. >> jay smith was at the height of his career as ceo of a music technology company when he was diagnosed with als. it's a form of motor neuron disease like that suffered by british physicist stephen hawking. there is no cure, and smith's disease is progressing. >> in this year we started with minor fatigue and slurred words. a year later we're in a wheelchair. the hands aren't working the smith is going. >> the food and drug administration is the body of government that approve drugs used in the u.s. they want to speed up drugs that could help save jay's life and others. they want the process reformed so those who have access to developmental drugs before they're approved. >> we're telling the food and drug administration today that the status quo is not good enough. they need to do everything in their power to speed the surge for a cure. >> the fda approval process can take more than a decade. the average als patient lives an average of three years from diagnosis. fighting the government for a right to try experimental medications. the right to try movement is pushing legislation to alt

it was a privilege forme to be able to write this book with jay smith. and it was a privilege to take this journey with all of and you for the support that i have got end dan cane. he could not have done it without you. there are many so people in the room that made this happen i think that in the long run it will really make a difference, we will be on the right side of history. yeah. yeah. so we would be happy to answer any questions we love "q&a." we love it. we love to be strumd. thank you. [applause] you mentioned. this. obviously. this is the way that it has to start. no question of that the poor young fell as are coming into the big university which such standards that are demanded of them. they just as a nba and nfl. and that is the only route that they have to be seen by the scouts it is my opinion that there should another route of the two bodies. so that they can get there to earn the money that they are entitled to. i believe that. sovp two separate systems is what the gentleman is suggesting so profit sports. a semi- pro type of league if yo

. >> ten months ago jay smith was at the height of his career as a ceo of a music technology company when he was diagnosed with als. it's a form of motor neuron disease like that suffered by physicist stephen hawking. there is no cure and smith's decease disease is progressing. >> a year later we're in a wheelchair. the hands are not working. the speech is going. >> the smiths have lobbied the food and drug administration the body that regulates drugs in the usa. they want faster approval of a development drug they hope could save jay's life and others. they also want the fda approval process reformed so patients with fatal illnesses can access developmental drugs before they are approved. >> we are telling the status quo is not good enough. they need to do everything in their power to speed the search for a future. >> the fda approval process a can take more than a decade. the average als patient lives three years from diagnosis. so a movement has been formed to fight government for the right to try. >> the right to try movement is pushing for legislation that would dramatically alt

. >> ten months ago jay smith was at the height of his career as an executive with a major company, and. >> a year later we're in the wheelchair, the hands aren't working, the speech is going. >> smith has joined dozens of other patients to lobby the food and drug administration. they want faster approval of gm 604 that they hope will save smith's life and others. so patients with fatal illnesses can access developmental drugs before they are approved. >> we are telling the fda today that the status quo is not good enough. they need to do everything in their power to speed the search for a cure. >> reporter: the fda approval process can take more than a decade. the average als patient lives just three years from diagnosis. so a movement's been formed in the u.s. fighting government for the right to try experimental medications. the right to try movement is pushing for legislation that would dramatically alter the way medicines are regulated in the united states allowing for possibly lifesaving developmental drugs to be fast-tracked for the patients who need it. ten states have already g

. >> reporter: ten months ago jay smith was at the height of his career as ceo of a music technologycompany when he was diagnosed with als. it's a form of motor neuron disease like that suffered by physicist stephen hawking. there is no cure. >> it started with slurred words. now we're in a wheelchair. the hands aren't working. the speech is going. >> smith has joined dozens of other als patients to lobbyer food and drug administration the body that regulates pharmaceuticals in the u.s. they want access to an experimental drug that could save jay's life, among others. they also want reform so patients can access experimental drugs. >> we're telling them that the status quo is not good enough. they need to do everything in their power to speed the search for a cure. >> the fda approval process could take more than a decade. the average als patient lives three years after diagnosis. fighting government for the try right to try experimental medications. >> the right to try movement would like to alter the way experimental drugs are used in the united states and allowing experimental dru

. >> reporter: ten months ago jay smith was at the height of his career as ceo of a music technologyompany when he was diagnosed with als. it's a form of neuromotor disease suffered by similar to the decease effecting stephen hawking. >> the hands aren't working. the speech is going. >> the food and drug administration is the body that regulates pharmaceuticals in the u.s. they want them to pass the drug that they hope would save jay's life. they also want access to experimental drugs before they are approved. >> we're told that the status quo is not good enough. they need to do everything in their power to speed the search for a cure. >> the approval process could take more than a decade. the average als patient lives three years after a diagnosis. >> the right to try movement is pushing for legislation that would dramatically alter the way medicines are regulated in the united states, allowing for potentially life-saving developmental drugs to be fast tracked for the patients who need it. >> ten states have already granted terminally ill patients access to developmental medicines w

from washington: >> 10 months ago jay smith was at the height of his career as the c.e.o. of a technology company when he was diagnosed with a.l.s. there's no cure and smith's disease is progressing. >> in this career, we started with minor fatigue. a year later we're in a wheelchair. the hands aren't working the speech is going. >> the smiths have joined dozens of other a.l.a. patients to lobby the u.s. food and drug administration, the body that regulates pharmaceuticals. they want faster approval of a developmental drug called gm604 they hope can save jay's live and others. they want the f.d.a. approval process reformed so patients with fatal illnesses can access developmental drugs before their approved. >> we are telling the f.d.a. today that the status quo is not good enough. they need to do everything in their power to speed the search for a cure. >> the f.d.a. approval process can take more than a decade. the average a.l.s. patient lives three years from diagnosis so movements have been formed in the u.s. fighting government for the right to try experimental medica

. >> jay lin brian smith. >> i felt like screaming.of myself snoor. >> stevenson. >>> thought i wasn't going to be one of them. >> reporter: middle school students from 49ers academy take the stage to celebrate their success in learn storm, a bay area math competition from waun contacted me. >> we had 1500 schools participate. and the 49ers academy in east palo alto is at the very too much it in the hustle leader board. >> it ranks perseverance and grit, schools with students who have the tenacity to stick with it even when the going gets tough mathematically speaking. >> you have to get five right in a row. on that fifth question in my room you will hear oh, but they don't stop. they don't give up. >> i think republican's mid-ms. understood that it's only to get kids to do better in math. >> john is with a nonprofit news and research organization. >> his goal all along has been to produce confident learners who want to go at their own pace and succeed at their own pace. >> times six times ten -- >> reporter: back at the middle school

. >> jay lynn brian smith. >> i felt like screaming, i was so proud of myself. >> mariah stevenson. >> i thought i wasn't going to be one of them. >> reporter: middle students from frieners are49ers academy take the stage. >> we have had 1,500 schools participate. and the 49ers academy here in east palo alto is at the very top of that what we call our hustle leaderboard. >> reporter: it ranks perseverance and grit students who stick with it even when the going gets tough, mathematically speaking. >> you have to get five right in a row. so on that fifth question, you hear oh! and you know that's when a student has failed that last question. but they don't stop. they don't give up. >> i think it's been misunderstood that it attempts simply to get kids to do better in math. >> reporter: he is with edsource, a nonprofit education news and research organization. >> but his goal all along has been to produce confident learners who want to go at their own pace and succeed at their own pace. >> reporter: back at the middle school students keep on hustling in con academy, learning not just mat

jay leno. from "barely famous," sara and erin foster. comedy from seaton smith.eaturing the 8g band. ♪ [ cheers and applause ] and now, here he is, seth meyers! ♪ [ cheers and applause ] >> seth: good evening, everybody. i'm seth meyers. this is "late night." how's everybody doing tonight? [ cheers and applause ] exciting to hear. any college basketball fans here? [ cheers ] all right we got some. well, then i don't need to tell you that march madness is officially under way today, and there have already been some major upsets. for instance, i told my wife i was going to watch basketball all weekend, and she was majorly upset. [ laughter ] majorly upset. [ applause ] but i'm probably not going to watch basketball all weekend because in our relationship, she's a one seed, and i'm a sixteen. [ laughter ] there's been a lot of news about the secret service lately. the head of the secret service spoke to congress today and lashed out. he lashed out at reports that agents had crashed a vehicle near the white house. but in his defense, he was pretty drunk. [ laughter ]

joining me janet mock msnbc contributor and host of so popular on shift by msnbc, mychal denzel smith and jaye headline alone, ethnic casting, that term -- >> i love it. >> you've got to cringe at it. i've got to cringe. but the real issue here is that you know, people might actually be listening to this. hollywood executives might be reading that "deadline" piece and say you know what they're right. we've got to stop this ethnic casting before it gets out of hand and these poor white people are out of work. >> here's one thing that maybe is happening, maybe is happening that might be interesting and that is this idea of a difference between -- and whether or not there's a meaningful distinction between roles that anyone can sort of -- versus writing for telling a story. so think with "blackish" and "fresh off the boat," they are telling stories of communities versus i'm thinking bringing a certain flavor through your own identity. >> everybody talks about color blind casting which i don't quite believe in and i think right now there seems to be an effort to really cast people and create role

. >> reporter: so the smiths have joined dozens of other als patients to lobby the food and drug administration. an experimental drug they hope will save jay's life and others. they want the fda approve process reformed so patients with fatal illnesses can access developmental drugs before they are approved. >> we are telling the fda today that the status quo is not good enough. they need to do everything in their power to speed the search for a cure. >> the fda approval process can take more than a decade. the average als patient lives only a tu years. the way drugs are regulated in the united states allowing for potentially lifesaving developmental drugs to be fast tracked for the patients who need it. ten states have already granted terminally ill patients, access to drugs without approval. similar laws are in place in other countries. >> in europe drugs tend to get approved earlier. in this country they could be approved earlier for serious lifesaving cases, it is doable. >> the smiths say they simply want the same opportunity. >> that is really first thing if i have to wait, i won't be around. >> reporter: they say they're already in th

smiths have joan dozens of others to lobby the u.s. fda. they want faster development of a experimental drug that will help jay's life and others.y want the situation performed, so patients can access developmental drugs before they are approved. >> we are telling the fda that the status quo is not good enough. they need to do everything in their power to speed the search for a crew. >> the fda approval process could take more than a decade. the average als patient lives less than three years. the right to try experimental medications. the right to try movement is pushing for legislation that will alter the way experimental drugs are administered in the united states, allowing fast tracking for the patients who need it. 10 states have already granted certain patients access. other countries have similar laws. >> in european countries, drugs seem to get approved earlier. it's doable. >> the u.s. government last year allowed u.s. ebola patients to receive lifesaving experimental medicines, the smiths say they simply want the same opportunity. >> that's really the important point. if i have to wait, i won't be around. >> reporter:

so, jay ignores i think, or he leaves out of this book, the basic adam smith or fredic hayak critique. adam smith complained about what the called the nano system, the people who get in government and think they can sort of centrally plan the economy as if the economy was just a society was like a chess board that the government can manipulate. that this problem with big government. i don't think -- i think jay's critique is that if the hamiltonian or henry clay kind of big government system could perhaps have worked if washington -- if we had changed the institutions in washington over the decades itch don't think that's right. i think that big government fails because it tries to centrally plan. a second opinion and maybe this is more -- i thought it was very interesting, maybe a bit of an agreementy -- is that the madisonian view of checks and balances and that factions in the extended republic would substance each to the public good. maddison pay lint through -- jay can correct me m -- didn't see the rise of log rolling. it's a crucial problem in government and jay goes into this

jay of course. >> and you don't have to say that. >>> we have this member or rised. >> and this is a coaching legend. dean smith.. you can see, everyone is jumped about i their work. he is one of the winningest coaches. the only guy to hold michael jordan to 16 points he made him pass the ball. came out today. he died in february at 83. directed his final wishes to have a letter and a $200 check every player that lettered during his tenure. that's 180. they had a message enjoy a dinner out compliments of deep dean smith with the check attached. now that's, that is very cool. >>> the warriors, leaving for memphis. they go against the grizzlies. no way they are going to catch them. but they may meet up in the western conference finals. so, they want to play well tomorrow night but 11 to play. 8 and a half up. and the win is they will tie the records for most minutes in a season with 59 and didn't take long for the team to put up the banner. you know by now. 39 years since one of those went up. and talking about raising the banner. >> i'm not sure whose idea it was. i love it. it is important to acknowledge that. a

. >> other winners included grammy favorite sam smith taking home best new artist. and jesse jayered in chains singing his song of the same name. superstar rihanna took the stage by helicopter to perform her new single. the show also had what many thought was a sour note. >> we have bruce jenner here. >> host jamie fox joking about tv star bruce jenner's reported sex change. >> he is doing a his and her duet all by himself. >> the backlash was immediate. >> but justin timberlake stole the spotlight accepting the award and offering this advice. >> i'm here to tell you, your critics do not count. their words will fade. you won't. >> jacob rascon, nbc news los angeles. >> nice speech from jt. it was a big night for music. today could mark big changes in the streaming before midnight. jay z tweeted out this. the tides they are a changing. it has been trending in reference to jay z's new launch of another big business this time in the streaming music service called tidal. it is said to provide high fidelity quality sound. it will be expertly curated. several artists are changing their