jacobson v. massachusetts, 1905.there was a pastor in cambridge who refuse to get vaccinated for smallpox. said it was a religious objection. the supreme court said, too bad. you live here, you are getting vaccinated. tough luck. the bottom line is there is a point at which every person responsibility issue becomes a public health one. and the question is -- where is the line and what are the legal doctrines that govern the crossing over of that line? i would submit to you that we have surpassed that for this problem. yet we have not enacted any societal interventions that are meaningful to try to fix it. that is what needs to change. >> thank you, dr. lustig. i was wondering if you could speak little bit to other disease in addition to obesity, such as autoimmune disease. >> autoimmune disease is a grab bag. this is being televised, taped. and i am about the science. the science on auto immune disease is very much an open question. so i am a little loathe to tell you how all of this might tie into autoimmune disease