. >> rose: jay bilas, walter isaacson, charles duhigg when we continue. captioning sponsored by rose communications from our studios in new york city, this is charlie rose. >> rose: the n.c.a.a. basketball tournament is in full swing. a field of 68 teams is down to the sweet 16. the games will be played tomorrow and friday in arenas across the country. all four of the top seeds remain in contention. they are kentucky, north carolina, syracuse, and michigan state. kentucky has dominated all year, the wildcats look to avenge an early season loss to indiana on friday night in atlanta. north carolina enters week two with a big concern at point guard. its top play maker kendall marshall broke his wrist in the second round last weekend. his status is uncertain. joining me from charlotte, jay bilas, he is a college basketball analyst for espn and a world-class attorney. i am pleased to have him back on this program for march madness. welcome. >> thank you, charlie. great to be with you, as always. >> rose: what do you think of the tournament so far as predicted

dale isaacson and marilyn burson is say this is one of the first devices that can work on all body partseverything from eyelids to necks to love handles and thighs. they say it works by first cooling the surface of the skin and using radio frequency, it slowly heats the deeper fat tissue. this allows the fat to literally melt away. >> you just pee it out. you have to drink a lot of water with this. we advise our patients to go ahead and drink a couple liters of water. >> reporter: most patients require at least four treatments for the best results. but 63-year-old sandra, who is trying to tighten up her face what happened she calls her turkey neck, says she noticed a difference after just one treatment, and so did her husband. >> when a man notices, it's really pretty amazing. >> reporter: this is sandra before and this is after three treatments. pam leighton is trying to slim down her tummy. she was considering a tummy tuck, but was attracted to excelis because it's cheaper. >> other surgeries are $6,000, and this is, you know, half of that, for the most part. >> reporter: both women sa

. >> senator isaacson? >> thank you, i appreciate you being here and your great contribution not just the united states but the whole community. i'll start off with a parochial question and i doubt if you know the answer but if you do -- peanut crisp program a collaborative research support program flew ua said, a five-year contract that ends at the end of this year and is being reviewed for extension. a number of universities of which the university of georgia is one participating in the program and they recently found -- aflotoxin and tied it to immune systems and they're making a breakthrough and turning it around. my interest is to find out what the status of that review is and what the agency thinks of what's been produced so far by the peanut crisp program, if you wouldn't mind. >> that has been an external evaluation that's under way. we've tried to restructure our entire research strategy and agriculture and food security and this is part of that review. i will explore the details and come back to y

and we will be led into lunch by robert isaacson who will be talking about the latest auto y autobiography of steve jobs. later we have the honor of hosting senator kerry, and i know he will be super keen to answer all your questions. so we should take advantage of the opportunity to have one of the department's biggest champions here to actually ask him his thoughts and his guidance. then this afternoon we've arranged for what i hope you will find to be a very hopeful -- i mean, a very useful series of seminar style breakout sessions as well as other information on discreet areas of foreign policy. we'll actually close way town hall session that will be here with the secretary as well as the washington-based leaders to be able to answer any questions and have a free-flowing discussion, which we all are looking forward to. i just want to take a quick moment to say that during the break there is actually an exhibition hall of different parties who have set up different points of contact who can answer questions about programming and answer other information that you all might find useful ou

we will be led into lunch by author and policy thought leader walter isaacson talking about leadership and drawing on the recent biography of steve jobs. then at lunch weve of hosting senator john kerry will who will be sharing his perspective on congress. he'll be super keen to answer your questions. we should take advantage of the opportunity to one of the department's biggest advocates to ask him his guidance. this is afternoon we've arranged a very useful series of seminar styl sessions as well as other information on discreet areas ofeie with a town hall session here with the secretary as well as with the washington-based leaders here to be able to be answer any questions and actually have a flee-flowing discussion. then i just want to take a quick moment to flag during the break there is a number of department who have set up different points of contact where they can answer questions about programming and offer other information that you all might find useful out in the field. if you could take a moment to go through there, that would be useful to you. before we get started, i w

billionaire genius which business week has compared both to and leonard caper and trashy analog to walter isaacson's biography of steve jobs. king larry begins on may 21st, 1995, which if you were in the state was heavily from the adjacent and murder trial. but with a beautiful sunday morning hand a small plane who took off from the airport with two important people on board. one was the speaker of the house of the commonwealth of the northern mariana islands and the other was mary home better known as dhl. .. >> so a number of his friends had declined to make the trip with him that morning, and no one was terribly shocked that this plane had also gone down. however, it was a real shock that larry hillblom was suddenly gone. he'd arrived there 15 years before, and he'd become a larger-than-life character in the mariana islands. he bought the bank, he bought the airline, he bought the television and radio stations, he built dozens of businesses including the pawnshop and had been a bartender, so he was very well known. and there was a sort of myth those that was just incompatible with him being dead.

was trying to survive to see his son at his high school graduation to his was a quote to walter isaacson. i think the biggest innovation of the 21st century will be the intersection of biology and technology. that's what we are talking about tonight. so now let's talk more about the real biology, not just ideology of all these different metrics. let's talk about sequencing. that's still digital. for characters. but all of us basically, each of us i should say are just billions of zero ones actg, from a medical standpoint. yes, we have a soul and personality, and we're human and all that stuff but from a medical personality you only need six characters. the way we sequenced people in the past was using these next-generation devices that cost seven, $800,000, next-generation of sequencing the not only would incredibly expensive but we had to buy these proprietary agents and these were formidable. we are in this era. this year in january we thought this is really big. life technologies announced this, not yet feasible will be later this year can sequence a whole human genome 40 times, seque

cooney. >> i heard people saying, have you seen johnnie isaacson? >> senator udall? >> i think i will follow the lead also of our republican colleagues and tried to move as quickly as possible, if we can. let me just thank the ambassador for your testimony and leadership on this issue. you have mentioned that president obama and secretary clinton have been actively involved and we also appreciate their assistance. with that, i will yield back. >> we have bipartisan agreement it is time to move on. thank you very much for your service. >> i think we have to schedule this around a really controversial vote. >> i would not say, all of us, just for the audience -- we have the ability to ask questions of these officials. that is why moving on makes sense. >> before we excuse you, i want to ask if there is anything that you feel you wanted to say and did not have a chance to, or, ambassador? >> highs the committee very much. i do not think the crowds were out there -- were out there to see us, either. >> we are going to work with you as closely as we have. we will try to s

conscience and the leadership of the museum for organizing this evening and on behalf of walter isaacson and the aspen institute how glad we're partnering on this important event but partnering on this particular subject comes to us naturally. i'm proud to say harold coe was a regular moderator at the seminar for judges run for many years at aspen's white river facility by our merida director with professor lewis hankin of columbus law school two key developers and components of the modern field of human rights and humanitarian law. some of the justice and society programs' recent efforts are focused of development of the rule of law around the world including in the arabian gulf and the spring countries and i want to observe that it is through the rule of law, through vigorous legal and judicial institutions that we are able to prevent the perpetration of the most grievous offenses by the unbrideled against discrete and insular minorities. tonight we'll hear of the courts and more recently the international criminal tribunal for the former yugoslavia and the international tribunal for r

later today, senator isaacson and i will be joined by senators durbin and wicker for considering legislation that supports the efforts all of you have talked about that calls for the government of sudan to allow humanitarian access to conflict areas and calls on sudan and the north to reach mutually beneficial agreement to end their conflict. that is one of many things we in the congress can and should be doing to continue what has long been a bipartisan tradition of engagement leadership on these issues. george, you) referencing the folks to stay up all night. the energetic young people who process images from the satellite project. in a few weeks we have seen a flood of interest in joseph kony. you have both been very effective in getting americans and folks around the world to pay attention to a grave humanitarian crisis in a fairly remote corner of the world. what advice do have for all of us who want to sustain and engage americans and folks were broadly in continuing to be concerned about a humanitarian crisis such as exists in darfur and the nuba mountains and with joseph kony. how do

a famous book written by walter isaacson writ steve jobs recently and here is quote from the book theking. we told the publishers we go the agency model. where we set the price, you set the price, publishers and we apple, get our 30%. the customers pay a lot more. that's what you want anyway, we're left, jenna, paying more for the books than we ordinarily wouldn't have. we don't know the other side the publishers and others refused to comment. jenna: i know you're a big apple guy. you have a iphone and ipad, all that sort of stuff. >> yes. jenna: i have a kindle though. what about amazon, barnes & nobles? there are a lot of different devices in ebooks. are they involved at all in? >> no but they kind of started this when you think about it. amazon, which is interesting the agency model dell previously the wholesale model the it was sold half price. $24 book sold for 12 bucks. amazon comes in with the kindle we'll give you to you for 9.99. publishing companies hated that. maybe that is why they were quick to make a deal with steve jobs. the publishing companies didn't basically want to

. >> senator, isaacson. >> i too will be very brief because i'm anxious to hear from each of you.ry thank you for taking the time to come to my office two weeks ago. secondly have two pieces of business. one is on the jobs from. you probably have heard about this but i want to make you aware. the founder of air train which is now southwest has created a foundation called gratitude america which is a web-based platform to match job needs with veterans. it has a component that links them with training for jobs where for veteran is looking for a job he can search it on the internet and if he finds a job he likes but he's not qualified it matches and with the closest training facility where he can get the training. i think it's a great idea. it's something that's very important and i appreciate lewis doing it and i thought you'd like to know. sec and i want to complement director goldman who spend a day in dublin georgia last week. he cedes -- surged 51 counties and he is trying to partner with a commander of roberts air force base to merge the va clinics and terry georgia and macon g

senator isaacson. >> i, too, will be very brief because i'm anxious to hear from each of you. secretary, thank you for taking the time to come to my office two weeks ago. secondly, i have two pieces of good news. one's on the jobs front, and you probably have heard of this, but if you haven't, i want today make you aware. louis jo done who is the found -- jordan has created a foundation called gratitude america which is a web-based platform to match job needs with veterans, and it has a component that links them with training for the job, so it makes the full circle where if a veteran's looking for a job, he can search it on the internet. it matches him with the closest training facility where he can get the training. i think it's a great idea, and it's something that's very important. i appreciate louis doing it, and i thought you'd want to know. i want to complement director goldman in dublin, va, and he's trying to partner with the commander of robbins air force base to merge the va clinics in perry, georgia, and macon, georgia, with the base dod health care on the base to

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best sellers, number six, water isaacson's book, he was on yesterday, "steve jobs."ch 26th. i had no idea it was still -- >> when did the book come out? >> last may. >> so it's still selling. >> still selling. now the paperback is coming out. but in the last year -- did you see? >> yeah, this is big news dpup see this yet, blake? >> yes, i did. >> there's an ad in the wall street journal talking about the release of the paperback. blake, what has the last year been like with everything that's come with this? >> well, we went to a lot of places to talk about the book. >> the most exciting place and we're going to show a picture. remember when we were up there? remember the winklevoss triplets? we went and spoke at harvard business school. remember the name of the society we spoke with? >> the -- >> adam smith. >> adam smith society, the guy with the invisible hand. >> then she got to see harvard college and hogwarts, which is where the undergraduate -- did you ever see that? you were an ivy league -- >> i never saw it. >> that was amazing. i mean, look at that. >> the

sullivan, is going to be leading a panel discussion, and then we will be led into lunch by wall tar isaacson, who will be talking about leadership, and drawing on the biography of steve jobs. and then at lurch we have the honor of hosting senator john kerry he will be super keen to answer your questions. so we should take advantage of the opportunity to have one of the department's biggest champions their actually ask him his thoughts and his guide. this afternoon we arranged what i hope you will find to be a very useful series of seminar style breakout sessions as well as other information on discrete areas of foreign policy and will we close with the leaders to answer any questions and have a free-flowing discussion which we're all looking forward to i just want to take a quick moment to flag during the bleak actually is a number of departments set up different points of contact where they can actually answer questions about programming and offer other information you might find useful in the field and if you can take a moment to go through there, that would be useful. and i just want to t

the other thing i would say is senator isaacson mentioned i do appreciate the fact that you are very willing to work with congress, and very approachable, and you and your staff, and so that's something that is appreciated. we appreciate all that you have done in the past and are looking forward to you doing a bunch in the future and i yield back madame chair. >> with that i want to welcome again, secretary shinseki. thank you for coming today to get your perspective on the department's fiscal year 2013 budget and fiscal 2014 advanced appropriation request. secretaries shinseki is accompanied by steve muro, allison hickey, undersecretary for benefits, dr. robert petzel as a country for health and and we also have todd grams for the office of management and chief financial officer and roger baker assistant secretary for information technology. thank you all for joining us today. s and secretary shinseki, your remarks will appear in the records and we welcome your opening statement. >> thank you madam chairman and distinguished members of the senate committee on veterans affairs, thank

i heard people out there saying have you seen johnny isaacson? >> senator you'dle. >> i think i'm going to follow the lead also of our republican cletion here and try to move as quickly as possible as we can. let me just thank the ambassador and ms. lindberg for your testimony and your leadership on this issue. and you have mentioned that president obama and secretary clinton have been actively involved. we also appreciate their assistance there. with that i yield back. >> thank you senator. senator brasso. >> mr. president, we have bipartisan agreement it's time to move on. thank you for your service. >> wow. i think we need to try to schedule this thing around a really controversial vote here. >> i would say all of us just for the audience we have the ability to ask questions of these officials and get back. so i know we'll all take the opportunity to do that. and that's why moving on makes sense. >> before we excuse you i just wanted to ask is there anything administrator lindberg that you feel you wanted to say that you haven't had a chance t

we will go to lunch with walter isaacson, who will talk about leadership and drawing on the recent biography "steve jobs." at that lunch, we have the honor of hosting senator john kerry, who will be the keynote, sharing his perspective on congress. i know he will be super keen to answer your questions. we should take advantage to that opportunity, having one of the department's biggest champions here. this afternoon, we have arranged what i hope you will find to be a very useful series of seminars-style break out sessions, as well as other information on discrete areas of foreign policy. we will close to the tunnel session here with the secretary, as well as with the washington leaders here. i want to take a quick moment to flag that during the break, there actually is in the exhibition hall a number of departments who have set of different points of contact where they can actually answer questions about programming and offer other information that you might find useful in the field. if you could take a moment to go through there, i think that would be useful to you. before we get started, w