of boston a us study has shown the findings of raising concerns of avoiding the religious intolerance in

gene, i want to talk to you about this first. this is really basic democratic talk. the only thing that really makes it different is the sort of positive morale officer role he is playing which is to say we're on the popular side of these issues. >> exactly. he's saying we're on the popular side. more people agree with us than agree with the republicans. so let's get out there. let's fight. and the rallying cry for the people assembled in that hall, the democratic national committee who are going to go out and go back to their states and work is to get the voters out. to get the democratic voters out. young people, african americans, latinos who normally don't vote in large numbers in off year elections. >> he's got a party, the democratic party of barack obama is a fabulous party. i saw the statistics the other day. it never occurred to me. he is the only guy since eisenhower who was a war hero, won the second world war to get two 51 percents. he didn't just get it once. he got it twice. he has delivered an electorate. can he do it a third time? >> it's a coalition

>>> welcome to nhk world "newsline," i'm gene otani in tokyo. the fallout from russia's moves to annex the autonomous republic of crimea continues to spread. the eu and the united states have announced additional sanctions against russia, which has responded by announcing its own sanctions. the leaders of the 28 eu member states discussed the annexation issue in brussels. they announced they're adding 12 individuals in russia and ukraine to a list of people subject to travel bans and asset freezes. >> the european council has decided to expand the list of individuals subject to visa ban and asset freeze. some of them are really high ranking. >> this raises the total numb kwer of people subject to eu sanctions to 33. the numbers of the 12 have not been released. the eu leaders say they're canceling a summit with russia scheduled in june, while individual member states say they'll call off bilateral summits with the country. for its part, the united states is also taking aim at russian individuals and corporations. the measures include freezing as

so what nih now does is they isolate genes, they find potential drugs from those genes, they actually do the preclinical studies in labs and in animals, they do some of the actual clinical studies in humans which private companies traditionally do, and then they look for a private partner that's willing to take the drug once some of the risk has been taken out, once they've established that it's a likely candidate. this is the government explicitly creating the future of the pharmaceutical industry. there will be huge profits, there will be huge therapeutic outcomes from this, and it is the free market existing because the government is before our eyes creating it. and then when all is said and done, who buys the products? well, a huge market for pharmaceuticals is the government again. medicare, this is a figure of medicare spending for different components. 11% is outpatient prescription drugs, then there are drugs administered in doctors' offices, drugged administered in hospitals and medicaid. if you put that all together, we're talking about at least $100 billion a year in sales

using gene therapy. dr. pablo tebas help run the clinical trial at the university of pennsylvania. >> our goal is to create an immune system that is resistant to h.i.v., that h.i.v. cannot infect. >> reporter: h.i.v. enters and infects an immune cell by binding to a molecule called ccr5 on the cell surface. 1% of people lack this molecule and are naturally resistant to h.i.v. because the virus is locked out of the cell. dr. tebas and his colleagues extracted immune cells from the trial patients then disabled the gene for this molecule. the cells were reinjected into the patients to try to create resistance to h.i.v. >> we proved the concept that you can modify the cells, infuse them back income tax patient safely, and that they live longer in the presence of h.i.v. >> reporter: as part of the study, six of the patients temporarily stopped taking their medication. in four cases, the levels of h.i.v. decreased. in one of those patients, the virus was reduced to undetectable levels. more than three years later,

. >>> doctors in the united states have used gene therapy to upgrade the new system of 12 patients with hiv. >>> also in the program, aaron is here. another airline jumping on the premium economy. >> yeah, david. it's not economy. it's not business class. it's the hybrid part of the cabin that's cheaper than a regular seat. lounge access, extra legroom and meals on a china plate. we will look to see if all of this is worth it. >>> hello. thanks for joining us here on "gmt". midday in london, 7:00 a.m. in washington, 2:00 in the afternoon in crimea where another extraordinary development has created further turmoil in the crisis in that ream. the parliament of crimea has voted in favor of leaving ukraine and joining russia. and it says there will be a referendum in 10 days's time for people 60% of whom are ethnic russia to make up their mind. they meet in emergency session to consider what actions to take against russia for deploying its forces inside crimea. but hearing from the ukraine's prime minister is governments already responded to the crimean parliament vote saying it's unconsti

. >> gene robinson is with us from washington.bviously, throughout the show we will be covering another major story. i think arguably a far bigger story in terms of its implications depending on what we find out with the plane so not sure yet. on this story, gene, do you have instincts or questions? >> i just have a question for greg feith, which is, basically, does the size or the reported size of the debris that was spotted by the satellite make sense in terms of this type of aircraft? >> gene, there is one piece, that piece 78, 79 feet long, that could be part of this airplane. when you consider that the wing span on the airplane is almost 200 feet that would be a little over, you know, about a hundred foot per wing and the tail section is about 60, 65 feet. that piece that is 79 feet long could be either a wing panel or part of a fuselage panel. so there is a little bit of hope there that, yeah, this piece does match. unlike the chinese debris where they measured it 75x79 there is nothing that large, that square on the 777 so

she got the good genes. >> it's not genetic. you can't always blame everything on your genes.settle. >> she means me. >> who do i have to sleep with around here for a stoli martini with a twist of lemon? >> sandra bullock, "gravity." >> come on. you've got to be kidding me. you've got to be kidding me. [ applause ] >> judi dench, "philomena." >> i want you to know, that i forgive you. >> what? just like that? >> not just like that. that's hard. that's hard for me. but i don't want to hate people. i don't want to be like you. >> meryl streep, "august: osage county." >> you want to show who is stronger? nobody's stronger than me. damn it, when nothing is left, everything is gone, disappears, i'll be here. who is stubborn now, you son of a bitch? [ applause ] >> and the oscar goes to -- cate blanchett. [ applause ] ♪ >> sit down. you're too old to be standing. thank you, mr. day-lewis. from you, it blows it right out of the ballpark. thank you so much, to the academy. as random and as subjective as this award is, it means a great deal. in a year of extraordinary, yet again, extra

you heard him talk about gene haas giving him the opportunity.ut obviously he proved he can handle it and was victorious today. >> what i saw after that mix-up with brad keselowski how he kept his cool, kept his car going straight. all brad was doing was trying to lure kurt in a fight. i just like his maturity and i like who he is today. i like the person that kurt is. he's an awesome race car driver and proved he can get it done against the best in jimmie johnson. >> he wouldn't even take the bait in the post interview that he wanted to punch keselowski in the face. i have to focus. we were trying to get hold of keselowski. clint bowyer slipped away from us. we will have more as kurt busch celebrates. huh, fifteen minutes could save you fifteen percent or more on car insurance. everybody knows that. well, did you know pinocchio was a bad motivational speaker? i look around this room and i see nothing but untapped potential. you have potential. you have...oh boy. geico. fifteen minutes could save you fifteen percent or more on car insurance. cut!

there's that gene, susceptible to addiction. >> bringing up a generation born addicted in vermont. >> twenty five years ago, pan am flight 103 exploded in the skys above lockerbie. only one man was convicted of the attack >> the major difficulty for the prosecution, that there was no evidence... >> now a three year al jazeera investigation, reveals a very different story about who was responsible >> they refuse to look into this... >> so many people at such a high level had a stake in al megrahi's guilt. lockerbie: what really happened? on al jazeera america >> an increasing drum beat. over the increasingly wide use of heroin. "america tonight"'s in-depth series over one of the states that is suffering the worst, addicted in vermont. on this series we look to a new generation, born addicted. "america tonight"'s adam may brings us their story. rg. >> that is quite the cry on him. >> it is. and it's constant. >> jessica says the guilt is overwhelming. every time she watches this video of her baby boy. >> hard to watch, it really is. >> jacks was built physically dependent on the heroin

so with that let me turn to my colleague, gene sperling. i should just say this is a guy that's dedicated to his career toward fostering growth and opportunity for all americans and he will be greatly missed when he returns to his family in los angeles. >> thank you. thank you very much, cecilia. . this is a pro-growth and prothe opportunity budget for the reasons sylvia said. it, one, creates more demand and job growth when we need it. it mablings more room in the domestic discretionary budget for the things that invest in our future and growth and productivity and fairness, and it focuses the reduction in the long-term where it will most important for long-term confidence. it's also pro-growth and pro-opportunity budget because it has very sound evidence-driventi

there's that gene, susceptible to addiction. >> bringing up a generation born addicted in vermont. >> an increasing drum beat. over the increasingly wide use of heroin. "america tonight"'s in-depth series over one of the states that is suffering the worst, addicted in vermont. on this series we look to a new generation, born addicted. "america tonight"'s adam may brings us their story. rg. >> that is quite the cry on him. >> it is. and it's constant. >> jessica says the guilt is overwhelming. every time she watches this video of her baby boy. >> hard to watch, it really is. >> jacks was built physically dependent on the heroin replacement drug, seboxin. >> he cried, he had all the symptoms. there's no subtlety to him. >> crying? >> oh yeah, crying. >> fidgeting. >> fidgeting, starting. the -- startling. the only time he seemed okay was when we were skin to skin, if he was lying right on my chest, that would settle him. >> jessica has lived her entire life in the picturesque town in vermont, the most drug addicted women in the entire country. by age 20 jessica was addicted to heroin an