lyudmila will die, this is the main complication in which we must be prepared doctors to operate lyudmila will be a very famous doctor. he has the greatest experience in russia in removing the most difficult adrenal tumors. the only surgeon who operates on this gland with a special method. pay attention to the patient lying on her stomach , legs bent at the knees, this is the shortest way to the adrenal gland. the back hurts less than the stomach. the operation will last an hour and a half. you know, i specifically left the operating room because what the doctor just said about pain, and he said that if the incision on the back pain is felt less, this is a very, very important fact. and i can stop you a little. you are a nurse and operating unit. yes? let us give you what we want ask so why does back pain feel less than pain. uh, for example, on the stomach or on the arm, i will conduct such an experiment with your help. here are two regular injection needles. and if, for example, i take two of these needles and ask you to say with your eyes closed, do you feel two needles or one , should you give me two injections or one? one here, a person feels very small distances, because the receptors are located very, very close, and now we look at the sensations on the back. one or two distances a person no longer feels, and our incision is less than three centimeters, therefore, even in such a situation, there are more postoperative in the scar. maybe not. thank you so much for these extraordinary details that play a huge role in the lives of patients. we will break for a while, but let's continue talking about endocrine tumors, tumors that can radically change a person's life at the very end of the program. therefore, the health program begins necessarily. wait for its completion while in this life severe endless passion wake up in the morning stay healthy health is with you again, dear friends. our program started in st. petersburg. we were in the high-tech clinic of st. petersburg medical university. today. at the very end of the program. we will return to the topic of endocrine tumors, but it must be said in general that endocrine tumors are special tumors . actually, like endocrine organs, because endocrine organs produce hormones , tumors can produce too many hormones. and, of course, it changes a person's life, so today we will return to operating clinic, high-tech, we'll see. what miracles do doctors perform? in the meantime , the health program begins. and as always in our program, there is one single rule: only the best doctors in russia and the world work here in the television clinic of the health program. hemorrhoid cream is the best face cream cosmetic tricks that get rid of dark circles under the eyes and wrinkles. this is up to you if the shoulder joint does not work. it can be replaced with a nail unique endoprosthesis technology is used in the hospital named after botkin, sweetness or nastiness , the answer was found. why do we love sweets so much and why is it not necessary to give up sweets? do you know start this program? we want a completely unusual theme. i really love. uh, when it becomes known that some creams that were not intended for the face, someone uses for the face, whether it is reasonable or unreasonable in general, everything is very interesting, because i myself, uh, for example, consider the best moisturizer for the face cream with urea for feet, because there 20% is absolutely proven in urea substances are known, how many molecules it holds on the skin urea is in our skin, that is, this is such an absolute physiology. and since the legs are 10 times drier than the face, these urea creams were very actively used in diabetes. and now i think that there is no better face cream than a cream with urea 20% or more. what was my shock when it turned out that i was in my knowledge of mechanisms. the action and preparations of active ingredients and creams have been overtaken by a variety of women in russia and beyond. abroad, because it turned out that now a huge number of women use the cream for hemorrhoids. you yourself understand what place it is intended for, so they use a cream for the treatment of hemorrhoids as a cream for solving a variety of problems on the face. elena yakovleva saves her face from swelling with an ointment for hemorrhoids. this is the beauty of sandra bullock from wrinkles under the eyes of a hemorrhoid cream case, smears a hemorrhoid cream on her face. it seemed to me, in general, so interesting and funny that i looked at the cream for hemorrhoids in any way at the cream for hemorrhoids, when there is inflammation is pain. and there is swelling, and i looked. can this hemorrhoid cream really be used on the face? and if yes, then in what cases is it most amazing that we found a simple russian woman, she is nissanra bulok and not elena yakovleva tell me how you use the cream for hemorrhoids, and how it helps you read, and first began to use the cream on the internet somehow imperceptibly, but at the end of the month, the effect was no longer long in coming. and what effect did you get? i had very dry skin under my eyes t-zone knife and under my lips, right here the skin became soft, noticed that small mimic wrinkles around the eyes disappeared. and very satisfied. so in general, as they say, we must understand. we have a lot of creams here, there are really a lot of them for hemorrhoids, so the most important thing is to understand what components can work there, because in russia a lot is registered and all sorts of nonsense there with some herbs with some daisies. this is all nonsense, but there are three active ingredients in the hemorrhoid cream. here is their presence. you should find in this very cream. the first phenylephrine is a substance that spasms the vessels when it may be needed. when you have dark circles under the eyes or the vascular network is visible on the face , the vessels spasm and disappear. there were so many times creams hemorrhoids did, like this the following cream for the treatment of hemorrhoids may contain the steroid hormone hydrocortisone how it works it relieves inflammation, so most likely your dryness was associated with inflammation of the skin and this inflammation medication removed moreover, inflammation is always swelling cream with hydrocortisone will relieve swelling skin redness too. in general, as they say in that place, that the effect on the face will be the same, and finally, the third component that can be included in hemorrhoid creams. this is a local pineapple, which is called lidocaine in cosmetology. we use these creams with sledocoin, we constantly use these pain-relieving creams that the essence applies to the face worked up to the knee. it consists in the fact that it blocks the transmission of a nerve impulse, and all of ours. this nerve impulse causes the muscle to contract, so cosmetologists never do anesthesia. before the introduction of botulinum toxin, they need wrinkles to remain in order to see these wrinkles, because the cream with the local monastic smoothes the face and wrinkles are not visible, so the resume turned out to be a decongestant . there are antispasmodic, vasoconstricting agents and there are anti-wrinkle agents. in the case of hemorrhoid cream, this is a proven effect, because it is a drug, therefore , in fact, why is there no medicine is always better than cosmetics, because cosmetics never penetrates into the lower dermis, the drug penetrates everywhere in this medicinal day. so to be honest, for me. it is directly revelation but these creams can be effective and here now there is a question. can there be any harm from the cream, vessels narrowing with hydrocortisone and traces of cocaine. what do you think? i think not. i haven't noticed any changes in myself. you know it can be dangerous, of course. everyone has a medicine, indications , contraindications and doses. the first is all the creams that will all the time narrow narrow narrow vessels sooner or later this will lead to a change in the quality of the skin, because you don't like the way the dilated vessels look, but the skin receives blood flow. this is the first, the second hydrocortisone is a steroid hormone or other steroid hormones that relieve inflammation and work great for hemorrhoids and on the face with constant use will cause skin atrophy, the skin will become thinner and look bad and lidycaine. here lida, of course, from my point of view, will not bring much harm, but it will straighten wrinkles for the duration of the cream, this is several hours, therefore, if talk about my medical advice, then the first thing when choosing creams. see what's included. in terms of swelling under the eyes. so you have to choose. banal substances and vasoconstrictors, and the second one can be emergency help. you see, such hemorrhoids with hemorrhoids cream are emergency help. urgently. they applied beauty somewhere and struck everything all the time, as we use cosmetics, creams for hemorrhoids on the face cannot be used, but in general this is an amazing idea that someone came up with. so let's take a break for a while, and then let's continue. awakening is possible for this are given such tests? 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and if fibrosis is added to prostatitis , it’s even harder, the smart enzyme longidaza helps to reduce inflammation and break down fibrosis foci so that the symptoms do not turn longidasa’s life just against fibrosis with prostatitis, the recommended course is two packs into the esophagus. he knows that if there are no direct symptoms, colds, fever, runny nose, cough and the voice is gone, it is unlikely that it is a cold, and it doesn’t hurt from petropavlovsk-kamchatsky. then i came a long time ago, i was then 8 years old, when we moved, my parents moved something else to do. we will reach the end. my parents brought me, when i was 8 years old, and actually. since that time, i have never had it again. i left the city, kemerovo, mm, right after the medical institute. i returned there a million times, my parents lived there, then we moved our parents, so we are provincials, conquering the mask in the capital, i want to say, you are only good these. okay, how old are you? i am 25, not a single injection in the face. no, no, i don't have any tattoos. interveners, very strongly. i'm afraid of all this. glory to the parents of this sweet girl, how well they are her parents, it turns out that right there my mother works with me and monitors star disease. watch your health , watch your money. and this person is never one hundred percent. i always go to our guests during the commercial break , they will tell you in full what your indicators are, and then i’ll wait with my mother at our studio. okay, see you. what a joint with you again health, dear friends, we will talk about this complex joint, because it is formed from three bones at once. and now you can feel the clavicle on these bones, touch all the clavicle further directly to the humerus. here it is behind the shoulder blade, three bones form this joint. now imagine that something is happening in a person’s life and this joint is being destroyed, move now with this joint, and it moves almost 360 ° makes any movements what happened to you. why did the joint stop working? what was most dramatic was the device itself was that when e composition was not very sick and went to the doctor. it turned out that there was no need to treat anything, that it was only necessary to change the joint. i did not apply to the botkin hospital. there i was told no. no. you are our patient, that everything is really exactly like that, that you need to change the joint and get a quota. i was quietly operated on by them, that is , in the absence of some kind of bright pain syndrome, everything collapsed. yes, yes, what's wrong with you? well, the pains were such that it really was no longer possible to endure - this is not to care it’s impossible not to wash yourself, not comb your hair. that is, not to dress yourself, it was already really impossible for you to get sick. yes, very key joints and then not the same turned to the doctors, they replaced one at the beginning, yes, and then over time. yes, we rarely talk about shoulder replacements, usually the hip or knee is in the lead. well, such situations also happen and you should know how to catch yourself in time, we go to the operating room, votkinsk . on the operating table, a woman whose shoulder joint was completely destroyed, and we see a picture on the gas-ringed fracture of her head of the left shoulder of the formation of a false joint, the lack of range of motion, both actively and passively against the background, preserving the only way to save a woman from suffering is to replace the destroyed joint with new artificial. this is how it now looks on the surgical table for a few days, it was made ago. here in the botkin hospital. by special technology based on computed tomography 3d model they designed and then 3d printed the mold, and then cast the new joint as a sculpture from titanium. this is a very precise design that should fit perfectly into place. while we pre-check the movement. left going nowhere. everything is stable , you can proceed to implantation, before our eyes, surgeons knead bone cement. this solution will firmly fix the leg of the endoprosthesis. inside the bone canal. the whole design of the 3d prosthesis stem head liner, like molded, snap into place. everything, the prosthesis is installed, we check the volume again movement. everything is completely stable. nothing to open i see loose leaves going on. this story about the operation, i want you dear ladies to move your key joints, show me. and with the second hand, but i almost returned, i can do it like this, but before i couldn’t no, that is, it was unrealistic to fasten the bra now, right? okay. so well, this is the first one, which is in the nineteenth year. and this is literally 2 months. that is, until the doctor’s movement volume rises above this level movement will be restored. here, just before the postoperative period of 2 months , patients after the operation are sent for rehabilitation. i am not taking the full course. here. well, then it depends on the patient how much she herself will work in order to see the volume of movement. you are aphids, your hand rises, like this or not. it depends only on one person, personally on you. i want to introduce you to the doctors who are sitting next to me professor murylev runs the moscow endoprosthetics center, which is located in votkinsk hospital and, gennady gennadyevich rubin, a brilliant operating surgeon , a professor is also an operating surgeon, that is, around me these are not operating surgeries. these are our favorite characters. so, as far as i understand, the situation is such that you can put a conventional endoprosthesis. here they are, we have a variety of goodness and replace some non-working parts of the shoulder and you can individually make an endoprosthesis for the patient individually correctly . correctly, this is the case in this court, but who can come to the botkin hospital? can it be free it is possible, if you are not muscovites to live and live in russia for free . they are included in the budget program, and will be made free of charge. what joints can be replaced for free at the botkin hospital for him muscovites, because for muscovites everything is free. this is understandable, as they will enter the chi program as soon as they enter, then, in principle, immediately. accordingly, we can do all this. i just want to explain to the audience, very often you say why are we paying? why are we paying? in principle, you must understand that this is not growing on a branch. this is bought either by the state, then this system of compulsory health insurance is compulsory, or by a person, there is no option for muscovites, shoulder joints are already free for muscovites anyway . russia so that for russia it is also free of charge federal centers, this is also done free of charge, how quickly you recovered each of you, but 4 months. well, i was promised 4 months. and, well, it was a stupendous job. you have one hand rises well, the other has not yet passed. this four-month period is to work properly to work, what do you say you are a wonderful doctor. this is generally a chic department, where not a single doctor is, let's say so bad, all the doctors with a capital letter are huge to them. thank you dear doctors my top class professionals. keep it up , there's nothing more to say, we'll come back for a while, and then we'll continue. three chords of the new season , see after the evening news pentalgin is the number one remedy for pain, spasm and inflammation in headaches and other types of pain pentalgin we will do without pain ozone we offer with love 30% ingots for grandmother's baby food, a basket and a 57% discount for fresco instant coffee what is the best medicine for cystitis in terms of price not simple, alar, more profitable up to 50%, not simple, alar, treatment of cystitis without overpayments, sovcombank should you think about savings, as sovcombank offers an excellent interest on the deposit. and so. you skim the cream off him in the department and online. misha loves a scooter because he loves to bring people joy, and asya loves a scooter, because he loves when everything is on time, and in a scooter you can pay up to 99% of the order with a bonus from sberbank thank you sign in to the application with your sberbank id, save up bonuses and get a scooter discount to your heart like that. diclofenac-acase gel in a package with a man contains a maximum concentration of the active substance of 5%. 5% gel. diclofenac alternative quality patriotic has its own cyberweek only 17 to 31 january. buy a game set of defenda tuggies for only 1.000 290 rubles. sber mega market millions of people choose laxative fruit-based chewable tablets. try the new phytolax jujube berries just one at night for comfortable relief in the morning without causing cramps or bloating. where can i find you? i stopped. how did you get here, before you judge others, you need to figure it out with yourself. this pear is here in order to beat it this morning according to the horoscope, to insist on calmness for any. circumstances not deaf. what check do you need. yes, he’s joking, he presents the movie one tv, well, how was your benefit performance, the sea of flowers was wonderful, they were stolen too. i gave them to a friend. and what was the name of this friend alexander of health, dear friends, here i stand. i have this object and personifies. he tastes different flavors. and a general sense of taste. this is what we experience with you through the sense organ called the language of tastes. we have five sweet salty bitter. this coffee bean is sour and flavorful. mom, few people know what it is, we will definitely tell about it in the program, so. today we will talk about the taste called sweet taste. and there is such an interesting thing there are two tastes that our body is afraid of. it is a bitter taste and a sour bitterness that we feel in concentrations of less than 100,000 and parts per million. it is so important for us to feel bitterness early, because bitter substances are usually poisons, therefore, even in the vocabulary, even in the language, we have a designation that is not bitter, for example, bitter or bitter, and in fact. you know the millionths. we can feel a bitter taste and the body tells us, don't do it, maybe it's poison and generally bitter. we are not particularly interested in it takes a lot of sweets to feel this point and this point. that is, if we feel gorky in millionths, then we feel sweet in tenths of a gram, that is, it should be, as they say, sweet. truly the taste is quite unusual. why is he unusual what do you need to know about it? today we will talk with our wonderful guest, a young handsome already famous, who touched my mother's heart. this is a girl to the core, because she came to us with mom. why do i need the sun of monaco why do we say we have a center, when your look is bright in this sense, if you are not around and jazz art, and popularity came completely unexpected one day. in the evening, the girl posted a cover version of the song on the internet, and when she woke up in the morning she found that the number of subscribers had increased dramatically, happiness loves. i want autumn 2019 lucy presented her debut album to the audience. since then, her songs have been included in the first lines of the musical rybnikov married girls, and, according to her, her heart is not busy. that's what you say, so the girl's heart is not busy. she will come to you and tell you already busy. his name is yura lyusenka chebotina, dear visit us. well, when you look at these deeply sexy clips, i think now a girl with a head to toe tattoo will come to you. here comes such a well-worn one, this dear, dear child, who speaks to me when they meet. i came from mom. here is my mother, where is our beautiful mother anna yuryevna come to us, happiness is that she is still at the age when mother is so needed and so important. mom, well done. yes, she is my ceo, i apologize in advance. i'm sick, so the voice of no, we 're examining her today after the program. i think the problems there are completely different. yes , in a completely different way, and just to us you are engaged in concerts, advertising and everything. in general, all finances go through her mother, a professional accountant. and it's a better choice to have your own mother as an accountant why because mother dear lives in the interests of her child, nothing more absolutely true. well, the girls are one 25-25 the other. and we are no longer afraid of anything. luss us, what do we have to lose children have grown up, we believe that we are well done for raising them. we're not yura . we don't give five stars for this girl. she's not spoiled at all, really, but she's understandable as a girl, she's a beauty. and we are there on yuryevna , not really into another guy. so still nothing, but not for everyone it seems that at that age in my mother's. life is just beginning. we, too so we console ourselves with this phrase. well, you see, all the women took a loud move, they understood us, but look. i want to talk to you. that's what sweetie is about. this is what she loves so much. and you don't like it, she loves sweet, coffee is very sweet, i love it, because coffee is a bitter drink. it's a bitter taste. yes, we mask gorky's genetic intolerance with sweets, but probably, yes, therefore, yes, but at the same time i can't live without coffee. well, look, we will talk about the sweet taste. so this child is only adds to coffee, but wash with mom. oh, i love it. that's it, that's how we live, it's hard to limit ourselves. why because in nature, sweet has a seasonal appearance, and when a person was like an animal and did not live perfectly in houses, but wandered, he lived together with wildlife, then as soon as he met something sweet. he had to eat a lot. why because sweet is an energy that is both fast and it can turn into fat. hmm , that is, 1 g of sweetness gives 2 g of fat here too. here, well here, of course here is our theme in art, everyone gets better from carbohydrates. it's an illusion to think that weight gain comes from fat. that's from the water. yeah, well, well, as they say, we ate, but we didn’t run, we didn’t use up this glucose quickly, and that place begins to grow in us, which we have been trying to draw in for a long time, but then we wave our hand at this attempt. wow, there's nothing you can do. not only that, we have a drug addiction to sweets, but there is yuri, my dear. so everyone has it, but i have such a nature that we make our daughter. what to do? how can my mom and i lose weight i just she said that sweet, except coffee with sugar. i just don't like sweet. i can eat chocolate. but this, perhaps, was lucky there once a month, and now another generation of mothers who love everything that they do not like. i suggest my go to yoga or run. this is my worst sin. i can't play sports. but actually there is one more thing. the fact is that our brain cannot live without sweets. sweet is not only for the mind. sweet is not only in the direct . sweet is all cereals. it's all flour products. and it's vegetables and fruits vegetables - i also love cucumbers carbohydrates. these are also carbohydrates. well, carbohydrates that are difficult to break down, so we don’t need to break down fast carbohydrates, you’re full of high spirits and you happily live your brain, our brain doesn’t live without glucose. our task is to make him extract this sugar from vegetables at worst from fruits. well, okay, from cereals, but they are here and tk is theoretical. you can replace it with vegetables, of course, this is just fast carbohydrates. and he is generally vegetables - this is slow. no, for example, i ordered myself on sharp from vegetables. we always take the example of the truth. yes, as they say, it is easy to do all this is difficult, but we must try. what were the most difficult moments with the girls. she must be two girls. you are the youngest, the youngest, there is also the eldest daughter. she was a realtor, a difficult child. luska our monaco grew up. no , she was never difficult because she was always busy. she did not have time, she always ran to a music school with a music school for ballet, when she was called there in the entrance to drink beer. she says to me once. i can't show it to me. so here it is on the hand, where there is no clock. yes, we show the time. no, it was difficult at some moments with my mother and was it difficult to persuade my mother to become a partner in business , it was not difficult to go to bed. she helped me to go to concerts, helped me with the competition to go with me everywhere, and, as it were, decided some organizational issues, and then why look for someone. we've been together for so many years. she is already in the subject, she fumbles everything , understands what needs to be done and how did you give the poor girl to show business, maybe merciless merciless. i personally worry, because this is still such a world, quite cynical, you understand that you were created. here is such a kind of not spoiled, anna yuryevna i would use this word, not spoiled girl. this, in principle, is a miracle, well, yes, i found a business to merge. he believes to hold on. the most important thing is to choose the right environment, which will tell you in time somewhere wrong, what needs to be done, what to change and with whom to communicate, with whom not and the best environment. this mom is better. no it's us we say, honestly and frankly, and we take an oath once again, so that we will sharply reduce the sweetness less and go at least to yoga , at least just to see what they are doing. at least on foot, at least let's go, just start walking. that's how our sweet conversation turned into not the sweetest. finishing life with sweets, i want to say that if a person can simply refuse salt and live without salt, then we cannot refuse sweets, so the only advice is to extract sweets, in fact, not from the sweetness of straight sugar candies honey, honey - this is the same sugar or flour, and extract fruits and cereals from vegetables. hmm, then he and yuryevna will improve. what yes, what kind of vegetables to the resort, we go to the resort said, mom, i understood everything girl. what do you wish for yourself in life? i wish myself in life to finally tighten my legs , straighten up and said to lose weight. it was to say a more athletic physique to finally straighten his back and get rid of the problem of periodically losing voice. we were visiting the bottom today, just lovely , sweet, sweet, i don’t want to sit. can we let's go? no, we'll do anxious watching until we go to yoga anywhere. let's take a break and then we'll continue. three reasons to urgently get an mri of the head secret foods for good sleep. how old is your liver? and how to help her grow old the program live healthy in enlightens and helps everyone tomorrow on the first against pain there is askofen p, pain reliever with paracetamol at an affordable price ultra enhanced composition to combat migraine and other types of pain, what is the reason? hemorrhoids are a problem, it can be not only outside, but also in the veins, so it is important integrated approach integrated treatment of hemorrhoids from the outside and from the inside on yandex market cyberweek and up to 70%. buy lemongrass. in my art, i strive to recreate the plasticity of human movements, but, unfortunately, for dolls, the hinges are the weakest point, and i do not have artneo, thanks to the special collagen, the triple helix shape contributes to support. joint health artneo, five special components to protect the joints and spine in five links. all crusty perfectionists eat only grain pockets never use hormones growth and harmful additives. yes, these are high standards of eyelet eyelet pure products of harmless additives. what is the most cost-effective medicine for cystitis ? 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as you wish, each as it suits him. choose your payment method with the world payment system and the fast payment system. sugar or cholesterol jumps pressure on the price. when naobutin hurts somewhere here, it acts selectively on pain, spasm and violation of stool neobutin, when it hurts somewhere here, a pair of grant and a grant of three cheeses at an attractive price, only tasty and point amelotex gay acts exactly in the focus of pain by caring for the closest , the exact solution for free movement. dear friends, our program continues and i remind you that this morning the health program started in st. petersburg at the high technology clinic of st. petersburg state university, and there we encountered amazing doctors and a huge problem called endocrine tumors. i invite you to st. petersburg. let's remember how our program started. we are starting this program in st. petersburg. this is the famous eliseevsky grocery store in st. petersburg did not allow it to be closed. and here, according to rumors, the showcases of the work of the famous native of this city , mikhail shemyakin, i was at this exhibition when it was in st. petersburg, my children were still small. this is a carnival in st. petersburg. here are some quirks. long rat pups, or animals are not afraid, but they have frilly facial features, frilly noses, there are some features of the disease, which in the same way can change a person's personality beyond recognition. these are diseases of the endocrine system and happiness when next to you there are doctors who can help you. this is where we begin our conversation about endocrine tumors and about the doctors of st. petersburg who perform unique surgeries to an elevated world class. let's look at the shimyakin rats again. and this is a bearded woman with a bare chest, who is feeding a child. magdalena ventura, she also had an adrenal tumor. she was a celebrity of that time , modern doctors understand that tumors were not removed then and they had to live with them, and this is a goliath, whom i forgive and knocked down by a small home. giant goaf ingrown has also been associated with tumors of the pituitary gland, a small gland in the human brain that produces growth hormone. we don’t know what the goliath looked like, this is the invention of artists, but this is what people with a pituitary tumor look like today. compare with how they looked before the disease , catastrophic changes are caused by an excess of growth hormone, and these alpine nerds are not overweight, but with a lack of thyroid hormone, huge necks. this is a giant, thyroid gland and cretinism the consequences of hormone deficiency, of course, today all this is being treated. lyudmilae gland itself, which did not allow magdalena ventura to live . by chance, i went to take this lung, and it was found there. so there are kidneys. ah, a new development. so far, the tumor has not manifested itself in any way, but it must be removed. and this is a huge problem. the adrenal gland produces many hormones. these are male sex hormones, which so changed the appearance of magdalena ventura, and hormones that are much more important for life, which maintain blood pressure and if removing the tumor the doctor damages the adrenal gland, then the pressure can tragically fall and lyudmila will die. this is a major complication for which physicians must be prepared. ludmila will be operated on by a very famous doctor. he has the greatest experience in russia in removing the most complex tumors of the adrenal glands professor fedorov's morning for many years begins like this preoperative, so as not to lose his wedding ring during the operation. he takes it off and put it on a chain n