he was very much interested in what we call monoa miy, since he was interested in what caused drug induced parkinson from reserpin, a drug from india, it caused people in animals to become parkinsonian no one knew how that work. but early investigators found a decrease in serotonin. he was interested. i wonder if it decreases dope minute. he gave to animal and showed a decrease as well as serotonin. then he said which one is it. so he took rabbits. he injected reserpin, made the rabbits listless, droop, couldn't move, their ears dropped down and then injected the precursor for serotonin, nothing happened. injected the precursor for dopamine which is l-dopa and the animals woke up. carlson recognized, this is very important, and he came up with a hypothesis that dopamine is somehow involved in parkinson's disease. he came up with this hypothesis in 1959 and eventually he won the nobel prize the same year that eric won it. >> okay. anne young tell me about huntington's. >> huntington's is a little different that parkinson's but it starts insidiously just like parkinson's. it begins in midlif