to set the stage for the discussion today, we will hear from heidi larson. she will share some of the recent analysis about global vaccine trends and explain how what is happening in the u.s. compares to other regions. i will turn the conversation over to steve morrison. co-chair of the panel, to introduce our next speakers and moderate the discussion. before we get started, let me remind those in the audience, there is a button on the events page that will send a question. the mic is yours. heidi: thank you very much. i just have two minutes here to put into context, over the past meetings and discussions, we have noticed and looked at data that has shown the ups and downs of public confidence and willingness since we started the pandemic. last june, these are wave 1, 2, and three. in the u.s.. as well as european countries. we saw the sentiment, the context went down. in september and october. that was after higher optimism or encouraging for a vaccine. that was back in june, the first way. and then september and october. toward the end of the year, confid