the mhra, and the briefing involving the mhra is due here at three o'clock this afternoon. is going to give its assessment later on this afternoon of the astrazeneca vaccine. anna holligan has more from the ema's headquarters in amsterdam. so we are expecting updates from the ema's team that specialises in adverse reactions. these vaccines are seen as the way out of the pandemic, but only if people have enough confidence and faith to actually take them. so, you will remember last month the ema issued guidance which said the benefits of taking the oxford astrazeneca jab outweighed the potential risk of side—effects. they also said any causal link between these extremely rare blood clots and the vaccine were possible but not proven, and the evidence suggested that people should continue to take it. we've seen governments across the eu adopting different approaches though — some, including here in the netherlands and across the border in germany, have paused the use of the astrazeneca jab among the under—60s. in france, it's the under—55s. so what we are expecting from the ema

what is the mhra saying? that the first thin it what is the mhra saying?_ what is the mhra saying? that the first thing it is important _ what is the mhra saying? that the first thing it is important to - what is the mhra saying? that the first thing it is important to say - first thing it is important to say is that a link between these rare clots in the brain and astrazeneca dab isn't proven, but the uk regulator is investigating. these clots do occur naturally. they are quite rare. the first thing you need to unpick is, is this just a coincidence or is it a very rare side—effect of the astrazeneca jab? and the incidence is low, 30 cases reported to the uk medical regulators out of 18 million jabs. that is one event in about every 600,000 astrazeneca jab is. pfizer, on the other hand, hasn't had any clots linked to it that the uk authority says. these clots have caused some european countries to restrict who they are giving the vaccines to. germany isn't giving the astrazeneca jab to anyone under the astrazeneca jab to anyone under the age of 60, but the

i think the mhra has got access to very good expert advice.d, that there were no events arising in this trial to cause the trial to be paused. but since we are expecting the mhra, and, i think also the ema, to come up and, i think also the ema, to come up with another review of the data, it is extremely cautious and prudent to pause a trial recruitment until we have that opinion. it is important to note that the ema and the mhra and the world health organization have been consistent in the view, up until now, that the benefits of this vaccine far outweigh the risks. benefits of this vaccine far outweirh the risks. �* . . outweigh the risks. bearing that in mind, dr outweigh the risks. bearing that in mind. dr maggie _ outweigh the risks. bearing that in mind, dr maggie wearmouth - outweigh the risks. bearing that in mind, dr maggie wearmouth from i outweigh the risks. bearing that in - mind, dr maggie wearmouth from the joint committee on vaccination and immunisation has said that it might be better to halt the roll—out for younger people unti

the mhra said last week there had been 30 rare cases of blood clots including seven deaths.me minister, visiting an astrazeneca plant in macclesfield, once again gave his firm support for the vaccine. the best thing people should do is look at what the mhra say, our independent regulator, that's why we have them, that's why they're independent. and their advice to people is to, you know, keep going out there, get yourjab, get your second jab. as a precautionary measure, the mhra updated its advice last month to say that anyone with a headache that lasted for more than four days after receiving the astrazeneca vaccine or bruising beyond the site of the jab should seek medical attention. both of the vaccines we're using are highly effective against covid, and the risks of getting sick or dying of covid, for all the people currently being offered first and second doses, are far and away greater than any small theoretical risk that may exist relating to these cases, which are extremely rare. as for the future course of the epidemic here, three academic groups modelling the outbr

the best thing people should do is look at what the mhra say, our independent regulator.e them, that's why they're independent. and their advice to people is to, you know, keep going out there, get yourjab, get your second jab. as a precautionary measure, the mhra updated its advice last month to say that anyone with a headache that lasted for more than four days after receiving the astrazeneca vaccine or bruising beyond the site of the jab should seek medical attention. both of the vaccines we're using are highly effective against covid, and the risks of getting sick or dying of covid, for all the people currently being offered first and second doses, are far and away greater than any small theoretical risk that may exist relating to these cases, which are extremely rare. as for the future course of the epidemic here, three academic groups modelling the outbreak all have multiple scenarios showing a third covid wave after a final lifting of restrictions in england in latejune. this model from warwick university looks at the number of patients in hospital with covid, whic

hours mhra the — information within the next 24 hours mhra. for your time. thank you for answering some of those questions. 7:20am _ answering some of those questions. 7:20am now— answering some of those questions. 7:20am now and at 8:30am we will speak— 7:20am now and at 8:30am we will speak to _ 7:20am now and at 8:30am we will speak to fergus walsh. if you have questions. — speak to fergus walsh. if you have questions, and i'm sure there are lots, _ questions, and i'm sure there are tots, we — questions, and i'm sure there are tots, we will _ questions, and i'm sure there are lots, we will speak to him he can go through— lots, we will speak to him he can go through some of those with us. we have through some of those with us. have more through some of those with us. - have more academics with us just after 8am. professor callum semple, professor of child health and medicine at the university of liverpool and also the professor of medicine at the university of east anglia will both be here at 8:10am. plaid cymru is launching its manifesto to

i think the mhra plan _ before the roll-out? i think the mhra plan on _ before the roll-out?itor the safety effects. and i think the yellow card scheme has been heavily pushed towards members of the public. to make sure they understand that they need to report any side effects. and that has also given us information to people attending vaccination for example. i think there is possibly a lack of general public understanding of the way that we regulated drugs and manage drug advice and safety. it is more of an educational problem that we could perhaps bring into schools and things so people understand that real events like these can only be found when a vaccine or a drug hit the broader population. i think the british public have been very sensible in how they have dealt with lockdown restrictions. even this blood to clot issue over the past month, vaccine hesitancy doesn't seem to be affected by the debate thatis seem to be affected by the debate that is happening. so i would have thought having transparent meetings with clear decisive decisions being made about who should or

the official regulator, the mhra, said the guidance was not proof the vaccine had caused the clots, butid the link was getting firmer. so, from now on, people aged between 18 and 29 will be offered an alternative to the oxford—astrazeneca jab. but those who've already had a first dose of the astrazeneca vaccine should go ahead and get the second. pregnant women and people with certain blood disorders should consult a doctorfor advice. and the medical regulator has insisted that the benefits of taking the astrazeneca vaccine still far outweigh the risks for the vast majority of people. 0ur medical editor, fergus walsh, looks at the factors behind today's changes. turn up, get yourjab. the message remains the same. but in future, for the first time, the covid vaccine you receive will depend on your age. that's because evidence is emerging of a link between the oxford—astrazeneca vaccine and very rare blood clots. the uk regulator, the mhra, said up to the end of march there have been 79 cases of rare clots with low platelets following a first dose of the astrazeneca vaccine. 19 people hav

thank you. | i will now update on mhra's rigorous scientific— i will now update on mhra's rigorous scientificbeen given in the uk, and we know— have been given in the uk, and we know that — have been given in the uk, and we know that vaccines are the best way to protect _ know that vaccines are the best way to protect people from covid—19 and have already saved thousands of lives _ have already saved thousands of lives and — have already saved thousands of lives and in fact, around 6000, modelled — lives and in fact, around 6000, modelled in the uk, by the end of february — modelled in the uk, by the end of february. but no effective medicine or vaccine _ february. but no effective medicine or vaccine is— february. but no effective medicine or vaccine is without risk. with vaccines, — or vaccine is without risk. with vaccines, more complex than usual, because _ vaccines, more complex than usual, because the — vaccines, more complex than usual, because the benefits can be to people — because the benefits can be to people other than the individual taking _ people other than the individual takin

ttj: best thing people should do is look at what the mhra say, our independent regulator, that is why that is why they are there, they are independent, their advice is to keep going out there and get yourjab, get your second keep going out there and get yourjab, get yoursecond jab your jab, get your second jab upright yourjab, get yoursecond jab upright as a precautionary measure, the mhra updated its advice last month to say that anyone with a headache that lasted more than four days after receiving the astrazeneca vaccine or bruising beyond the sight of the jab should seek medical attention. sight of the jab should seek medicalattention. both sight of the jab should seek medical attention. both of the vaccines we are using a highly effective against covid and the risks of getting sick of dying of covid are all the people being offered first and second doses are far greater than any theoretical risk related to these cases which are rare. this could be compromised if people — this could be compromised if people think this is not being taken seriously and examined the great detail but

the mhra said last week, there had been 30 rare cases of blood clots, including seven deaths.neca plant in macclesfield, once again gave his firm support for the vaccine. the best thing people should do is look at what the mhra say, our independent regulator, that's why we have them, that's why they're independent. and their advice to people is to, you know, keep going out there, get yourjab, get your second jab. as a precautionary measure, the mhra updated its advice last month to say that anyone with a headache that lasted for more than four days after receiving the astrazeneca vaccine or bruising beyond the site of the jab should seek medical attention. both of the vaccines we're using are highly effective against covid, and the risks of getting sick or dying of covid, for all the people currently being offered first and second doses, are far and away greater than any small theoretical risk that may exist relating to these cases, which are extremely rare. as for the future course of the epidemic here, three academic groups modelling the outbreak all have multiple scenarios

we had two press - conferences yesterday, one from mhra, _ conferences yesterday, one from mhra, jcviere are other reasons - more likely to develop the clots. there are other reasons womeni more likely to develop the clots. i there are other reasons women are more _ there are other reasons women are more tikety— there are other reasons women are more likely to — there are other reasons women are more likely to develop _ there are other reasons women are more likely to develop them - more likely to develop them generally— more likely to develop them generatty but _ more likely to develop them generally but in— more likely to develop them generally but in this - more likely to develop them i generally but in this instance. more likely to develop them - generally but in this instance. the decisions — generally but in this instance. the decisions are _ generally but in this instance. the decisions are being _ generally but in this instance. the decisions are being made - generally but in this instance. the decisions are being made for- generally but in this instance. the decisions are bei

the best thing people should do is look at what the mhra say, our independent regulator.s why we have them, that's why — they're independent. the risks of getting sick or dying of covid for all the people currently being offered first and second doses, are far and away greater than any small, theoretical risk that may exist relating to these cases, which are extremely rare. we'll be looking at why scientists think we may still get a third wave of infections. also tonight: the argument over so—called covid passports — you may need it to travel abroad — but you will definitely not need it for essential services. the disappearance of 19—year—old richard okorogheye — the met police say they are still trying to identify a body. the crowd should disperse immediately. _ in northern ireland, the stormont assembly's recalled after several nights of violence. the sky at night — with less light pollution during the lockdown, we've had some spectacular views. and and coming up on the bbc news channel. an audition for europe's most wanted as borussia dortmund's erling haaland prepares

the medicines regulator, the mhra, said the evidence had been "firming up" that a link exists betweens working with officials to try to understand what is causing these "extremely rare events". alison astles' brother neil died on sunday from a blood clot on the brain. he had been given the astrazeneca vaccine. he was 59. she urged other people to continue to have the jab and said her brother had been "extraordinarily unlucky". she's been speaking to my colleague annita mcveigh. he had a vaccine on the 17th and probably about a week or so later, he started getting headaches which didn't go away and he started feeling sick as well, which again didn't go away. after about eight days of this, he got to the stage where he was starting to lose his vision and my other brother took him to a&e on friday night, and a scan there revealed a huge blood clot and bleed in his brain, so he was transferred over to icu where, unfortunately, he died on sunday evening. i am so, so sorry. what have you been told about any possible link between the vaccination and his death? the coroner is still preparing

speaking in the last hour, the chief executive of the mhra june raine gave more details about those whoen affected by the rare blood clots. based on the current evidence, the benefits of the covid—19 vaccine astrazeneca against covid—19 and its associated risks, hospitalisation and death, continues to outweigh the risks for the vast majority of people. our review has reinforced that the risk of this rare suspected side effect remains extremely small. by 31 march, over 20 million doses having been given, we have had 79 case reports, up to including that date, 31 march. all 79 cases occurred after the first dose. of these 79 cases, 19 people have sadly died. these cases occurred in 51 women and 28 men, aged from 18 to 79 years. and from these reports, the risk of this type of rare blood clot is about four people in a million who receive the vaccine. three out of the 19 were under 30 years. 1a of the 19 were of the cerebral venous sinus thrombosis with low platelets, and five or other kinds of thrombosis in major veins. the balance of benefits and risks is very favourable for older people,

two more vaccines are being assessed by the regulator, the mhra. janssen, 30 million doses. trials are ongoing with other vaccines where the government has made preliminary orders. so will confidence in the oxford—astrazeneca vaccine be affected? people in younger age groups we spoke to had varying opinions. i am a bit concerned to hear it because i'm 2a and i've already had my first dose of the astrazeneca vaccine. and i have my second dose booked in for a couple of weeks. it's one of those very rare cases. but it might happen, but it probably won't. the risk is probably, it's probably worth the risk, right? i'm still all for it. i'm going to do a little bit more research now into it, _ but i still think at this point - i would get the astrazeneca vaccine. officials say the benefits outweigh the risks for the vast majority of adults. it remains to be seen how people react. hugh pym, bbc news. 0ur political correspondent damian grammaticas is in westminsterfor us. we have just heard we havejust heard boris we have just heard borisjohnson speaking.

two more vaccines are being assessed by the regulator, the mhra.ses on order, and janssen, 30 million doses. trials are ongoing with other vaccines where the government has made preliminary orders. so will confidence in the oxford—astrazeneca vaccine be affected? people in younger age groups we spoke to had varying opinions. i am a bit concerned to hear it because i'm 2a and i've already had my first dose of the astrazeneca vaccine. and i have my second dose booked in for a couple of weeks. it's one of those very rare cases. it might happen, but it probably won't. the risk is probably, it's probably worth the risk, right? i'm still all for it. i'm going to do a little bit more research now into it, _ but i still think at this point - i would get the astrazeneca vaccine. officials say the benefits outweigh the risks for the vast majority of adults. it remains to be seen how people react. hugh pym, bbc news. we will be answering more of your questions at 8:30pm right here on bbc news right here about the oxford/astrazeneca vaccine, so send any questi

look at what the mhra say, our independent regulator.t's why we have them, that's why they are independent, and their advice to people is to keep going out there and get yourjab, get your second jab. for the time being, forthe time being, there is no evidence — forthe time being, there is no evidence that the benefit risk assessment for the vaccine needs to be changed. police searching for missing student richard okorogheye say a body has been found in a pond in epping forest. the met says the man has yet to be formally identified, but a post—mortum will take place. the president's son speaks out. hunter biden — targeted by donald trump for his drug addiction and financial deals, gives the bbc his version of a troubled past. i created a perception and a perception that was wielded against us in an incredibly wild and conspiratorial way. and the biden name is synonymous with democracy and transparency, and that is why i said that it was gold to them. and star light star bright — why the pandemic means less light pollution and a better cha

two more vaccines are being assessed by the regulator the mhra — novavax, where there are 60 millionder, and janssen, 30 million doses. trials are ongoing with other vaccines where the government has made preliminary orders. so will confidence in the oxford—az vaccine be affected? people in younger age groups we spoke to had varying opinions. i am a bit concerned to hear it, because i'm 2a and i've already had my first dose of the astrazeneca vaccine, and i have my second dose booked in for a couple of weeks. it's one of those very rare cases. but it might happen, but it probably won't. the risk is probably... it's probably worth the risk, right? i'm still all for it. i'm going to do a little bitl more research now into it, but i still think at- this point i would get the astrazeneca vaccine. it remains to be seen how people react to today's announcement, so one leading official made the point that the chance of getting a blood clot to having covid—19 was much higher than with the az vaccine. hugh pym, bbc news. now on bbc news — our world. hadicha is fighting forjustice. her husband

the mhra said a review was ongoing but that no link to the vaccine had been proven.es when invited to do so, because the benefits outweigh any risks. 0ur science correspondent rebecca morelle is here with me. how should people interpret these findings? well, it is really important to emphasise that no link between these rare blood clots in the astrazeneca vaccine has been proven, but the uk regulator is investigating this, and these blood clots are really unusual. they are accompanied by low levels of platelets, these are a type of blood sell that at low levels normally cause bleeding, not blood clots, and they are serious, so the mhra has had 30 cases reported, and we will end this evening that of these, seven people have sadly died, and i have been deaths reported in europe too. the incidence is low, out of 18 million vaccinations of the astrazeneca jab given, and the regulator also said that defies a jab, they've seen two cases of brain blood clots. —— the pfizerjab. but these are without the unusual low platelet counts. the thing we need to unpick is whether thes

last week, the mhra said there had been 30 rare cases of blood clots, including seven deaths after 18ine. and its benefits far outweighed any risks. both of the vaccines we're using are highly effective against covid, and the risks of getting sick or dying of covid, for all the people currently being offered first and second doses, are far and away greater than any small theoretical risk that may exist relating to these cases, which are extremely rare. despite a fall in supply, the government says the uk remains on track to offer all adults a first dose of one of the three approved covid vaccines by the end ofjuly. our health correspondent, anna collinson is here. more generally can you put these numbers about blood this evening is been confirmed the trial has stopped immunising. while the uk regulator investigates these rare type of blood clots that may be linked with the ashes jab. mane rare type of blood clots that may be linked with the ashes jab.— linked with the ashes “ab. none of the children h linked with the ashes “ab. none of the children involved _ linked with the ashes jab

the uk regulator, the mhra, said up to the end of march, there have been 79 cases of rare clots withlets following a first dose of the astrazeneca vaccine. 19 people have died. that's out of 20 million who received the jab. that's one rare clot in every 250,000 vaccinations. these monitoring systems are now detecting a potential side effect of the covid—19 vaccine astrazeneca in an extremely small number of people. the evidence is firming up. the balance of benefits and known risks of the vaccine is still very favourable for the vast majority of people. very few adults under 30 have died from covid, so that changes the risk—benefit balance from getting a vaccine. it's thought younger adults are at higher risk from clots after the astrazeneca jab, about one in every 100,000 doses. so they will be offered a different vaccine when their time comes. are you worried that this change of course might damage these are really carefully considered decisions, and it remains vitally important that people who are called back for their second dose come for it, and it remains vitally important that

the mhra said a review was ongoing, but that no link to the vaccine had been proven.their vaccines when invited to do so because the benefits outweigh any risks. our science correspondent rebecca morelle explains more. these clots are unusual in that they're associated with low platelet levels, and platelets are a type of blood cell that normally cause bleeding, not clotting, and these clots can affect the brain, too. so, what needs to be unpicked is whether these are happening naturally or whether they're a really rare reaction to the astrazeneca jab. the incidence is low, so 30 cases out of 18 million jobs. so that's about one event in every 600,000 astrazeneca vaccines. and the uk regulator said there have been two cases of brain blood clots with the pfizer vaccine, too, but these don't have the low platelet counts associated with them, so they're slightly different. but these clots have caused some countries to actually restrict who they give the vaccine to. so, today, the netherlands has announced that it's not going to be giving the astrazeneca jab to people und

i think what the mhra, the government and dj cvi is exactly correct... what the mhra, the governments exactly correct... finally, do ou cvi is exactly correct... finally, do you believe _ cvi is exactly correct... finally, do you believe that _ cvi is exactly correct... finally, do you believe that there - cvi is exactly correct... finally, | do you believe that there should cvi is exactly correct... finally, - do you believe that there should be some kind of analysis now as to whether or not it is possible to use two different facts and needs bearing in mind that there are no concerns over, very minor concerns it has to be said, because of the rarity of blood clots but do you believe now that should be studies looking into possibly combining two vaccines? my looking into possibly combining two vaccines? g , ., , vaccines? my understanding is studies are — vaccines? my understanding is studies are ongoing _ vaccines? my understanding is studies are ongoing all - vaccines? my understanding is studies are ongoing all the - vaccines? my understanding is. studies are ongoing all the time

its sale in the uk is now being investigated by our medicines regulator, the mhra. doctors say this using the syrup can cause fatigue, jaundice, and even liver failure. these women say they've experienced other problems too. i was probably overdosing myself. i collapsed in the street and they brought me into hospital. i couldn't even write my name on a piece of paper. my hands were shaking that much. it even hurt my eyes to be awake. i was told taking the apetamin would only make me gain weight round my bum and my hips and my thighs. and to be honest with you, it's quite daft of me to think that. one influencer in the us claims apetamin caused her to pass which led to this... as the unlicensed medicine's popularity on social media grows, so does concern. what particularly worries me about apetamin is the way it is marketed. it is marketed as a vitamin supplement, which implies that it is safe, that it is natural. you know, although on the bottle it very nicely tells you how much of each ingredient is in there, there's no regulating body that is actually ensuring tha

the uk regulator, the mhra, said up to the end of march, there have been 79 cases of rare clots withlowing a first dose of the astrazeneca vaccine. 19 people have died. that's out of 20 million who received the jab. that's one rare clot in every 250,000 vaccinations. these monitoring systems are now detecting a potential side effect of the covid—i9 vaccine astrazeneca in an extremely small number of people. the evidence is firming up. the balance of benefits and known risks of the vaccine is still very favourable for the vast majority of people. very few adults under 30 have died from covid, so that changes the risk—benefit balance from getting a vaccine. it's thought younger adults are at higher risk from clots after the astrazeneca jab, about one in every 100,000 doses. so, they will be offered a different vaccine when their time comes. are you worried that this change of course might damage vaccine confidence, especially in the young? these are really carefully considered decisions, and it remains vitally important that people who are called back for their second dose come for it,

it is also to talk to the european and british regulators, the mhra and the ema, because it might be the adenovirus vector vaccines, the astrazeneca oxford, thejohnson & johnson and astrazeneca oxford, thejohnson &johnson and the russian vaccines. a few days to get their heads around it is warranted. ten years ago this would not be a big deal, but now we have a new world with a very aggressive anti—vaccine landscapes and that makes it more complicated and problematic.— more complicated and problematic. more complicated and roblematic. , . ., problematic. yes, we will come back to that _ problematic. yes, we will come back to that in _ problematic. yes, we will come back to that in the _ problematic. yes, we will come back to that in the second. - problematic. yes, we will come back to that in the second. it i back to that in the second. it sounds as though you expect the numbers to go up? i sounds as though you expect the numbers to go up?— numbers to go up? i think it's a possibility- _ numbers to go up? i think it's a possibility. remember- numbers to go up? i think it's a possibil

and i think it is also to talk to the european and british regulators, the mhra and the ema, becauserare pathway for the adenovirus vector vaccines, astrazeneca oxford, johnson &johnson and oxford, johnson & johnson and maybe oxford, johnson &johnson and maybe even the russian vaccine. a few days to get around it is warranted. years ago this would not be such a big deal, but we now have a new world with a very aggressive anti—vaccine landscape and that makes it more complicated and problematic.— more complicated and problematic. more complicated and roblematic. , . ., problematic. yes, we will come to that in _ problematic. yes, we will come to that in a _ problematic. yes, we will come to that in a second. _ problematic. yes, we will come to that in a second. it _ problematic. yes, we will come to that in a second. it sounds . to that in a second. it sounds as if you expect the numbers to go up. i as if you expect the numbers to no u. ~' as if you expect the numbers to .o u, ~' �* , ., go up. i think it's a possibility. - go up. i think it's a - possibility. remember, we go up. i th

the medicines regulator, the mhra, is reviewing 30 cases of clots out of more than 18 million vaccinationselle has more. the astrazeneca jab has been rolled out across the uk, providing vital protection against covid—19. no link between rare blood clots and the jab has been proven, but the uk medical regulator is investigating. the clots are unusual. they're accompanied by low levels of platelets, which are a type of blood cell. 30 cases have been reported and seven deaths. this is out of 18 million doses, so the incidence is extremely low. now scientists are trying to establish whether the clots have occurred naturally or are very rare reactions to the astrazeneca jab. because something has been reported, does that mean that it's a side effect? well, if we look at all the side—effects that have been reported, or possible side effects that have been reported, they include excess wind, alcohol poisoning, getting pregnant. there are so many things people report because they happen shortly after people have the vaccine — within a few weeks of them having the vaccine. that does not mean that t

its sale in the uk is now being investigated by our medicines regulator, the mhra.oblems too. i was probably overdosing myself. i collapsed in the street and they brought me into hospital. i couldn't even write my name on a piece of paper. my hands were shaking that much. it even hurt my eyes to be awake. i was told taking the apetamin would only make me gain weight round my bum and my hips and my thighs. and to be honest with you, it's quite daft of me to think that. one influencer in the us claims apetamin caused her to pass which led to this... as the unlicensed medicine's popularity on social media grows, so does concern.

this also received approval a while ago by the mhra. uk has l a while ago by the mhra.e are currently using. it will be an important tool. we have - we are currently using. it will be i an important tool. we have already started _ an important tool. we have already started in _ an important tool. we have already started in scotland, _ an important tool. we have already started in scotland, doses - an important tool. we have alreadyj started in scotland, doses moderna given— started in scotland, doses moderna given vesterdav _ started in scotland, doses moderna given yesterday in _ started in scotland, doses moderna given yesterday in wales _ started in scotland, doses moderna given yesterday in wales and - started in scotland, doses moderna given yesterday in wales and stay l given yesterday in wales and stay from _ given yesterday in wales and stay from england _ given yesterday in wales and stay from england. as _ given yesterday in wales and stay from england. as we _ given yesterday in wales and stay from england. as we have - given yesterday in wales and stay i fro

the mhra, _ vaccine? you cut out. i hope you can still hear me. the mhra, the - vaccine?ford vaccine, and these are rare incidents. the vaccination programme according to public health england has saved something like 6300 lives in the over 705, so it is important the regulator continues to look at these rare instances, and they are, and we will follow their advice on the advice at the moment is if you get the call, take the jab. i is if you get the call, take the 'ab. ~ . is if you get the call, take the 'ab. ~' ., , ., is if you get the call, take the 'ab. ~' ., i. . ,, ,., is if you get the call, take the 'ab. «i ., i. . «i ,., jab. i think we have you back so we have established _ jab. i think we have you back so we have established full _ jab. i think we have you back so we have established full access - jab. i think we have you back so we have established full access to - jab. i think we have you back so we| have established full access to you, we can see and hear you. you did... i wonder if regulators are looking at the risk of young people getting the vaccine. the

approval— vaccine we would wait for mhra approval and take guidance from then and the _ approval andrately and safely. the priority right now is to -et safely. the priority right now is to get your— safely. the priority right now is to get your vaccine if you're offered it, get your vaccine if you're offered it. because — get your vaccine if you're offered it, because we have the supply to vaccinate — it, because we have the supply to vaccinate you if you are eligible. and on— vaccinate you if you are eligible. and on fan— vaccinate you if you are eligible. and on fan ownership in the german approach to this, jessica, i think thatis approach to this, jessica, i think that is a matter for tracey crouch and her review. i wouldn't want to pre—empt what she is going to say. but i know that she is very interested in those sorts of models and what that may or may not involve. huffington post. prime minister, involve. huffington post. prime minister. you — involve. huffington post. prime minister, you have _ involve. huffington post. prime minister, you have set - involve. huffington post.

the mhra says the benefits of vaccines continue to outweigh any risks.country to announce a pause in astrazeneca injections for the under—60s. 0ur science correspondent rebecca morelle told me that while the uk regulator is investigating, a link between the rare blood clots and the vaccine hasn't been proven. these clots are unusual in that they're associated with low platelet levels, which are a type of blood cell that normally causes bleeding, not plotting. and they can affect the brain too. whether these are happening naturally, whether they're happening naturally, whether they�* re a happening naturally, whether they're a really rare reaction to the astrazeneca jab. the incident is low, so 30 cases out of 80 million jabs. 0ne low, so 30 cases out of 80 million jabs. one in every 6000 hundred vaccine. the uk regulators have been two cases of brain blood clots with the pfizer vaccine, but these don't have the low platelet counts associated with them, so they're slightly different. but these clots have caused some countries to actually restrict who they

this is the job of the mhra, the job of the e.m.a. they have to do this.no question about this. annmarie: completely. it shows there is transparency, especially when you have things like a lot of vaccine hesitancy in the united states. sam, you mentioned in your research that it doesn't exactly matter for the u.s. vaccine program, but who is really going to be in trouble if this johnson & johnson does not get the green light quickly? >> i think you could create a spectrum, if you like, of the world, europe, the european union, u.k. and then the united states. the united states has -- and let's not forget this has been partly luck. most people for the amount of vaccines want work. we were all hoping for the traditional vaccines to work. but it turned out to be the other way around. they have all worked, but there is a side effect issue. they have enough to vaccinate the majority of its population. european union, coverage, don't have a problem. the problem is the rest of the world. not only are these vaccines from j and j and astrazeneca easier to distribut

the mhra _ categories. could you answer one question? the mhra reported i categories.usal link established. we have to be careful about drawing any conclusions from that. any incident will be looked at carefully but it is premature for anyone to try to draw any causal link or conclusions from that. it's right when they say this vaccine is safe, and the benefits of taking this vaccine more than outweigh any potential possible impacts. than outweigh any potential possible im acts. ., ~ than outweigh any potential possible im-acts. ., ,, i. than outweigh any potential possible im-acts. ., ,, ., than outweigh any potential possible imacts. ., ~' ., impacts. thank you for your time this morning- _ let's catch up on a busy easter weekend of sport. and it isn't over, fixtures today as well but you are looking back at last night? yes, what happens when your team is 1-0 yes, what happens when your team is 1—0 down at half—time? a good old talking to from the manager, that is what happened to the team at old trafford. manchester united manager ole gunnar solskjaer said he had to