you can find the mutation and mike kollek did this and he took a tumor which really response to anything and found the mutation that was unique to that particular cancer and engineered the t cell to respond to it and kill it. they got responses that no one has ever seen with that particular kind of cancer. that is very personalized medicine because you have to take the tumor you have to seek sequence the genome, you have to have very suspicious sophisticated laboratories to do it. i think as time goes on i'll be widely available. >> when less quick question, so has the cancer act performed its mandate in are we winning the war. >> to support research, about 70% 100,000,000,000 dollars went into basic laboratory research. when i went in with mary she would ask that she was am going to ask a 200,000,000 dollars above the president's budget. i said merry there's nothing i can say that could justify it and she said don't worry i'll only get half. sure enough, we could have. 5,000,000 of it would go into the area i talked about, 95 we going to laboratory research which is fine and the way it