novartis, juno and kite are companies competing in the market. novartis and they say they remain committed to the development of car-t therapies and remain well positioned to successfully launch ctl019 in relapsed -- that's the indication they're going for. they say they're still on track this doesn't effect their plan to file for approval early 2017, guys. >> to be fair they laid off 120 people, but they're still keeping and reintegrating 280 people into other functions. >> that's right. so they're really calling this an organizational shift, but you can see it's clearly spooked the market. some people interpreting this as them saying maybe this opportunity wasn't as big as we thought. >> okay. let's chat more about this and bring in hans bishop, ceo. hans, thank you so much for joining us, given the stock reaction to the novartis news. >> my pleasure. >> there are some questions about car-t treatments in general when you guys had a setback for your treatment for acute likucute acute, that's thrown doubt on the whole space, we saw stocks react a

one operating regime, but it has one innovation in it that the standard steel propeller company novartis and is ready by the time lindbergh, who in his memoir says i want a metal propeller for the "spirit of st. louis," and what he means is the standard steel ground-adjustable pitch propeller. and what i mean by that is that you can't change the angle of the blades in the air, but if you need to change the pitch on the ground, you can loosen two rings, change the pitch for whatever setting you want it to be, so they can get you off the ground with the heavyweight of the fuel but give you enough cruise efficiency to get across the atlantic. so, it's a compromise. in many ways, the airplane overall is a compromise to get lindbergh across the atlantic ocean. so, the flight itself. lindbergh didn't have advanced navigational tools like a gps. he did have a compass and a method called dead reckoning, where he would use the stars to plot his path. he's going to fly the circumpolar routes across instead of flying over the shipping lanes. he's flying a much shorter distance over the curvature of

intellia is a joint venture with andother company, caribou, novartis, a huge pharmaceutical conglomerate, a bunch of venture similarly,and several hundred million dollars. another company in boston. companies -- countries do not read too much to these people, they move all over. bayer,llion deal with and lots more money. as they say. so that is the context. i want to put the big question, as i see it. government regulation, and control, of which people, by which people, and for which people? ,his is something where we can i think, tito and biocurious have an interest in this as well. i think some of us have a philosophical interest, some of us have a financial kind of interest. social equitye a interest. some of us just have safety interest. but what can we do, what should , when should we be able to do it, who decides, and how do we decide? it is kind of a big deal. i am sure that biocurious does not want to generate anything that is going to be a pathogen that gets out of the lab that causes damage. in fact, i would like to hear you talk about that maybe at some point. what, if any, pr

one operating regime, but it has one innovation in it that the standard steel propeller company novartis and is ready by the time lindbergh, who in his memoir says i want a metal propeller for the "spirit of st. louis," and what he means is the standard steel ground-adjustable pitch propeller. and what i mean by that is that you can't change the angle of the blades in the air, but if you need to change the pitch on the ground, you can loosen two rings, change the pitch for whatever setting you want it to be, so they can get you off the ground with the heavyweight of the fuel but give you enough cruise efficiency to get across the atlantic. so, it's a compromise. in many ways, the airplane overall is a compromise to get lindbergh across the atlantic ocean. so, the flight itself. lindbergh didn't have advanced navigational tools like a gps. he didn't ha have a compass and method called dead reckoning, where he would use the stars to plot his path. he's going to fly the circumpolar routes across instead of flying over the shipping lanes. he's flying a much shorter distance over the curvatur