one year, a texan, karen silkwood. >> streep: let's not fight. >> safer: the next, danish in "out of bror has asked me for a divorce. he has found someone that he wants to marry. >> safer: she wore spandex for "mamma mia," a nun's habit for "doubt," and a beard, playing a rabbi in "angels in america." >> streep: it always really bothers me when people imagine that characters that don't look like you, or have the same accent as you do, are far from you. the great actress sybil thorndike said, "i think we all have the germ of every other person inside of us." and i think we do. >> baroness thatcher, how are you feeling? >> safer: margaret thatcher is 86 now. her daughter carol has written openly about her mother's slide into the darkness of dementia. the film tackles the issue head on. did you have any concerns about showing this once remarkably vital woman having lost it all? >> streep: well, that was the part that most intrigued me. first of all, i don't... i don't feel there's any shame in dementia, in people that suffer it. >> and you're not prime minister anymore. >> streep: to te