laurie glimcher is president and ceo. doctor, thank you very much for joining us today >> my pleasure, becky. >> senator john mccain's battle with brain cancer has brought a new focus not only on his disease, but cancer in general where do we stand right now in innovative treatments? >> we have huge progress for innovative treatments in many cancers, including at dana-farber, which is a very difficult cancer for example, we have several clinical trials now in progress, one of them is an immunotherapy with initially promising results. >> immunotherapy sounds amazing with some of the advances that have been made, but why is it that it tends to work on some tumors, not others, and works on some patients, but not others? >> if we knew the answer to that, we'd be able to treat all of our patients. there are some tumors that are immuno responsive and there are others that prove to be resistant like ovarian cancer and pancreatic cancer, but there are some patients that have responded to immunotherapy and we need to do a lot more