he saving _ invested —— jonathan van—tam. he saving hold — invested —— jonathan van—tam.it longer because we don't want to do anything _ longer because we don't want to do anything to— longer because we don't want to do anything to throw us off course. so, hopefully— anything to throw us off course. so, hopefully not too long to go. but the oint hopefully not too long to go. elf the point you're making, sam, at the other end of this is you're right, it's been tough for us but it's hardly been toughest for on the front of the i. freedom after a year indoors. so good, such aood after a year indoors. so good, such good neva- — after a year indoors. so good, such good news. people _ after a year indoors. so good, such good news. people in _ after a year indoors. so good, such good news. people in care - after a year indoors. so good, such good news. people in care homes i after a year indoors. so good, such i good news. people in care homes that from tuesday, i will be able to venture — from tuesday, i will be able to venture out of the ground, they'll be able _ venture out o

i'm jonathan van tam, deu from the jcvi. i'm jonathan van tam, deputy chief— from the jcvi. edicines. today's briefing is about the uk vaccine programme, and in particular, about the astrazeneca vaccine and we will explain as we go through about a change of course, a course correction, if you like, to the uk programme. now, if you had said to me back in march 2020, and predicted how far we would have come so far with our vaccine programme, then i am not sure i would have believed that we would have got as far as we have. the uk vaccine programme has been the most enormous success indeed. and if you said to me that by march 2021, we would not have needed a course correction, that also would have amazed me stop so we must keep this in the context the enormous success —— of the enormous success we have achieved so far. i'm going to stop there so far and allow professor raine to open the briefing by explaining her perspective from the mhra and where we are arriving at today. thank perspective from the mhra and where we are arriving at today.— we are arriving at today. thank you.

jab, and i can understand by today government ministers have been out, as you said the deputy, jonathan van tame. numbers of the joint vaccination and imitation committee, try to allay people's fears. but it is difficult because of course people will see these headlines and think, gosh! and i know friends myself, i have a friend much younger than me who has had the ashes into vaccination because of underlying health conditions that she herself posted on facebook saying, "i am a bit concerned about this. i have talked to my doctor, done a bit of research, and i'm glad i've got it the if i can offer the second one i will take it," and i think it is important for people to ask questions. it is important for all these medicalfigures in leading epidemiologists and scientists to be out there and talking to people, because the danger is you do not want people to know lose trust in what has been a really, really successful vaccine roll—out programme, and there has been some slightly lower hesitancy, for example, with some members of the ethnic minority committees, so it is really important to try and k

we will be hearing from the deputy chief medical officer for england, jonathan van tam among others.fferent. what you know about this? what do a peaky blinders themed bar and a custom—built yoga studio have in common? they're both contenders to be named "shed of the year". graham satchell has been to meet the people whose humble shed is their pride and joy. we don't like to call it a shed. it's wooden—built, but it is a yoga and pilates studio, which is where i teach and work. i'd have said probably for 15 years, over and over, "i would love to have my own studio, i would love to have my own studio," and, ta—da! my husband goes, "hmm, ok." so began a mammoth lockdown project. geraint has spent most of the last year building a yoga studio for his wife, mel, in the back garden. it's been incredibly enjoyable, hugely satisfying to be able to stand in the kitchen window and look down and see something that i've created myself is just fantastic. the finished studio has underfloor heating, wi—fi, sound and vision. it's allowed mel to do her classes online. mel started doing yoga to help he

said, don't _ not, jonathan van—tam famously said, don't make _ not, jonathan van—tam famously said,ra. uk has ordered 70 million doses. it has. a while ago by the mhra. uk has. ordered 70 million doses. it has to be cotd _ ordered 70 million doses. it has to be cold stored, _ ordered 70 million doses. it has to be cold stored, not _ ordered 70 million doses. it has to be cold stored, not as— ordered 70 million doses. it has to be cold stored, not as cold - ordered 70 million doses. it has to be cold stored, not as cold as - ordered 70 million doses. it has to be cold stored, not as cold as that| be cold stored, not as cold as that of isaac— be cold stored, not as cold as that of isaac vaccine. _ be cold stored, not as cold as that of isaac vaccine. the _ be cold stored, not as cold as that of isaac vaccine. the trials - be cold stored, not as cold as that of isaac vaccine. the trials are - of isaac vaccine. the trials are very— of isaac vaccine. the trials are very encouraging, _ of isaac vaccine. the trials are very encouraging, against - very encouraging, against mild—to—moderate

you can watch the briefing which is being led by deputy chief medical officer for england jonathan van tamfrom him at 3pm this afternoon. you will be able to watch that briefing live on the bbc news channel. brazil has recorded more than 4,000 coronavirus deaths in 2a hours — a grim record for the country. the public health system has been overwhelmed by a surge in the number of cases since the beginning of the year — as paul paul adams reports. sobbing. 0vercrowded hospitals, a health system on the brink of collapse, and a population living in fear. covid's spotlight has ranged across the globe and now has brazil locked in its harsh glare. for the first time the country has recorded more than 4,000 covid—related deaths in just 24 hours. brazil's death toll now stands at around 337,000 — second only to the united states. still behind both the us and britain in terms of death per capita, but a contagious new variant is fuelling the latest surge — the death toll in march twice as high as the previous month. i think brazil now is not only the epicentre of the pandemic worldwide, it's a threat

jonathan van _ for? it is an ongoing process and jonathan van tam _ for? yes, we can see from real—world data that public health england has published that the vaccines offer really high levels of protection for you if you have been vaccinated with one dose, even more with the two doses. will it also reduced transmission? yes, we've seen the data from public health england that it reduces household transmission by 50%. the durability, how long does the protection last, both in terms of antibodies and t cells is more challenging. that was the question thatjonathan van tam was getting at, the way that we do this at the moment is to see how the antibodies are able to deal with the virus variants, the south african variant, for example. it's harder to see how the t cell protection also kicks in and protects you from severe infection and hospitalisation, but the scientists will continue to do that work and they will then make the decision as to when to offer the booster jab to which the decision as to when to offer the boosterjab to which groups, and see the mo

who was joined by dr nikki kanani from nhs england and professorjonathan england and professor jonathan van—tamder night than the previous night with lengthy clear spells for many away from the south—east. that early rain and cloud, it will clear away from east anglia and the far south—east fairly quickly and then it's a bright day for all areas, a frosty start for many and then showers developed in the afternoon and become more widespread and heavy with some hail and thunder mixed in as well. factor in that very brisk north north—easterly breeze, especially across the eastern side of the country, and it will feel chilly, these temperatures below par for the time of year and struggling to get into double figures in scotland and the far north—east of england. for friday, a frosty start, some sunshine around and then showers will get going again during the day, some will turn out to be heavy and thundery with help mixed in, early slow moving because winds will be light. disappointing temperatures for the time of year, ranging from about eight to 12 or 13 degrees across on your spots in the south.

yesterday, the deputy chief medical officer for england, jonathan van tam, said the decision to offer the astrazeneca vaccine was a course correction, but not about stopping or delaying jabs. vaccines continue to be the way out for the uk. they continue to be the way in which we can get our lives back to normal, and our economy opened up again in the shortest time possible. so the message remains clear — everybody who has already had a first dose of the astrazeneca vaccine should receive a second dose of the same brand, except for the very small number who experienced blood clots after their first vaccination. those who advise the government on vaccines want us all to understand the subtleties of risk in medicine. even aspirin, for example, has an incredibly rare condition — which is fatal in children — occasionally associated with it. so these things... they're not unusual. the risk balance is something we have to communicate because it is a little... sometimes a little difficult to get that concept across accurately. questions remain, however, about what this modified advice will do

nonetheless, paul, do you| reckon their remarks by professor jonathan van tam, the deputy chief medicalthe bottom at the moment in terms of the bottom at the moment in terms of the level of disease in the uk. i think the wasn't as big in terms of a big increase in transmission, because essentially, meeting out—of—doors is associated with a fairly low risk of transmission, the big challenge is going to be the next step which is currently scheduled for the 17th of may, and i can see no evidence that that will change of the moment, but certainly, i think that is going to be the big challenge, and how we manage that gentile that impacts the epidemic as it is. and we know that towards the end of next month. in it is. and we know that towards the end of next month.— it is. and we know that towards the end of next month. in terms of apps from that effectively _ end of next month. in terms of apps from that effectively allows - end of next month. in terms of apps from that effectively allows people | from that effectively allows people to meet indoors, again, the rule of six applies. what is it

professorjonathan professor jonathan van tam professorjonathan van tam at that press conference it littleson, an immunologist at cambridge university. gentleman, think you very much for joining us. we will crack on street away, because we have an awful lot of interest in this and a lot of questions, so professor robin, i'm going to come to you first. claire is asking if you are under 30 and have had the first dose of astrazeneca, what should you do? should you have the second dose? yes, she should definitely go ahead and have the second dose, that is what is recommended at the moment, and so far we have no recorded cases of this type of blood clot with the second dose of the astrazeneca vaccine. it does not mean it completely removes the risk, but it looks so far as of the risk may be lower, if you have had a first dose and not had an adverse event. and lower, if you have had a first dose and not had an adverse event. and in keein: in and not had an adverse event. and in keeping in line _ and not had an adverse event. and in keeping in line with _ and not had an adverse event. and in keep

so jonathan van tam they're talking about a course correction — is that how you see this move?correction - is that how you see this move? very much so. an important — how you see this move? very much so. an important point _ how you see this move? very much so. an important point made _ how you see this move? very much so. an important point made by _ how you see this move? very much so. an important point made by professorl an important point made by professor rain is that all affected medicines are recognised to have some side effects. that has to be put into context, for example, women will take the contraceptive pill out of choice to prevent pregnancy, and there is a 1% risk of a deep vein thrombosis over ten years. but if they get pregnant, there's a massively increased risk of deep vein thrombosis. so there you have a commonly used medicine people take out of choice which reduces just risk of pregnancy and reduce vein thrombosis. risk of pregnancy and reduce vein thrombosis-_ risk of pregnancy and reduce vein thrombosis. ~ ., ., ., thrombosis. when women go on the ill, th

got his mask on, naturally and that is being administered by the deputy chief medical officer, jonathan van tam his first vaccination. now it's time for a look at the weather with carol kirkwood. hello again. the next few days the forecast is one of sunshine and showers, chilly by day and chilly by night. today we've got that mixture of sunshine and showers, many of us, of course, will miss the showers. they could be wintry across the tops of the mountains in scotland and it's going to be a brighter day across southern england and wales than it was yesterday. these white circles represent the average wind speeds so it's not a particular windy day, but the direction is important and once again along this north sea coastline it will feel cool in the north—easterly wind. top temperature's likely to be between 11 and may be 13 degrees. through this evening and overnight, many of the showers will fade, but not all of them and under clear skies it's going to be cold enough once again for a widespread frost. these temperatures that you can see here represent towns and cities. so over the next few days

yesterday, the deputy chief medical officer for england, jonathan van—tam, said the decision to offerative to the astrazeneca vaccine was a course correction, but not about stopping or delaying. vaccines continue to be the way out for the uk. they continue to be the way in which we can get our lives back to normal, and our economy opened up again in the shortest time possible. so the message remains clear — everybody who has already had a first dose of the astrazeneca vaccine should receive a second dose of the same brand, except for the very small number who experience blood clots after their first vaccination. those who advise the government on vaccines want us all to understand the subtleties of risk in medicine. even aspirin, for example, has an incredibly rare condition — which is fatal in children — occasionally associated with it. so these things are... they're not unusual. the risk balance is something we have to communicate because it is a little... sometimes a little difficult to get that concept across accurately. questions remain, however, about what this modified advice w