lang was a consultant for merck in 2008 prior to merck submitting its pas. what dr. lang says is that surely by that time, mark would have had enough information to an adequate warning about the atypical femoral fractures. justice gorsuch: let's say i buy at least part of what you are selling, for purposes of this question, that the complete response letter and -- what is doesn't -- thank you -- doesn't completely answer our question. we have the march 2010 safety statement from the fda, which pretty quickly says they don't think there is science enough to support a causal link between the drug and the atypical femoral fractures. whatever was missing in the complete response letter from the fda seems to come in march of 2010. why shouldn't we read the complete response letter in 2010 letter?march mr. frederick: we are getting into the agency musings of the type that justice thomas eloquently wrote about, that it is not impossible for the manufacturer to have done the right thing. justice gorsuch: we will not dispute the elegance of justice thomas's opinion. [laughter

the risk merck warned about was low energy fractures at 746 merck explains to the fda how it was using the term stress fractures and it explains to the fda the term stress fracture included the very same kinds of things respondents are concerned about stress and complete all kinds of low energy fractures. >> but if i understand the terminology insufficiency fractures essentially there is a world you can have a traumatic incident leading to a fracture than others that are not but the fractures that are not caused by trauma that our small fractures or stress fractures to take care of themselves in large fractures now a bonus popping out the wrong way. those are really different things and caused by something that is not trauma one is an inconvenience and the other is a serious injury. >> a serious injury complete fracture that begins like a stress fracture progressing to completion so what merck was trying to do is explain if somebody complains about the pain that could be consistent with a stress fracture doctors ought to figure out what it is causing that if you rule out those typical

merck is a manufacturer. it has a duty to ensure that it shows are either safe or add yacht warnings are given when it's not. shouldn't you include trying everything possible including the corrections you were told to make including doing what the task force did, telling the fda you're wrong. america said i just have to let them figure out what to do. it seems to be sort of turning responsibility on its head. >> as you say, an important feature of the statutory and regulatory scheme is while the manufacturer has responsibility for the label it can make changes only with fda -- >> not true. it can make the change itself. >> that's true. it is to warnings and precautions is not simply that it regards the warnings as unnecessary. fda expressed a concern about the effects of over warning. if a label contained information about every possible health risk or every bad thing that ever happened to a person that used a drug people may be deterred from that. the wordings tend to get drowned out. >> what about manufactu

that is easy, merck doesn't change its label and there can't be a suit against merck. suppose the fda, i understood this to be your point, had said the real problem with your label is your talking stress factors and we think the issue is these major fractures and that is why we are rejecting it and we continue to consider the possibility of major fractures would if the fda had said that clearly merck is not off the hook. would you agree with that? >> with this caveat, that you would expect the letter given the documentation in merck's submission included a lot of information about more serious fractures even if fda was concerned about the wording of the label you would expect to express a view one way or the other whether there was sufficient evidence. >> it doesn't know yet let's assume. this is something it doesn't know yet. and it is rejecting the letter for another reason. you might expect fda would continue to work with merck about the major fractures, might expect a lot of things but the only thing the fda has told merck is we don't like this label about stress f

merck. merck, the pharmaceutical saw shares slammed today, down 3%.s part of the rotation out of the safety stocks. >> sell, sell, sell, sell, sell, sell >> and into the big semiconductor and tech stocks. >> buy, buy, buy, buy, buy, buy! >> merck has been an amazing long-term performer. over the past decade the stock has nearly tripled it's rallied even though the s&p is down. the source of its strength, wall street has gone gaga for key trude da, which has been wracking up incredible sales growth, especially as a treatment for lung cancer. plus, if you're worried about a global slowing economy or even if the government shutdown keeps dragging on, merck is exactly kind of company that investors circle the wagons around because it doesn't need a good economy, it's not worried about chinese trade talks to make the numbers. however, even though merck ran up dramatically last year, i think the stock remains way too cheap. and as the rotation plays out, it could get even cheaper, meaning you could get an even better buying opportunity. we're talking about

announcer: the supreme court oral argument in merck sharp and dohme corp. v albrecht. it concerns whether a pharmaceutical company can be sued in state court after the fda rejects the risk label. this is about an hour and five minutes. >> we will hear argument first this morning in case 17 to 90, merck sharp and dohm

good news for merck and how about holder's there from congo a boost. in frankfurt thank you. mexico's president has announced a series of social programs for poor communities which he says will stop people from stealing fuel fuel theft is a common problem in mexico and dozens of people were killed in a pipeline explosion last week. this was the aftermath of last week's deadly explosion in the state of pitt algo in central mexico. it occurred after hundreds of people rushed to collect gasoline gushing from a pipeline ruptured by suspected thieves thank you it's hard to imagine a more devastating representation of the country's fuel crisis. mexico's president lopez obrador swept to power on the promise to crack down on years of fuel theft which he says have cost the country billions of dollars in lost revenue. but his decision to close pipelines topped by criminals led to shortages and long lines at gas stations across the country. despite the crisis oprah door received a warm reception in the town of our company in the state of mexico where he announced an almost ten million d

putting a cap on drug prices joining me is ceo of merck ken frazier, great to see you. >> always goodtion how do we get drug prices hire? you feel if you put caps on things going to stymie innovation is that right. >> that is absolutely correct. let me start by saying, we want to work with the administration, and congress both parties, to ensure that patients can have meaningful access to destruction about affordability is a problem, the question is how do we solve the problem with day's patients without creating a problem in terms of developing new drugs for alzheimer's disease other things tomorrow's patients need. >> i totally agree how are you going to get somebody to put their own capital on the line to pay for, research and development, of new drugs if they think at the end of the day they are not going to make money on. >> it that is absolutely right, i mean we have to ask people to put a lot of capital up high risk for long periods of time there are ways we can go about it i think working on the affordability issue, without importing price controls from other countries. >> how

just shelled out $74 million to by celgene, and they wouldn't have done something so radical if mercken't winning head to head trials against them yut cetruda is taking names. you'll hear it's got a rock solid balance sheet, and like proctor & gamble, it's a fabulous slowdown stock. you have my blessing to buy this in weakness even though we have the powell pow rally mcdonald's up in the fourth quarter. i'm loving it. i believe mcdonald's is about to become a terrific technology company now that they can pick and choose what works in locations all around the world it's like a giant laboratory for him. before this guy took the reins mcdonald's struggles he's a compelling figure and once again, this is exactly the kind of company that is thrive in a softer economy so you now keep thinking about powell keep thinking about powell he should have been thinking, uh-oh, p&g, uh-oh, merck, and uh-oh, mcdonald's. but this was the real tell verizon. okay, i personally am tired of verizon going higher it gained 5% last quarter. i bet it has more upside it has a 4.3% dividend yield i expect the st

it tells me merck is the winner. i think that merck goes back and yields aumt three percent.er is the winner because they are the defacto new cancer drug. that's why bristol had to do what they did. >> our friends at quaalcomm would like you to focus once again as they always would on the continuing patent dispute, royalty payments dispute that they have. dispute is putting it mildly. do you think this puts more pressure on apple to settle there and the impact at all? quaalcomm didn't post the bonds. you have the continuing question in china about the ability of them to sell, unclear whether that had any impact here. >> i think that at this time, if you are apple, you need every friend you can get. i know that there is no love lost. i know they are about to go to court. if they want their stock to go higher and they want principle to prevail then there is nothing wrong with that. apple will be under pressure and quaalcomm won't be. quaalcomm seems to be winning. >> so i don't want to own semi conductors other than nvidia and broad com. it moved away from cell phones. it is so

this week the supreme court heard oral argument in the case merck vs. albrecht. when the federal food and drug administration rejects their label. in this case the fda did not approve of a

last few years, they have become more focussed turning into an anti-cancer premiere company, until merckame up with their drug. i think it's still debated for various cancers, but it did take bristol by surprise. since then, they've been trying to expand their pipeline, but to no avail so bmi decided to go for celgene, and that's been a once great growth juggernaut, can we call it that celgene is great, and it was based on a cancer drug choice, and celgene has been able to raise its price regularly. the problem is, the drug is going to lose its pat protection but because of the peculiar nature of the pharma business, we didn't be sure when it will go off the cliff the company made now what looks to be a disastrous acquisition of $72 billion years ago i thought it would be good they had a drug for irritable bowl indresyndrome, but it's inconclusive bristol-myers and celgene decided to combine forces. when i discussed this, after their many failed attempts, perhaps these are two drunken sailors holding each other up. i think maybe they aren't drunk but have fallen or hard times. if you own

at the same time merck does not pound its chest. merck is not that kind of company.rck want to give false hope to people who have cancer, which i think is right, having lost my mom to cancer i didn't want false hope nobody should get false hope frazier gets that. i think that this is a good sign david, we have to talk transports for a second. totally overlooked yesterday >> okay. >> delta reported a number that wasn't that bad. >> wasn't that bad, though it did take the airline sector down yesterday. >> right that has to do with the negativity of this market. >> yes >> marriott down bad travel and leisure, we lose travel and leisure, even though delta was principally international. if we lose travel and leisure, i come back to who is the fed -- what is the fed targeting? yes, they want -- they want fewer jobs it's just not what they can say. >> they don't want fewer jobs. >> they're using the phillips curve. they should get a phillips screwdriver. i will buy them all phillips screwdrivers, so they understand what phillips is. >> you mentioned marriott. remember when

i love that toni braxton i picked pfizer, how about merck, too this thing is going higher >>er with notecessarily saying the banks are in an environment they should be kicking you know what, bac out in a couple days get there. >> this remix is awful >> i'm very much in tim's camp jpmorgan tomorrow, we will get to see the cream of the crop and deserved a premium evaluation and doesn't have one jamie dimon. >>> i think you sell the whole group if banks are higher tomorrow i like cathie's strategy >> that's fitor us. enjoy toni braxton and the remix. "mad money" starts right now i'm just trying to save you money. my job isn't just to entertain but to teach you call me at 1-800-743-cnbc. or tweet me @jimcramer are we in a situation, a situation where the only thing we have to fear is fear itself

keytruda, from merck.re fda-approved uses for advanced lung cancer than any other immunotherapy. mac there's fewer government leaders here which meant there are many more business leaders and a focus on business. that was good. we talked about the economy where we were. second an economic slowdown was coming. just how steep it is ranged greatly. some, like ray said a recession could happen in 2020. he thought become a slowdown would not be able to raise rates at all this year. maybe even change the balance sheet. where did this recession idea come from. most were focused on issues like china and brexit. another key take away, china wants a deal. it will open up its markets to foreigners. they are seeing a better situation versus a few years ago. i bet we will see a china u.s. steel sooner rather than later. most important it will include foreigners having a chance to own their own companies in chi china. that's a huge deal given the population of china. also i observed artificial intelligence. these are re

keytruda, from merck.ancer than any other immunotherapy. (vo) ♪ here's a question. was it necessary to create a luxury car more teched out than silicon valley? with a cockpit fit for aspaceship. hang on. radar that senses things the human eye can't. busted. and the ability to make a thousand decisions before you even make one. was all this, really necessary? what do you think? ♪ mac there's fewer government leaders here which meant there are many more business leaders and a focus on business. that was good. we talked about the economy where we were. second an economic slowdown was coming. just how steep it is ranged greatly. some, like ray said a recession could happen in 2020. he thought become a slowdown would not be able to raise rates at all this year. maybe even change the balance sheet. where did this recession idea come from. most were focused on issues like china and brexit. another key take away, china wants a deal. it will open up its markets to foreigners. they are seeing a better situation vers

keytruda, from merck.ith more fda-approved uses for advanced lung cancer than any other immunotherapy. i've always been amazed and still going for my best, even though i live with a higher risk of stroke due to afib not caused by a heart valve problem. so if there's a better treatment than warfarin... i want that too. eliquis. eliquis is proven to reduce stroke risk better than warfarin. plus has significantly less major bleeding than warfarin. eliquis is fda-approved and has both. what's next? reeling in a nice one. don't stop taking eliquis unless your doctor tells you to, as stopping increases your risk of having a stroke. eliquis can cause serious and in rare cases fatal bleeding. don't take eliquis if you have an artificial heart valve or abnormal bleeding. while taking eliquis, you may bruise more easily and it may take longer than usual for any bleeding to stop. seek immediate medical care for sudden sign of bleeding, like unusual bruising. eliquis may increase your bleeding risk if you take certain

merck and pfizer really were the outstanding stars.y are at the top of the dow and that's in the case of merck driven by a very, very important drug, keytruda which grew and grew very nicely in cancer, and pfizer had a very good drug for breast cancer and autoimmune diseases so invanovation is the story gon forward as well. in 2018 the script for the pharmacy was written in that fda approved 59 new molecular entities that is double the average over the last ten years it's a fantastic run rate. this innovation is going to show itself in a very special way in 2019 so in spite of the volatility that you're seeing in a lot of other sectors, the pharmaceutical sector, besides being a defensive sector, is going to benefit from this innovation flow. >> of course one of the big questions will be how you price that innovation, right, fred you had the story in "the wall street journal" today dozens of drug makers raising prices on hundreds of medicines to start off the new year what happened to all these freezes and moves to reduce drug prices h

while bmo downgraded merck to market perform says competitors to the keytruda cancer treatment could be launching their own trial soon. >>> up next, the russian who manages his country's huge sovereign wealth fund says u.s. sanctions on his nation and its oligarchs will hurt america more than they hurt moscow. is that truth or propaganda? come on. up next, we put that question to the sanctioned oligarch often called putin's banker. andry kostin is next from davos, switzerland when "countdown" comes right back. great news, liberty mutual customizes- uh uh - i deliver the news around here. ♪ sources say liberty mutual customizes your car insurance, so you only pay for what you need. over to you, logo. ♪ liberty. liberty. liberty. liberty. ♪ from capital one.nd i switched to the spark cash card i earn unlimited 2% cash back on everything i buy. and last year, i earned $36,000 in cash back. which i used to offer health insurance to my employees. what's in your wallet? i am a techie dad.n. i believe the best technology should feel effortless. like magic. at comcast, it's my job to develop

merck and pfizer both downgrade from analysts. said they are facing a potential cliff for patents. pfizer over expectations for keytruda. for the weekly leaders on s&p 500, tcg, california fire protection group, it was private electric system caused fire. not on the shoulders of pg&e. big chip reports this week as well. back to you. liz: thank you, gerri. thank you. i want to bring in a name known for many years on wall street, ralph al acampora. let's spin it forward to the rest of the quarter, bring in news about federal reserve maybe halting drawdown of federal reserve balance sheet. what does that mean for stocks? >> i think the market is trying to tell us something, liz. the strength in face of all the negative news, whether it is china, whether the shutdown, the government shutdown, et cetera, the market is holding up well. i think it is telling us it wants to move higher. liz: it is moving higher at the moment. all this talk about recession possibly coming. i'm not an economist. i don't see that with the data. i do see mayb

a country the size of brazil cannot be tied to merck is sore for its trade.e need to be free and make eye lateral agreements. whatever the agreement, there will be restrictions suggested by france. we have reached an impasse which will not be cleared up quickly. >> i have talked to a lot of business people. there is a great enthusiasm for your administration. you also cause difficulties for business people here for various reasons. to do with the environment, to do with what you said and to do with the continuing issue of corruption. on the environment, most business people here do not want to be associated with deforestation. pulling talked about brazil out of the paris accord. are you going to go ahead with that? >> the first question on the environment, brazil is a country that more than many protects its reserves and the environment. it is enshrined in law that a farmer must protect 20% to 80% of his farm without state support from the brazilian government. this has to be respected. any change will be made according to the law. for some time, brazil has b

keytruda, from merck. with more fda-approved uses for advanced lung cancer than any other immunotherapy. >>> as the government movers to complete its case against el chapo, there was intriguing testimony this week in a brooklyn courtroom. ont included allega about his wife. >> his escapes are legendary, but it appes a key partner in crime may have helped el chapo pull off one of his daring prison get-aways, his wife. in court this week, a once loyal henchman turned snitch testified the drug lord received an important jailhouse message while planning 2015. scape in >> and the twist here is now we know that the message from prison to his workers and to hiss s came through emma. so she helped build th escape plan. >> reporter: she has declined to comment on the allegations. her husband is facing enmore than a d charges, including drug trafficking, money laundering and conspireing to murder rivals. da security guard testifhat the boss himself interrogated and tortured enemies, even ordering that some be buried

for wall construction with lace or challenges including the question of whether there is an actual merck emergency in the first place. >> in here in the bay area house speaker nancy pelosi with in the area holding a thank you reception for voters. attendees celebrated pelosi's return as the house of house speaker. she had a cake saying happy blue year. pelosi said democrats are in favor of border security, but not a wall. >> we are fighting the president on the wall and that is a fight that we have had. we support border security and we will continue to do suit so. >> policy also trying to tamp down any talk of impeachment for the time being. she said on cbs sunday morning that first the public has to see the results of special counsel robert muller's investigation. >>> gavin newsom takes office as california governor tomorrow. during his campaign some back extended health care, universal preschool and new initiatives to tackle the homeless crisis. some taxpayer groups thing they are concerned about who will put a billboard major spending agenda. >>> and coming up scary moments for men t

keytruda, from merck.h more fda-approved uses for advanced lung cancer than any other immunotherapy. >> welcome back. my next guest is among the pioneers that helped turn private equity into the multitrillion dollar industry it is today. a pioneer on wall street as well. john castle founder, chairman and ceo of castle harlan. over the past 30 as they become a leader among middle-market private equity firms. investing hundred five companies with an enterprise value of over $15 billion. john is also formerly the president and ceo of -- when i hear dlj, my heart warms purities to love that firm and i talked to a lot of your guys back in the day. good to have you on the program. >> is nice to be here, maria. thank you so much for inviting me. >> thank you so much. what is your assessment with what's happening in the market? at the end of the year last year we had real volatility. i think there was a lot of noise out there and what's going on washington, in terms of worries about a growth slow down. what you th

it's facing competition from merck. celgene will lose patent protection for its best selling drug by 2022. celgene shareholder will receive bristol myers squibb stock and cash giving enemy a premiumn the closing price on wednesday. bmo capital marke analysts alex arfay called it expensive butca lo in a letter to investors. >> the rationale is complementary portfolios in cardiovascular decease, a promising pipeline and cos synergiy. >> the merged companies will have products worth $1.0 billion each in annual sales. management says the combined company will create a pipeline of potentially profitable drugs in development with six near-term product launching that could deliver more than $15 billion in revenue potential.xp butts say it all depends on how these drugs come forward d if they get to market. shareholders from both companies and regulators still have t give final approval of the deal. if that happens bristyers squibs acquisition of celgene is expected to be completed by the third quarter of 2019. for "nightly bus

>>>nd fellow dow component merck was downgraded to mart perform from outperform at bemo capital markets. the analyst cited the drug maker's overreliance oner its carug keruda. the price target,$80. >>> and lowe's was downgraded to hold from buy at loop capital the firm is less optimistic about the home improvement retailer's margins right now, so the price target is now $99. nonetheless, the stock rose slightly to $91.83. >>> still ahead, the bright spot in ford's quarterly results. >>> united health care is suing the new amazon, jpmorgan chase berkshire venture. the insurer alleges the group poached an employee and took trade secrets. the suitlaims that the employee now poses a direct threat to united health optum unit. >>> north america was a bright spot for ford of the automaker reported earnings today that missed expectations by 2 cents but that was not exactly a surprise, since the company had already oupreaed those results. revenue, though, was better than expected at more than $38 billion. reaction in initial after-hours trading tonight was mixed. phil lebeau has the one key take

keytruda, from merck.d lung cancer than any other immunotherapy. ♪ [ telephone ringing ] -whoa. [ indistinct talking ] -deductible? -definitely speaking insurance. -additional interest on umbrella policy? -can you translate? -damage minimization of civil commotion. -when insurance needs translating, get answers in plain english at progressiveanswers.com. ♪ -he wants you to sign karen's birthday card. it's a high honor. >> time now for a number of the week. 81. that is the combined age of tom brady and drew brees. both star quarterbacks in this week's championship games. brady is 41, and drew brees is 40. what makes advanced age so striking is that the two face opposition in their bids for a spot in the super bowl this weekend from two of the honest quarterbacks to reach this stage with postseason. brady takes on patrick mahon in the kansas city chiefs, he is 23. while drew brees faces up against jared goff of the los angeles browns.24. brady was as a freshman in college when mahon was born. his mother is b

keytruda, from merck.more fda-approved uses for advanced lung cancer than any other immunotherapy. >>> this is abc 7 mornings. >>> good morning. it is friday. we finally made it. >> we did make it. >> january 25th. >>> we have political news to get to regarding roger stone. first, we're going to talk about weather and traffic. we start with mike. >>> did you like yesterday? >> yes. >> even better today, i think. let's take a look. i'll let you be the judge. i'll report, you decide. sounds like -- never mind. inland in the north bay, towards livermore. 40s elsewhere. the highs today, mid to upper 60s. look at fremont. 69 degrees today. 68 san jose and oakland and santa rosa at 67 in san francisco. i'm tracking more tule fog this morning too. now to sue. >>> coming up on 4:28. the golden gate bridge, two lanes northbound and four lanes southbound. there is or was roadwork. maybe it has been picked up already. they're doing thatri it's mostly this southbound direction coming off the waldo grade. to the san 14

keytruda, from merck.or advanced lung cancer than any other immunotherapy. >> time now for a number of the week. 81. that is the combined age of tom brady and drew brees. both star quarterbacks in this week's championship games. brady is 41, and drew brees is 40. what makes advanced age so striking is that the two face opposition in their bids for a spot in the super bowl this weekend from two of the honest quarterbacks to reach this stage with postseason. brady takes on patrick mahon in the kansas city chiefs, he is 23. while drew brees faces up against jared goff of the los angeles browns.24. brady was as a freshman in college when mahon was born. his mother is brady's age. will age conquer all? or will youth triumph? perhaps a split decision. that is it disrepute next week i will host from the world economic forum in the mountains of switzerland. you will not want to miss the wall street journal at large. thank you for joining us. [♪] lou: good evening. the national security crisis on our southern borde

now with just two months to go until bricks it how merck has become the latest german state to announce plans for its own pricks it bill the legislation would guarantee brits eleven in hamburg the same rights as other e.u. citizens until the end of twenty twenty on one condition that the u.k. leaves the e.u. with a brics it deal. heartbreaks it would mean a shorter transition period of just three months and more complications for brits abroad among them is pub landlord gevo came following in the footsteps of the beatles the liverpudlian first arrived in hamburg in one thousand nine hundred sixty three after putting it off for months he's about to apply for german citizenship i thought it wasn't going to happen i actually really thought it's always like highly paid what you want to they say were politicians it's all people who can get a real job and it's that that's what i that's what i thought give those english purpose been calling in the punters for the past sixteen years but a disorderly bret's it could result in his supplier leaving him without the pints to pull they're going to sto

keytruda, from merck.re fda-approved uses for advanced lung cancer than any other immunotherapy. sometimes a cough gets in the way of a good night's sleep. that's when he needs vicks vaporub. proven cough medicine. with 8 hours of vapors, so he can sleep. vicks vaporub. goodnight coughs. (alarm beeping) welcome to our busy world. where we all want more energy. but with less carbon footprint. that's why, at bp, we're working to make energy that's cleaner and better. we're producing cleaner-burning natural gas. and solar and wind power. and wherever your day takes you... we have advanced fuels for a better commute. and we're developing ultra-fast-charging technology for evs.. at bp, we see possibilities everywhere. so we can all keep advancing. >>> one of the nation's biggest drugstore chains is getting a makeover cvs is revamping its beauty aisle, letting you in on secrets some companies might not want you to know. here's kristen dalgren. >> reporter: ge are the days of a beauty aisle peppered with imes of

keytruda, from merck. more fda-approved uses for advanced lung cancer than any other immunotherapy. >>> finally tonight, one man's amazing grace. >>> finally tonight, one man's amazing grace. spending years in darkness, now at last what he calls the miracle. lately, you'll find charleston, west virginia, resident philip dunn flipping through old photos. he'll tell you he's living in the past, and it's completely fine by him. >> the last clear vision i had of my daughter was her high school graduation. >> reporter: when he was 45 years old, dunn was diagnosed with cataracts and, even worse, macular degeneration. >> the doctor said, you know, it's not that bad. it probably won't give you trouble for years. >> reporter: but dunn says within months he started seeing black dots in the center of his vision that eventually turned into blindness. that was 14 years ago. >> i was really upset. i was thinking about all the things i had lost. and the lord just reminded that i still had a wife. i still had two kids. i

keytruda, from merck. with more fda-approved uses for advanced lung cancer than any other immunotherapy. so i got an offer and now i'm thinking... i'd like to retire early. oh, that's great sarah. let's talk about this when we meet next week. how did edward jones come to manage a trillion dollars in assets under care? jay. sarah. so i have a few thoughts on that early retirement... by focusing our mind on whatever's on yours. >> welcome back. my next guest is among the pioneers that helped turn private equity into the multitrillion dollar industry it is today. a pioneer on wall street as well. john castle founder, chairman and ceo of castle harlan. over the past 30 as they become a leader among middle-market private equity firms. investing hundred five companies with an enterprise value of over $15 billion. john is also formerly the president and ceo of -- when i hear dlj, my heart warms purities to love that firm and i talked to a lot of your guys back in the day. good to have you on the program. >> is ni

keytruda, from merck.da-approved uses for advanced lung cancer than any other immunotherapy. >> republican congressman taylor of north texas was elected for the first time in november. replacing the retired gop representative, johnson. he joins we know from the capital. congressman, thank you indeed for being here. >> great to be on the show, i appreciate you having me. >> thank you. i want to get to the deeper issues that most come into politics.i want to start with an immediate question which is, you are there in washington. the government is still partly shut down. >> sure. >> the impasse seems to go on. how is this going to end? >> let me just say again, thank you for having me, great to be here with you. i served in the state legislature in texas for the last eight years. the contrast could not be greater. the speak of the texas house was elected unanimously. republicans and democrats. they voted on a rules package which was unanimous democrats and republicans come together. i carried 81 bills to let

keytruda, from merck. with more fda-approved uses for advanced lung cancer than any other immunotherapy. i'm off to college. i'm worried about my parents' retirement. don't worry. voya helps them to and through retirement... dealing with today's expenses... while helping plan, invest and protect for the future. so they'll be okay? i think they'll be fine. voya. helping you to and through retirement. >>> next tonight, a shocking warning about the opioid crisis. safety experts grimly noting for the first time ever the odds o dying from an overdose are higher than dying in a car crash. nbc's senior national correspondent kate snow has more in our series "one nation overdose >> reporter: saturday morning, another mass overdose. almost every ambulance in chico, californse, to this same house. >> at one point, we had six cprs in progress. >> reporter: one was he dead, six ot hospitalized on the powerful opioid fentanyl. the odds of dying from an opioid overdose in america at 1 in 96.th at's a higher chance than

keytruda, from merck.h more fda-approved uses for advanced lung cancer than any other immunotherapy. -morning. -morning. -what do we got? -keeanyen ranch. mighgewiy.ng. have a good shift. fire pit. last use -- 0600. i'd stay close. morning. ♪ get ready to switch. protected by flo. should say, "protected by alan and jamie." -right? -should it? when you bundle home and auto... run, alan! ...you get more than just savings. you get 'round-the-clock protection. >>> to the "index" of other news tonight. and an urgent manhunt for a suspect in four georgia murders. authorities say 27-year-old daylon gamble is armed and dangerous and on the run after two separate double homicides overnight northwest of atlanta. a fifth shooting victim survived. authorities believe the victims all were targeted. >>> there was a deadly midair collision in the italian alps. a small plane filled with tourists colliding with a helicopter carrying skiers and crashing onto a glacier at 10,000 feet. five people are dead. one survived but w

now with just two months to go until bricks it how merck has become the latest german state to announce plans for its own pricks it bill the legislation would guarantee brits a living in hamburg the same rights as other e.u. citizens until the end of twenty twenty on one condition that the u.k. leaves the e.u. with a brics it deal. heartbreaks it would mean a shorter transition period of just three months and more complications for the brits abroad among them is pope landlords give ok i'm following in the footsteps of the beatles the liverpudlian first arrived in hamburg in one thousand nine hundred sixty three after putting it off for months he's about to apply for german citizenship i thought it wasn't going to happen i actually really thought it's always like highly paid what you want to the politicians it's all people who can get a real job and it's that that's what i that's what i thought get those english class has been calling in the punters for the past sixteen years but a disorderly breck's it could result in his supplier leaving him without the pints to pull the stockpile in a

keytruda, from merck.h more fda-approved uses for advanced lung cancer than any other immunotherapy. welcome to monowi, nebraska, population one. me. i'm mayor, secretary, treasurer. every decision you have to make yourself. four out of five women will become solely responsible for their finances. i like the independence and every woman should have that, you know? i make my decisions, and if they're wrong, i live with them. if they're right, then i'm very proud of myself. plan your financial life with prudential. bring your challenges. >> glor: the streets of los angeles today were filled with striking teachers. tony dokoupil has more on why reachers walked out in the nation's second largest ecstrict. >> u.t.! >> l.a.! >> reporter: los angeles teachers hit the streets today by the tens of thousands, offering a lesson in civic engagement. >> whose schools? >> our schools! >> reporter: they're protesting budget cuts that affect some 600,000 l.a. students, more than 80% of them low income. anna aderonmu teach

keytruda, from merck.ith more fda-approved uses for advanced lung cancer than any other immunotherapy. >> ninan: this has been a busy day for pope francis as he continues his visit to panama for world youth day. seth doane has more. >> reporter: in a brand newly renovated basilica in panama city, pope francis directed his comments today to clergy and spoke of weariness which can come from seeing a church wounded by sin. rgt the pontiff urged priests td nuns to find energy from their faith, despite the challenges. that's what world youth day is designed to do: engage hundreds of thousands of catholics who have made the pilgrimage here. >> it makes you feel calm, like-- >> reporter: to see the pope? >> yes. >> reporter: the atmosphere often resembles a concert, more than a religious event. be it's, like, really happy, and you just want to, like, jump up and down. but then that would be habarrassing. >> reporter: we met zach adkins, who had come from connecticut to join the throngs to at least see the pope. >

keytruda, from merck. with more fda-approved uses for advanced lung cancer than any other immunotherapy. >>> we turn next tonight to the sink hole revealing a secret tunnel, headed for a bank in florida. here's abc's victor oquendo. >> reporter: tonight, an elaborate bank heist thwarted. >> reptepoliceamnitely from ig . sink hole in florida, they spotted a power cord inside. this chase bank. >> i would say it's attempted burglary of a bank. they were headed towards the atm. i don't think they were doing that for any other reason. >> reporter: the fbi and local authorities using a robot and k-9 units to sweep the narrow tunnel, which stretches about 50 yards, just two to four feet wide. inside, boots, a ladder, a wagon, digging tools and a small generator. investigators think it took more than one person to build this tunnel, and tonight, they're asking the public to help find them. >> we don't know who's behind this at this time. they could've been here a week ago, last night. we don't know at this time. >