our guest is mikhail maschan, doctor of medical sciences, professor, director institute of experimental and molecular medicine. hello, konstantin. we have statistics, they are as follows: annually in russia. these are all tumors, all of the entire pediatric oncology - these are 3,500 patients, 3,700 to be precise, but our area of ​​interest also includes patients with hereditary blood diseases and hereditary diseases of the immune system, what are called hereditary immunodeficiencies, yes, these are diseases in which the immune system stops working as a result of some kind of breakdown - at the genome level, yes, breakdown, most often inherited. in total, the number of patients annually who are part of the area of ​​interest, the center, the area of ​​our competence is about 5-600 people. at what age can the debut of such a disease occur? here the question is a little broken down, because when we talk about childhood cancer or oncological diseases in children, we are talking about several dozen, at least, and maybe several hundred different diseases, and... for each there is its own statistics, but if we talk

and oncology, especially about genetic diseases in children. our guest is mikhail maschan, doctor of medical sciences, professor, director institute of experimental and molecular medicinempetence, this is about 5-600 people, at what age can the debut of such a disease occur? here the question breaks down a little, because when we say childhood cancer or oncological diseases in children, we are talking about several dozen, at least, and maybe several hundred different diseases, and each has its own statistics, but if we talk about the most common tumor in children - acute lymphoblastic leukemia, this a tumor of cells that were going to become cells of the immune system, lymphocytes, but along the way... there was a failure, they turned into a tumor, for the island of lymphoblastic lycosis, what is called, well, the peak, if you want , the incidence occurs at the age of 4 years, but a child can get sick immediately after birth, at 18 years old, and you said that it is hereditary, that is, these are the children of parents who are already sick, why, why does this even occur, why at 4 years old, why not immediately, is the first hereditary cause? this tumor? and the answer