in 1954, a vaccine to prevent paralytic polio developed by jonas salk was tested in the largest fieldrial and medical -- field trials in medical history. finally in 1955, salk vaccine is safe and effective. the next challenge is production in quantity. a huge task, a complex process all detailed in this book. it is officially called a protocol. here, the manufacturer records every step in the production of one lot of vaccine. the first requirement is trained scientists and technicians. their every action is important starting with the scrub up. the equipment they use get scrubbed up. a scalding steam bath for 15 minutes. when it comes out, it is completely sterilized, ready for the job ahead. vital to the production of the vaccine are monkeys from the far east. given the best of care. meanwhile another basic , ingredient of the polio vaccine is being prepared. a rich, nourishing liquid called medium 199. some 68 different elements going to medium 199. -- go into medium 199. each is carefully checked, weight, and combined according to the formula. when all is thoroughly blended the med