and this nova gene should have ideally the ability to act as a cancer gene which can put nasty kate the test this is left of votes and which maybe by itself might lead police and a target for target so meaning that if a patient has a tumor and in this to reduce this special kind of gene there's a high prevalence of metastasis absolutely we have now follow ups of 17 years and our partners to cation percentage just so the probability that a patient is high makes of it that later on in the tests is about 80 to 89 percent which is quite high and this gene is right here in this tumor sort of in a smaller than the genus basically is expressed at the 2 more rim ok meaning in these areas you will find those which are very more tired which can my weight which can invade the 4 into shills and they're the next year's cage but if i examined the tumor i'm not too sure if i'd take some example from inside the tumor he said in the middle so there are not so many genes so what is a diagnostic test i can use as a clinician in addition to the tumor based s.a.v. also developed a blood based essay. and

nova rtis. i can kind of make it out, but it‘s not very clear. in theatre the surgeon prepares the genehe retina at the back of the eye. the treatment delivers working copies of a faulty gene, rpe65. these are encased in a harmless virus, which breaks into the retinal cells. once inside the nucleus, the replacement gene kick—starts production of a protein essential for healthy vision. this is a life—changing treatment for patients, hopefully preserving and improving vision for decades. it should have the biggest impact with children, halting site loss before permanent damage is done. halting sight loss before permanent damage is done. this is very exciting. this is the first approved nhs gene therapy for an eye disease, but of course there‘s opportunities to use gene therapy to treat other diseases in future. so come forward... jake ternent from durham had his gene therapy a couple of weeks ago, and is back at moorfields eye hospital in london for a check—up. i hope that, you know, i can improve my night vision, which will be a major improvement for me in daily life, and maybe, possibly