it's not just about infections that you think of like museumia and urinary tract infections, it's about modern medical care. treatment. arthritis, organ transplants, dialysis, chemotherapy. 600,000 americans get chemotherapy a year. in all of those situations, we expect there to be severe infections because we're suppressing the immune system. we expect to be able to treat them. if we can't treat them, we risk undermining much of modern medicine. we've estimated based on careful analysis of data that between one-third and one-half of all of the antibiotics used in this country with either completely unnecessary or too brad. it could be narrower spectrum. we need to do some things in terms of getting better tools for diagnosis. it would be easier if you could quickly tell, oh, is it a bacteria or virus, a resistant bacteria or not, we don't have that yet. we can do a lot more to be better stewards of the antibiotics we have. we need new antibiotics. we haven't had new antibiotics recently. but we're not going to invent our way out of this. the microbes outnumber us. we have to outsmart t