shares of novartis getting a pop.p about 1% in early trading back over to you >> thank you very much i feel like amazon has not found a market it doesn't want to disrupt yet. >>> there are several economic reports on the docket. the ism manufacturing index is out at 10:00 a.m. eastern along with september construction spending november auto sales come out throughout the day dallas fed president rob kaplan, philly president harker and randy kaurl randy quaufrl ran randy quarles are also speaking today. >>> some stocks to watch are coming your way after the break. >>> and the countdown is on, 24 shopping days left until christmas. we'll tell you which retailers are best positioned heading into the rush >> and we have a christmas countdown clock that's accurate as well. last time we put one up, it was out. what's team spirit worth? (cheers) what's it worth to talk to your mom? what's the value of a walk in the woods? the value of capital is to create, not just wealth, but things that matter. morgan stanley or a little in

novartis is one of them.ed against in an intellectual property case. -- keep anon a con eye on akon and on the car companies. china is curtailing car production. this is a small fraction of the number of cars that is sold. and daimler.n vw it is thursday. three stocks are going ex dividend. on,ones you want to focus batts and bt. a fairly mixed story in europe. the market open is four minutes away. this is bloomberg. ♪ until theinute to go cash trading. equity issues and the factors you need to put into the market with money. i want to highlight the fact that the pound is rallying this morning against the dollar. think about when you look at the market open in london this morning. the pound up. generally, ftse down through the nikkei down because we had decent retail and production data out of japan today. the other thing i want to highlight is the crude is gathering this morning. trading up by around .5%. interesting inasmuch as it may affect the commodities story. s&p 500. it was not a great session if you

. >>> novartis says the fda has given primary review status for one of its cancer therapies. >>> somether stocks to watch, roche striking a deal to buy u.s. cancer drugmaker ignyta for 1$1.7 billion roche will pay 27 bucks a share, a 74% premium to yesterday's closing price. ignyta has several drugs in development that use gene therapy to kill the understand lying diseases of the growth of cancer tumors. >>> gbc sealed a deal to buy rival ladbrokes for 5$5.3 billion. gvc owns the sporting bet, foxy bingo brands ladbrokes merged with another rival in 2015, so some movement on the againibgambling side of . >>> it is a busy day ahead on the economic data calendar november durable goods and personal income and spending are out at 8:30 a.m. eastern that's followed by november new home sales and the final reading on december consumer sentiment at 10:00 a.m >>> still ahead on the show, flying high. it's been a turbulent year for the airlines, will 2018 bring sol frie some friendlier skies? we'll breaking out our playbook for the airlines ahead. >>> first the retail rush is on. just two shopp

. >>> "right this minute" is brought to you by -- novartis. w? (grunts of effort) can we do this tomorrow? if you have heart failure symptoms, your risk of hospitalization could increase, making tomorrow uncertain. but entresto is a medicine that was proven, in the largest heart failure study ever, to help more people stay alive and out of the hospital than a leading heart failure medicine. women who are pregnant must not take entresto. it can cause harm or death to an unborn baby. don't take entresto with an ace inhibitor or aliskiren. if you've had angioedema while taking an ace or arb medicine, don't take entresto. the most serious side effects are angioedema, low blood pressure, kidney problems, or high potassium in your blood. ♪ tomorrow, tomorrow... ♪ when can we do this again, grandpa? well, how about tomorrow? ask your doctor about entresto and help make tomorrow possible. ask your doctor about entresto >>> closed captioning provide by -- goldradiance renewal exfoliates then our triple blend of moisturizers helps prevent dry skin. gold bo

as first reported by cnbc, the talks had been with mylan and a unity of novartis.amazon's plans are not yet clear but may be about the company taking a role in drug purchasing, competing against drug distributors. shares of mylan got a lift on the news in afte showes trading. >>> kroger's heavy discounting leads to higher sales. the supermarket giant reported stronger than expected earnings as promotions brought more customers into its stores. the company said sales were especially strong on black friday. kroger sees that momentum continuing. it is forecasting upbeat results for the holiday period. shares rose 6% to $25.86. >>> same-store sales fell for the 24th executive quarter at seri but the struggling retailer said a smaller footprint and focus on stores that only sold appliances and mattresses could help financial performance. shares initially rose following the news but lost those gains, closing down 3% to $4.08. >>> barnes & noble, on the other hand, saw its loss widen as fewer customers made purchases. the bookstore chain experimented with selling toys and

. >>> cnn heroes every day people changing the world is brought to you by novartis and subaru.of the year at cnnheroes.com and on facebook messenger. this tomorro? (grunts of effort) can we do this tomorrow? if you have heart failure symptoms, your risk of hospitalization could increase, making tomorrow uncertain. but entresto is a medicine that was proven, in the largest heart failure study ever, to help more people stay alive and out of the hospital than a leading heart failure medicine. women who are pregnant must not take entresto. it can cause harm or death to an unborn baby. don't take entresto with an ace inhibitor or aliskiren. if you've had angioedema while taking an ace or arb medicine, don't take entresto. the most serious side effects are angioedema, low blood pressure, kidney problems, or high potassium in your blood. ♪ tomorrow, tomorrow... ♪ when can we do this again, grandpa? well, how about tomorrow? ask your doctor about entresto and help make tomorrow possible. i started volunteering for (victorinational parks.s twelve, i go out and demonstrate to people what

the alling comes in the lawsuit regarding novartis.n was prescribed a generic version a drug and she claims it caused her children brain damage. >>> getting ready for the wrapping paper and boxes. but some items can't be recycled. ribbons and bows are not recyclable. and things like plastic and paper need to be properly separated before recycling. >> if it's too contaminated they don't separate it. it takes too much time. it will come off the end of the line and some of the things will end up in the trash. >> experts say the u.s. gets $5 billion a year from china for recycled materials used to produce products there. but this month, the chinese government announced it will stop accepting recycled shipments with more than 1% contamination. >>> sacred heart is continuing the toy giveaway. the event kicked off yesterday with thousands showing up to pick out toys and books. the family signed up for the giveaway earlier this month. and last night organizers were scrambling to collect more toy donations. >> the need is greater because we're

visit geico.com for a free quote and by novartis. i don't have my keys. (on intercom) all hands. keys again. they are on a silver carabiner. oh, this is bad. as long as people misplace their keys, you can count on geico saving folks money. fifteen minutes could save you fifteen percent or more on car insurance. (hard exhalation) honey? can we do this tomorrow? (grunts of effort) can we do this tomorrow? if you have heart failure symptoms, your risk of hospitalization could increase, making tomorrow uncertain. but entresto is a medicine that was proven, in the largest heart failure study ever, to help more people stay alive and out of the hospital than a leading heart failure medicine. women who are pregnant must not take entresto. it can cause harm or death to an unborn baby. don't take entresto with an ace inhibitor or aliskiren. if you've had angioedema while taking an ace or arb medicine, don't take entresto. the most serious side effects are angioedema, low blood pressure, kidney problems, or high potassium in your blood. ♪ tomorrow, tomorrow... ♪ when can we do this again, g

some biotech names >>> i think novartis is the best one in terms of waking up to the idea that people will live long lives, and that aging itself is a disease rather than the diseases of aging. gsk in the uk is a good example of a company that's forward thinking but most of them are private some of them will go public in the next year. it will be interesting to watch. on the big sort of international view at the moment, the eu, you don't think the growth pick up will be long lasting it's a brief kind of reprieve as it were. >> it's a dead cat bounce, in my opinion. you're seeing about 2.5% forecast for the european union next year and then 2% to 3% growth after that. i think most has been generated by monetary stimulus and also a bounce from the bottom i would say they're going back into trouble already we're seeing that. you're seeing the polish issue the fact that the economies are now ganging up together. and you're seeing catalonia still being a problem and we have brexit to deal with and the italian elections. there's all sorts of stuff that could be fracture points in the next y

the big names, novartis, hsbc is down. nestle is down, even within acquisition.rs are going to the above to smile. it is only a drop of 0.4% but it is a very heavy stock. also the miners down today. glencore. rio tinto is down. i suspect that if you scroll through the losing side, you are going to see almost all miners on the side. it you look at the winning side, you don't see anybody connected to commodities. you see a lot more of the defensive stocks. you are going to see some of those utilities and consumer staples stocks on the upside but really going to be very few winners, as far as today's trade is concerned. guy: matt, the dax is still waiting to open. elsewhere, we are getting some numbers that are shown you the extent of the drop. the dax is likely to show the biggest drop this morning. many sectors in negative territory. many stocks trading to the downside. we are expecting the dax to open down a full percentage point. london looks like it is outperforming. we will talk a little bit about the pound later on. this comes after we saw a fairly decent sel

"cnn heros: an all-star tribute" is proudly sponsored by novartis.) can we do this tomorrow? if you have heart failure symptoms, your risk of hospitalization could increase, making tomorrow uncertain. but entresto is a medicine that was proven, in the largest heart failure study ever, to help more people stay alive and out of the hospital than a leading heart failure medicine. women who are pregnant must not take entresto. it can cause harm or death to an unborn baby. don't take entresto with an ace inhibitor or aliskiren. if you've had angioedema while taking an ace or arb medicine, don't take entresto. the most serious side effects are angioedema, low blood pressure, kidney problems, or high potassium in your blood. ♪ tomorrow, tomorrow... ♪ when can we do this again, grandpa? well, how about tomorrow? ask your doctor about entresto and help make tomorrow possible. >>> hey, welcome back to "cnn heroes." now, have you donated yet? come on. let's help all of tonight's heros raise $50,000 with every dollar matched by subaru. if you do it now at cnnher

cnn heroes an all-star tribute is proudly sponsored by -- novartis. can we do this tomorrow?help more people stay alive and out of the hospital than a leading heart failure medicine. women who are pregnant must not take entresto. it can cause harm or death to an unborn baby. don't take entresto with an ace inhibitor or aliskiren. if you've had angioedema while taking an ace or arb medicine, don't take entresto. the most serious side effects are angioedema, low blood pressure, kidney problems, or high potassium in your blood. ♪ tomorrow, tomorrow... ♪ when can we do this again, grandpa? well, how about tomorrow? ask your doctor about entresto and help make tomorrow possible. ask your doctor about entresto and i am a senior public safety my namspecialist for pg&e. my job is to help educate our first responders on how to deal with natural gas and electric emergencies. everyday when we go to work we want everyone to work safely and come home safely. i live right here in auburn, i absolutely love this community. once i moved here i didn't want to live anywhere else. i love that pe

on for a year and seven months opposed to a one-year and they have joseph jimenez, former ceo of novartis>> good man. if you look at the business units nelson wants, another way to run the company he's always wanted the divisions to be more competitive against each other and i wanted the small scale they had gotten into and got out of, which is reminiscent of what unilever. >> ed garden, when we talked about delivering alpha who's making decisions at this company? tell me who is reporting to who and making decisions he's going to be pressuring them every single board meeting. >> it does seem like the cincinnati bengals was running back by committee. rbc. you don't want that in fantasy and don't want it in reality. >> no. there it is. quiet end to a very loud battle. up next, we've got jim's mad dash and count you down to the opening bell which looks like we'll have a strong open when you look where futures are this -- as a result it would seem the expectations. we're going to get a signed tax cut maybe by the end of the week. >> holy cow. >> more "squawk on the street squt straight ahead.

therapeutics, biomarin and bluebird bio in that space new form of immunotherapy, investors will be watching novartisapeutics we'll have many of the companies' ceos on monday including on "closing bell," spark therapeutics jeff marrazzo >> i can imagine on the sage therapeutics drug you're going to have to take that forever we're not talking about a cure that you take then you're cured of depression and you don't have to take it anymore, right? >> that's a really good question, bill, of course it's yet to be seen this is a short trial in 89 patients jeff jonas, the ceo, is talking about potentially the ability to take it for a short period of time. >> wow. >> like an antibiotic he was quoted in one story today, if patients' depression comes back, they can start taking it again all the questions will have to be answered in larger and longer clinical trials. >> that's amazing. >> wow you think of current antidepressant treatments, you have to be on them forever. >> exactly it's a chemical imbalance they're adjusting at that point. that's amazing. >> cool stuff, meg, thanks. >> thanks, meg see you monda

is said to be in talks with generic drugmakers, specifically with mylan and the generic unit of novartisenter drug sales or home sale business, but 10% of pharmacy profits are at risk if amazon moves in. those stocks moving higher. cosmetics down by 6%, missing estimates. thiss down 13% overall year. qualcomm running down 1.5%. broadcom said to stall making a better bid to the current bid is $105 billion. that is about $70 in cash and stock. stock trading below at $65. they will wait until march's board meeting at qualcomm. and the repertory issue very complicated. jonathan: thank you. nobody thinks the m&a action in that sector is over. in d.c., senate republicans, they have handed a lifeline by a couple of individuals. senator ron johnson, previously holding out against the tax bill, now says he will vote for it. senators corcoran and flake are still holding out. joining us now is bloomberg's kevin cirilli. re: hawks slowly capitulating this morning -- are the hawks fully capitulating this morning? kevin: looks like momentum is on the side of republican leadership and the president. th

>> novartis made some comments a couple days ago in an investor meeting hosted by our firm, they hadiscussions with amazon. a potential play, if you wanted to look at this more transformatively, could be amazon saying, hey, walmart is doing the $4 generic drugs in store. why don't we do something like that with online shopping and mail order let's say they work with mylan or one other >> do you think they need to own a mylan or -- >> no. no >> straight partnership stuff. >> straight partnership. the threat would be -- i'm not saying they would do this, but this could potentially happen. they disintermediate the pb marks because they negotiate the generics, they do the sailing, all of it, end to end in the drug supply chain. you know walmart is going bricks to clicks, and amazon is going clicks to bricks, but that's a good play for them at this point know vnovartis hat confirmed anything that ambitious, but it's a possibility. we don't know. >> amazon, god not an industry where if we don't talk about something happening, we don't go amazon. >> i know. they're likal ove athe overhang t

if a drug doesn't work novartis announced with its drug $475,000 if it doesn't work, then they will cover're going in that you need proof that something is working, whether it be the system or the drugs that we're paying for? >> oh, absolutely. especially the drugs that become very expensive when there's a failure there should be accountability for it, and the manufacturer should be doing something to pay back in some way or the other. these value-based contracts are growing everywhere, and more importantly, value-based partnerships, which is a longer term conversation with managed care is the way to go. then everybody works on population health and tries to reduce the overall health care cost, which is where this merger is hopefully going g to. >> right in the discussion, though, about high drug prices for one is that after so much political attention as well as just mainstream attention, it really focused on the pbm's pbm's don't exist in this sort of equation really, though >> pbm's have a very good role to play. i think the industry has been fighting the pbm's unnecessarily. i think t

. >>> novartis said the fda granted priority review status to its combo therapy treatment for stage threeelanoma priority review expedites drugs that are expected to have a significant impact on the treatment of a disease >>> back to today's top washington story congress passing a spending bill keeping the government open and setting the stage for a tax cut signing. kayla tausche joins us from capitol hill with the latest it looks like everybody will get to go home for the holidays. >> and they may already have it was the last major move of the session when both chambers last night rushed to pass this short-term spending fix. it keeps the government running for a month. all the lawmakers were able to head home for the holidays the bill heads to president trump for a signature. we'll wait for that and the tax bill signature as well rand paul voiced concern about the package because it lifts the spending caps to fund the bill he spoke last night on the floor wanting not to lift those spending caps and chastised his colleagues for supporting a move that would continue to keep debt limbs unch