people that have pioneered it and john is the person who has experienced it. >> rose: let me turn to mary stein,-- murray stein, give me an overnight adding to what eric said and the prevalence of it. >> so as dr. kandel mentioned post traumatic stress disorder is very common in our military personnel who have been returning from iraq and afghanistan, and the rates, you heard, are up to one in five people with post traumatic stress disorder or depreltion, substance abuse, those all kind of travel together. but it's also very common in civilian life so in the u.s. general population, estimates of similar around 2 to 3% of people have post traumatic stress disorder in their lifetime. some people are more likely to develop ptsd because of their occupations. a lot of post traumatic stress disorder in firefighters, in policemen and women. and then as eric also mentioned, more ptsd in the general population in women than in men in large part because of the kinds of traumatic experiences women are often exposed to, domestic violence, sexual trauma and the like. >> rose: is the core here the fear, whet

joins me tonight to talk about his life, also joining me an extraordinary group of scien titss, mary stein from california san diego, lisa shin from tufts university, kerry russler from emory university, joann difede from cornell and my cohost is dr. eric kandel. a noubl lawyer yet, professor at columbia university and a howard hughes medical investigator. i am pleased to have all of them here this evening at this table. which gin we always do talking to eric kandel. what are we doing this evening. >> post traumatic stress disorder. this is a fascinating disorder. and it is unique in psychiatry. it is perhaps the only psychiatric disorder whose cause we really understand well. post traumatic stress disorder is a response to the physical threats to the integrity of one's self or someone else. it is associated with feeling of tremendous fear and helplessness. we are privileged thave john orien with us today who can tell us directly what it's like to experience post traumatic stress disorder. as you pointed out he's an american hero. he just retired from being litenant colonel in the army. an