institute. it was a very long period of time. we conducted research first on experimental animals. this is, of course, the white laboratory rat of our vivarium. institute of physiology diabetes mellitus particular research. this issue was covered somewhere. well, about four years on the final. we looked at the smell of e and some laboratory indicators and blood cells of already patients in whom it was verified, that is, a diagnosis of diabetes mellitus was established in cooperation with clinicians, the main conclusions. the most important the very first target that takes a hit in diabetes. this is me brain weight. that is, it was the vessels of the microvasculature of the brain and the brain tissue that were damaged in the first place. e, ultrastructures of the endothelial cells, that is, those cells that line the frontal lobes inside the e vessels of the bloodstream. and changes in platelets were expressed, that is, they were prone to increased aggregation. that is, they accumulated together formed such conglomerates and pronounced changes in side of red blood cells, that is, erythrocytes. and when we examined the erythrocytes of experimental animals. it was a very pronounced pictu