nad and vitamin b3, as you said, have always been important for normal health and growth.couple of families who had had multiple miscarriages and babies who had had multiple birth defects. they had heart defects, kidney defects. some of them had clu bfoot, defects, kidney defects. some of them had clubfoot, some of them had a cleft palates as well. we were sequencing the genes in these families and we found mutations in specific genes which that last of these discoveries. they basically pointed the way and said, you'd better look at the nad levels in these families based on the genetic mutations. that is what we did. we found the levels were low and we moved into a preclinical experimental model where we were able to prevent those miscarriages and earth defects by adding niacin and earth defects by adding niacin and increasing niacin in the drinking water, and we were able to prevent miscarriages and birth defects completely. professor, many thanks indeed. still to come: bizarre scenes at the world championships as the botswana star sprinter goes solo for the 200m. the big

and really, it is starting pretty nice nad bright across most areas. there, but on balance, fine start from the south—east, the midlands, wales. a couple of showers there around the lake district, maybe a few dotted around in northern ireland and western scotland, but on the whole, a nice start to the day. and here is that overnight rain moving away towards the north—east, off the edge of the screen — good riddance. now, as far as tuesday morning, and the second half of the morning and the afternoon is concerned, showers are actually going to be brewing inland. so it is not a completely dry day. take a brolly if you are out for any lengthy period of time. sunny spells — plenty of them, yes, and feeling quite warm, but there will be showers breaking out. how are we doing compared to the rest of europe? well, london will be warming up to 24 degrees. we're on a par with paris, but some storms around here, similar to warsaw and moscow. but hotting up across spain and portugal, and in italy and rome, there, temperatures up to around 35 degrees celsius. anyw

the majority of the region either nad heat advisory in the color orange or an excessive heat warning. we'll get a much closer look at how hot we'll get and how long the heat will last coming up in a few minutes. >> it has now been nearly 24 hours since hurricane harvey hit the texas coast. a look at the damage and the problems ahead. >>> and introducing an icon to a new generation. a group of bay area girls >>> in texas today harvey has been down graded from a category 4 hurricane to a tropical storm but the damage has been done. drone footage shows the damage that has been done in rockport, texas. here's reporter. >> reporter: more than 22 inches of rain is forecasts to flood parts of texas as hanchy weakens in strength but in no hurry to move on as it stalls over the loan star state. houston remains a huge concern after that city typically floods after two or three inches of rain. 130 mile-per-hour winds uprooted trees, tore houses apart and collapsed entire buildings, leaving streets littered with debris. wide-spread devastation is being reported by rockport. who said to write thei

the majority of the region either nad heat advisory in the color orange or an excessive heat warning. we'll get a much closer look at how hot we'll get and how long the heat will last coming up in a few minutes. >> it has now been nearly 24 hours since hurricane harvey hit the texas coast. a look at the damage and the problems ahead. >>> and introducing an icon to a new generation. a group of bay area girls >>> in texas today harvey has been down graded from a category 4 hurricane to a tropical storm but the damage has been done. drone footage shows the damage that has been done in rockport, texas. here's reporter. >> reporter: more than 22 inches of rain is forecasts to flood parts of texas as hanchy weakens in strength but in no hurry to move on as it stalls over the loan star state. houston remains a huge concern after that city typically floods after two or three inches of rain. 130 mile-per-hour winds uprooted trees, tore houses apart and collapsed entire buildings, leaving streets littered with debris. wide-spread devastation is being reported by rockport. who said to write thei

. >>> rolling stone says shin nad o'connor is safe after alluding to suicide in a video.nonmuss post said she is receiving help. o'connor talk about her battle with mental illness in a video she posted last week from a hotel room in new jersey. >>> and "usa today" said scientists are confirming a recently discovered dinosaur was the biggest land animal ever. its fossils were found several years ago in argentina. researchers say the species see grew as much as 177 feet and weighed several tons. >>> still ahead, disney announce as whole new world when it comes to streaming its popular movie. sfx: cymbals they break only for the 100% complete and balanced nutrition of meow mix cat food. no wonder it's the only one cats ask for by name. i'm lucky to get through a shift without a disaster. heads up! you know what, don't worry about it. my bargain detergent couldn't keep up. it was mostly water. so, i switched to tide pods. they're super concentrated, so i get a better clean. i mean, i give away water for free. i'm not about to pay for it in my detergent. number one trusted. nu

suited madam nad people have something to say they always seem only to say that you said it in your head you see her hollands and she says not only did. not press the change. in the i think if. you want. to. go with the let's be fair i mean. can we strike would you really enjoy. when you know you're clever the link for a poem was what bush was. until march yes and it would fall off. to the presidio it would have been. there. is probably always e.g. viewings going up when the exam point you don't see vehicle precision a day or more but i keep the. days rather beautiful as a few who do. i had the area as if you wish but you certainly know foremost. by implicitly bill i mean even a proper supreme court for going to help you show me that also but don't come a point when you know i'm wait for me if he joins with you there was all of its ability to women be a super bowl before the snow and it went out glutinous and it would seem to get the local national to a conclusion the only scene losing because a. he she will. be left with a total total guess at least seem to get how do. i didn't say beca

suited madam nad people have something to say they always seem only to say that you said it's getting here that you see her hollands as she said not only did. not that's the. way to go don't you think if. you're going. to. talk away like before i mean. when we started could she really enjoyed that. when you know you're clever the link for a poem was what pushed while. until march yes something would fall off. to the presidio it would have been. there. is probably always e.g. viewings going up in window don't you don't see vehicle precision a day for more but i keep the watch. overlays rather beautiful as a few who do. i had the area i drew dollars if you wish but you certainly dodge no small motion. by implicitly bill i mean even a purpose or political for going to help you show me that also but don't come a point when you know and wait for me if he joins with. all of its ability women being a super bowl before the snow. and it would seem to get the local national coverage to a conclusion only seen lizzie as a. he she. was a total total guess at recent ticket how do you choose i didn'

and really, it is starting pretty nice nad bright across most areas.e, fine start from the south—east, the midlands, wales. a couple of showers there, around the lake district, maybe a few dotted around in northern ireland and western scotland, but on the whole, a nice start to the day. and here is that overnight rain moving away towards the north—east, off the edge of the screen — good riddance. now, as far as tuesday morning, and the second half of the morning and the afternoon is concerned, showers are actually going to be brewing inland. so it is not a completely dry day. take a brolly if you are out for any lengthy period of time. sunny spells, plenty of them, yes, and feeling quite warm, but there will be showers breaking out. how are we doing compared to the rest of europe? well, london will be warming up to 2a degrees. we're on a par with paris, but some storms around here, similar to warsaw and moscow. but hotting up across spain and portugal, and in italy and rome, there, temperatures up to around 35 degrees celsius. anyway, back home, tuesda

suited madam nad people have something to say they always seem only to say that you said it in your head you see her hollins as he says not only did. not that's the beauty. in the i think if you go from. i'll go with the let's be fair i mean. can we show you could she really enjoy it. when you know you are the link for a poem. what bush was. until march yes and it would fall off. to the presidio if you want to know what. is will be always e.g. if you are laying still going up a window don't you don't see vehicle precision for more but i keep the watch. overlays there for the fools a few who do i bet i had the area as if you wish but you certainly know foremost. by impulse and believe me even a proper supreme leader of a corpse were going to help you show me that also but don't come a point when you know i'm wait for me if he joins with. all of its ability to women be a super bowl. and the lieutenant and it would. be local national coverage to a conclusion only seen lizzie as a. he she. was a total total seem to get how do you choose i didn't say because of age a million plus clothes that

suited madam nad people have something to say they always seem always to say that you said it in your head you see her hollows as she said not only did. not press the to. think don't you think if. you want. to. go in the lobby for me. being watched by you could she be related to the. when you know you're there for the link for a home or. who work for while. there are just some that would fall off. to the presidio if you want to get. there. is probably always e.g. if you are laying still going up window don't you don't see vehicle could be a vision a day for more or less keep the. days rather beautiful as a few who do. i had the area i drew dollars if you wish but the more you side with no form. by impulse and believe me than a proper supreme court for going to help you show me that also but don't come a point when you know i'm waiting for me if he joins with you there was all of its ability to women be a super bowl before the snow and the lieutenant and it would. be local national coverage a conclusion only seen lizzie as a. he she. was a total total guess decay had to choose i didn't

suited madam nad people have something to say they always seem always to say that you said it in your head you see her hollows and she said it's not only to. not trust that. the if you don't if you're going. to. go into life before i mean. can we show you could she really enjoyed that. when you know you're there for the link for a poem. what bush was. until march yes a little before. you remember to do it what happened. is probably always e.g. if you're laying still going up when the exam point you don't see vehicle could be a vision a day or more but i keep the old. days we have a beautiful as a few who do i feel. i had the area as if you wish but you certainly know foremost. by the impulse and the i'm even a proper supreme leader of a corpse we're going to help you show me that also but don't come a point when you know i'm waiting for me and he joins with you there was all of its ability to women be a sleeping pill for the soul and it went a little too now and it would seem to get the local national to a conclusion only seen lizzie as a. he she. was a total total seem to get how do

. >> spread a narrative that where white national neo nads szi tha ridiculo ridiculous. >> reporter: police led the free speech group off the police wagon and on foot. nbc boston jonathan was in the middle of it. >> two trump supporters escorted out. here we go. are you okay? what's your name. >> reporter: with the free speech group gone, counter protesters burned a confederate battle flag on the steps of the state house. president trump said looks like many anti police. >> 99.9% of the people here are here for the right reason to fight bigotry and hate for the most part today. >> reporter: some were members on anti groups. >>> tonight in philadelphia, controversy continues over former mayor and police commissioner frank rizzo. vandals splashed paint on this mural in the italian market overnight. nbc 10 andrea joins us with more on the latest display on vandal li -- vand vandalism. >> the paint remains but the graffiti that includes anti police sentiments has since been removed. residents say opposing the former mayor and police commissioner is one thing but vandalizing property is t

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and really, it is starting pretty nice nad bright across most areas. fine start from the south—east, the midlands, wales. a couple of showers there, around the lake district, maybe a few dotted around in northern ireland and western scotland, but on the whole, a nice start to the day. and here is that overnight rain moving away towards the north—east, off the edge of the screen — good riddance. now, as far as tuesday morning, and the second half of the morning and the afternoon is concerned, showers are actually going to be brewing inland. so it is not a completely dry day. take a brolly if you are out for any lengthy period of time. sunny spells, plenty of them, yes, and feeling quite warm, but there will be showers breaking out. how are we doing compared to the rest of europe? well, london will be warming up to 2a degrees. we're on a par with paris, but some storms around here, similar to warsaw and moscow. but hotting up across spain and portugal, and in italy and rome, there, temperatures up to around 35 degrees celsius. anyway, back home, tuesday

even though they have a healthy diet and maybe taking multivitamins, which women have low levels of nadd the miscarriages. several leading supermarkets have moved salads and savages from the shelves because they could contain dutch eggs contaminated with a banned insecticide. the british food standards agency says that 7000 —— 700,000 such eggs have been distributed over the uk, is significant distributed over the uk, is significa nt increase over the initial estimate of 21,000 eggs. danish authorities said that many eggs have been distributed around denmark. dumped and discarded. this belgian farmer has had to destroy notjust his eggs but his hens as well. the produce contaminated with fipranol, an insecticide which is banned for use in the food chain. but that's where it has ended up on a potentially massive scale. translation: you cannot put your eggs on the market for three months. and so i took the decision to kill the animals because it is really too expensive. the company which came to clean and treat the red lice with a so—called organic product really used fipranol. we have all

. >>> there is one place to find art owe fish nad owes around the bay area this weekend.ws was in fremont for the fremont festival of the art. thousands of people packed downtown streets and purchased a piece oor two. it is promoted as the largest free street festival west of the mississippi and some people come back year after year. >> yeah, we come to the fremont festival every year. it's a great opportunity to run into friends. there is always amazing work. >> this is the 34th year for the event which also features live music, food, beer and wine, street performers and fun for the kids. >>> nonprofit group teamed up with north face to make climbing accessible to people with disabilities. abc7 news was in san francisco for the launch of climbing initiative at planet granite. they are working with staff and climbing gyms across the country to make them aware of needs of disabled athletes. it is intended to find a way for people in wheelchairs to injured veterans who want to learn to climb. >>> a 9-year-old space movie fan is chasing a job at nasa. jack davis from new jer

this led to nad, it is an energy source.ad bypassed the genetic mutation we re had bypassed the genetic mutation were found in the human.” apologise, there is some microphone noise. if women are trying to get pregnant or are noise. if women are trying to get pregnant orare in noise. if women are trying to get pregnant or are in early pregnancy, what is the advice with taking b3? at this stage, we would say take the recommended amount that appears in a pregnancy multivitamin. we cannot advise more than that because we have not done the research. but we are embarking on that research so we can identify women who do have low nad levels at risk of having babies with birth defects, and we will do more work to see what sort of levels of the vitamin, b3, would be safe to the event birth defects and multiple miscarriages. how can you get 33 if you are not taking supplements? what food? you probably won't get enough just from food. but you can get niacin from red meat, poultry, fish, legumes, his and lentils, and vegetables. —— peas.

is violating law and so it has to end the nation magazine or it's action dot org and watchdog data nad are just some organizations that are sponsoring this petition so far fifty thousand people have signed a document in hopes of ending the u.s. is involved meant in the syrian war and washington national banks are. former blackwater c.e.o. erik prince has proposed a two year contract to send nearly five thousand additional troops and almost one hundred aircraft to afghanistan president from recently recruited prince to develop proposals replacing american troops with contractors in the country are to use jacqueline vogel as further details that i. meet erik prince the founder of blackwater a private military company with a controversial reputation with its legacy you might expect prince's career to be over but this cannot be farther from the truth there's no backlash for him no shame the man's gun for hire business is booming what i care about is its taxpayer is that large you wasting food say five billion dollars a year in afghanistan i don't think it's appropriate to pull out complete

she'snly the second woman ever nad deputy chief. he will be introduced on thursday. >>> new at 6:00, economists at stanford say obamacare is not having a negative effect on jobs. that was one concern raised by critics based on ear projections by t congressional budget office. three economists studied the law's impa and found there was no major effect on the u. labor market as a result. the predicted positiv and negative effects seemed to mostly balance each other out. another reason is that the predictions were made based on changes to medicaid and didn't look at the impact of iurance exchanges. they suspect the trends will continue in the future if no changes are made to obamacare. if it is changed, it's hard to predict how that would affect the labor market because it would likely change medicaid an health insurance. >>> two bay area countie have cases of west nile virus. last month, it was foundn two dead birds in contra costa county. this is considered a late start to the west nile season. >>>ow to the developing story of the le

. >> that was that gre nate nad right there. >> a constant treem of coming and going. >> this pot smelling thing, they smoke the pot or whatever and so much noise going on. >> police say they have responded to this before, so they're not surprised by this big scale crackdown, approve of it with the suspicious activities taking place. >> someone pulling up and someone handing something down to somebody there and them leaving. >> and we also learn learned that similar activity took place in public housing and individuals' homes. s' homes. san francisco police confirming a statement on the operation, said for the safety of all involved, we are are not able to release any information at this time. this time. once operations have concluded, we will provide information about the laum activities. we saw at least six people detained in friction and in daly city, we saw three men being walked out to the van, but wouldn't say why. >> i'm glad the police came. e police came. it needed to be put to a stop. >> we are told there will be a press conference thursday morning, involving several agencies, in

donald trump was like a pirate sailing nad flag of convenience when he ran as a republican. doesn't really have any republican values. he's more of a status and authoritarian. he doesn't believe in personal freedom or limited government. and i want to introduce john to one simple concept. congress is a co equal branch of government. they don't represent the trump hoard. they represent their individual states. they represent the issues and these are their constituents and so mitch mcconnell has a caucus in the senate where they have 52 members and they have a variety of different interests and drivers for their behavior. so they're not all going to say whatever crazy thing came off of donald trump's itchy twitter finger, i'm going to alter everything. these guys represent their people. they are not there to serve donald trump. they're a coequal branch of government. i know the constitution is an inconvenience for the trump world but it's something that folks like john should refamiliarize yourself with. >> you just don't get what's happening out there in america. because you'

preventing miscarriages, researchers in australia found two gene to be deficient in a co enzyme called nad. normal organ developments when they tested the mutation in mice they found the defects could be prevented but more research is still needed. >>> oprah opens up about her weight struggles. she is done with obsessing about her weight. in a candid interview for this sent issue of vogue magazine, she said her high profile weight structures. >>> coming u. a founder of netflix wants to make going to the movies affordable again >> heading to break with what we could call outside, yeah, this is kind of we'll get you through it. 5:42 is the time. 73 is your temperature. did you know slow internet can actually hold your business back? say goodbye to slow downloads, slow backups, slow everything. comcast business offers blazing fast and reliable internet that's up to 16 times faster than slow internet from the phone company. say hello to faster downloads with internet speeds up to 250 megabits per second. get fast internet and add phone and tv now for only $24.90 more per month. our lowest pric

. >> i've got to tell you, i was watching a really super video with a man by the nad of atticus tysont of a sales force.com presentation, and he says that intuit turns drudgery to delightful for taxes? >> i couldn't have said it better you're absolutely right. atticus is absolutely right. we know no one wakes up every day excited to do taxes. so our goal is to take the magic of technology and artificial intelligence and make it go away and still put the maximum money in their pocket. that's what we wake up every day excited to do. >> i need you to talk about this sos service. i use your -- we use your intuit in our bar this has got to be stg that people love. >> you know, jim, it is. there are 155 million people who file taxes with the irs every year about 85 million go to someone to do their taxes for them whether it's a tax store or a cpa. and yet they typically have this one nagging question, and if they had that question answered, they wouldn't have to pay hundreds of dollars to get their taxes done, they could get it done for free, or as much as $40. we brought the human expert i

. >> shev rad nad za warned today that the right wing coup would have tragic consequences. >> it is the civil war. >> extraordinary drama in moscow tonight. scenes of destruction, of fire, even of blood on the streets. >> four people died it, crushed by armored vehicles. >> speculation he's being held in moscow, 50,000 people gathered at the russian parliament building. >> gorbachev wasn't that popular at that point, but these people were even less popular than gov chev. if they mounted a coup in 1989 or early 1990, he might have fallen and the new soviet union would have been quite different. but there were already new legitimate figures that the russian people were supporting and were expecting a lot from. >> around 50,000 supporters of boris yeltsin gathered to chant their support for the man who is now carrying the battered banner of liberal reform. >> boris yeltsin had been popularly elected as president of the russian federation. he was emerging as an alternative power to the communist party leaders. >> let me put on my glasses here for a moment and read you a piece of wire copy t

it was domestic nad by the north korean issue, an issue that certainly isn't over. and what an extraordinary few days of diplomacy it's been. it really started with that vote at the u.n. security council over the weekend. it was unanimous to impose punishing new sanctions on north korea. and today north korean's foreign minister hit back saying that north korea would retaliate against those u.n. sanctions. didn't saw how, but mainly blamed the united states, saying that north korea is ready to give the u.s. a severe lesson if the u.s. attacks north korea. there's always an if in there. but it also said that we will never put our nuclear capability or our long-range missiles on any negotiating table. and it said there's no bigger mistake than the u.s. believing its land is safe across the ocean. now, many of these threats we've heard before, but object united states you will as this crisis escalates, those threats become all the more menacing. and the north korean had an international stage to make his threats. he was in the room with the foreign ministers of russia,

complicated at the same time i think you've got people here in the valley that are sort of snap owe fish nads and cheerleaders you have folks that are more on the facebook corner. i think what you thought a year ago, maybe even a year and a half ago, you really thought snap had momentum and had a chance to overtake facebook in part of its core audience. i think that whole strategy is very much in doubt now part of it has been, of course, instagram in particular is able to copy many of those popular features that snap had pioneered. i've got three teenage daughters. they're all heavy snapchat users. but they're heavy instagram users also it's an interesting time for snap going forward i think the analogy is going to be facebook? well, will it rebound or twitter and sort of struggle along as people worry about this daus and about the usage? i think that's an open question. >> yeah. a company hated that ing that a. is the smart business decision to step on the gas, start spending even more money where they can or try to save some dry powder >> well, i think you've got -- there's a couple ways i

live at the nad dak market site. stocks closing out august with a rally.ices positive for the month. nasdaq closing at a record high. here's what's coming up in the rest of the show the tech stock, this tech stock is up 30% in the last year traders are betting it's about to erase almost all of those gains. we'll tell you the name. the auto stock revving up. it may have had investors in a frenzy today we start off with bitcoin, up another 10% this week. that's giving rise to a number of bitcoin related products. one of the products has become very popular. >> the rise of bitcoin has given birth to not only new currencies, but investment vehicles and platforms that offer investors different ways to get exposure to the crypto currency without owning it this includes gray scale bitcoin investment trust which trades on the otc market it's up 300% over the past six months, the trust has gained well over 700% they also look at net asset value taking the number of bitcoin to fund hold divided by the number of shares outstanding which currently equals 423 but as yo

these flashing led shoes nad gentleman opinion.n be made to lighted up when you receive an e-mail, text or call. most people who wear them are dancers or performers but this trend is catching on with regular people who like to walk around with that. a pair costs 400 u.s. dollars. >>> unless you're tublly in disneyland's paint the night parade that's going to be the big no. next the seven things to know to start your day. >>> plus the new tax marin county residents could soon are paying for. >>> you're going to be hanging out in here. so if you need anything, text me. do you play? ♪ ♪ use the chase mobile app to send money in just a tap, to friends at more banks then ever before. you got next? chase. helping you master what's now and what's next. could be preventedrrent with the right steps. and take it from me, every step counts. a bayer aspirin regimen is one of those steps in helping prevent another stroke. be sure to talk to your doctor before you begin an aspirin regimen. from the moment you met you wantecomfort and protection

theater ticket can cost $12 to $15 by the time you nad popcorn, parking food. >> it's expensive. >> ii would pay for this. >> yes. >> i would pay for this. >> i don't know if i go to the movies enough. >> 10 bikz that's less than price of one movie though. >> it's paid for is taevl if you go to one movie a month. >> one movie. >> one thing with amc reason they're fighting this so hard they're afraid the business model is going to fail which we pretty much think it will. so then folks used to paying $10 a month might say you know what i'm not going to the movies period. i'm used to $10 or nothing. that's their argument. we'll see how it goes. >> i think this is to attract people netflix generation getting people out of the house watching movies mean the theaters watching movies i don't know what amc objection is. >> i need them to build better chairs. some movie theaters are comfortable and. >> how about the ones with the nice lounge chairs. >> do that and you can get more people. >> and adult beverage. >> add that in too. >> $20 a month you get beer. >> and popcorn. >> thank you so mu

sour te a te muerte y los problemas personal de le han in nada los me voys porque tienen que le han in nadv porque tienen que los me voys porque tienen que o los me voys porque tienen que porque tienen que porque tienen qurporque tienen quporque tienen qucp procesoporque tienen qusporque porque tienen que inyectarla. >>> quÉ bueno que estÁ hablando porque cuando era la callada era la mala de la pelÍcula lo importante la salud que el niÑo estÉ pero feblth y no tenga que in llego dpraergs para ptllego z problemas >>> veremos cÓmo jorge medina se fue >>> necesitaba un break para darme cuenta lo que realmente querÍa. ahora estamos estrenando este camino que me parece muy interesante. digo tengo muchos nervios, quÉ es mucho trabajo. pero el sentimiento estoy feliz. chuy lizÁrraga somos amigos de 24 aÑos yo confÍo en Él y el en mÍ. >>> jorge nos preparamos pa ra a apoyarte como solista >>> adamaris prÉstame la atenciÓn que vamos a otra nota >>> no canto nada >>> jamÁs creerÍa eso porque te harÍa un coro porque en bonito que digamos que culiacÁn participaron en una mega vooents en puente grande j

they've been living on the muscle memory in the case of nad ol of ferguson where you can bash the mayorst decade and so now, as i said i believe that a shift is occur ring and do i think that na dol will design? no. do i think they will get rid of her? no. this is all a bunch of pomp and circumstance to make us leave they want to do that on the left but she absolutely should step down. >> jon: with that i want to read a statement we just received from missouri democratic chair steven weber. it says the state senator's comments are in defensible. all sides need to agree there's no room for suggestions of political violence in america and the missouri democratic party will absolutely not tolerate calls for the assassination of the president and here is the line here, mr. jackson. i believe she should resign. again this is from the democrats you said this is just a bunch of hogwash. they're just posturing. >> yeah, they're posturing because look, they need people like nadol. the democrats they depend on the blacks and the party to raise hell, to be blunt, and to keep these things stirring