the problem is the theory of kristi auger free is very well defined and developed, it's elegant. but the theory of crystallization, the physics of how molecules can come togethe together -- >> getting a signal and changing heavy metals. , the physics of how to coax a particular molecule without knowing it structure and even if you know it structure, if you give somebody a structure of a molecule answer i want to to predict and what condition this will crystallize. they won't be able to do it. so the physics of what happens to persuade molecules to stack up in a very regular array is a complex and undefined and so likely what we do now, we don't set up thousands of conditions by hand, we have robots. and we now even have robots to screen crystallization conditions so it's still a hit or miss random process. >> so that brings up an obvious question, what is the future of crystallography and is everything becoming cry mom cry. even in 1985 richard henderson had written a paper showing that audit be possible for atomic structures from electrons. a few people at the time actually beli