institute. it was a very long period of time. we conducted research first on experimental animals. this is, of course, the white laboratory rat of our vivarium. institute of physiologys mellitus. in particular research. this issue was covered somewhere. well, about four years in the final stages. e. we also looked at some laboratory parameters and cells blood already of patients who have been verified, that is, diagnosed with diabetes mellitus in cooperation with clinicians, the main conclusions, the most important very first target that takes the blow in diabetes mellitus. this is me brain weight. that is, it was the vessels of the microvasculature of the brain and the brain tissue that were damaged in the first place. e, ultrastructures of endothelial cells, that is, those cells that line inside e, vessels of blood growth frontal lobes. and changes were expressed with side of the platelets, that is, they were prone to increased aggregation. that is, they accumulated together formed such conglomerates and pronounced changes in red blood cells, that is, erythrocytes. and when we examined the erythrocytes of experimental animals. it was a very pronounced picture, tha