british chemist joseph priestley discovered nitrous oxide or laughing gas means really on time.is a lot of pain, but it was not possible to use it normally for obvious reasons at about the same time, too, british scientists edward stone was investigating the effectiveness of willow carabine extract, but only 100 years later. this tool began to be used everywhere and in 1824 the substance salicylate was isolated from it and this became it. the birth of the first painkillers, the first synthetic anesthetic drug was finazon, discovered in the 1860s in 1893 by scientists discover pyramidon, which at that time became the gold standard in anesthesiology, and in the 20th century it was replaced by acetylsalicylic acid. true, this popular drug has side effects that the gastrointestinal tract does not like, i will add that investigators are still working on the ideal formula of analgesics that could relieve pain and not cause adverse reactions. and in order to understand why i propose to understand, the very mechanism of occurrence and more, and this will confidently help us, a learned p