people now began to explore a number of neurological diseases and jerry fischbach is going to speak about that and saw that all of them could be localized to one or more areas of the brain, neural circuitry of the brain. when psychiatrists began to explore the brain or psychiatric disorders, schizophrenia, depression, addiction, they didn't find obvious lesions in the brain. and so many thought that these are not brain-based disorders, these are mental disorders. and a few far-sighted psychiatrists realized early that it's very likely that they are brain disorders but undetectable with the techniques available. the situation changed remarkably in the last 40 years. a new synthesis occurred within psychiatry giveen in good part by basic science. first of all, that was sort of philosophical synthesis when cognitive psychology, the science of the mind, merged with neuroscience, the science of the brain, to formulate a new science of mind. and as we discussed in the earlier series, fundamental assumption of the new science of mind is that every mental process-- from the most trivial one, hitt