we are only developing so-called orphan drugs where, you know, less than 200,000 patients in the u.s. and so, indeed, we have to deal with very small patient populations, actually most of our drugs are for so-called ultra orphan disorders. yeah, less than 10,000 patients. >> okay. >> but we make a very big difference in the lives of these patients. and since -- and since there are no other alternatives to our treatments the insurers, the payers are willing to pay substantial amount of money to help these patients have their quality of life improved. >> okay. now in terms of this vimizine, everything, all the documents, you can read about this company. apparently the panel will have a lot of questions about the data,

may the lord have mercy on your gas sniffing, orphan-beating soul.st be with you. ( horn honking ) hey, ned. i just read about your park in that horrible aaa magazine. ooo, ned, look who's here. it's that girl you don't like... not. ( laughing crazily ) hey, your hair's grown back real nice. it's a wig. and let's never speak of it again. so what happened here? how about i explain it to you over a cup of coffee? that is, if you're willing to give me another shot. are you sure you want to do this, ned? i'm sure. so, how about a movie tomorrow night? sounds great. ( door closes ) i think ned's going to be all right. [captioned by the caption center wgbh educational foundation] morning. morning. sleep okay? mm-hmm. great. sure. last night, me wanting to try that stuff out of the kama sutra, was that fun for you or kinda racially insensitive? yeah, just because you're in bed with an indian woman, you think that gives you permission hey, if you can find a book called weird sex with white boys, i'd be okay with that. no, no, you have such beautiful eyes. ha

these are all orphan drugs, which means biomarin can charge a great deal for them, because they save the system money, and the insurers welcome these. together these drugs are racking up over $500 million in sales. they have a lot more room to grow. a terrific late-stage pipeline with an enzyme replacement drug for another type of mps that could be approved by the fda in the -- maybe even the first quarter of next year, might do $650 million in peak sales, two more orphan drugs that are either in or about to start phase three development including a treatment for pompeii disease, an often fatal disease, which could generate $500 million in sales. working on treatment for breast and ovarian cancer that targets the dna of tumor cells. stock's up 28% since we heard from the company last, in june, up 245% since i got behind it. that's right, 245, not a mistake. we've got to find out more about this company. welcome back to "mad money." thank you so much. j.j., i try to get them all in because you -- unlike most of the drug companies i deal with, you've got multiple things. this is not a

we do it so russia will be without orphans we tell our own stories we were orphans ourselves even drug addicts we lived in basements but people took us in and we changed there's nothing scary about it you see we're normal healthy people. always had a dreadful smell the stench of homeless children. simply beyond description when we took those filthy teenagers from the basement. people who. died in it. it's ok everything's fine. under special. he's one of the first guys who came to the republic of pilgrims. just changing your clothes right. to change to eat as far as i remember. last year i came to the pilgrims when i was twelve i lived on the street since i was six right where we are now from your business and i spent nights in basements i saw drug addicts and even sniff glue. if they haven't come. into our basement about time to feed us i think i would be in prison just like so many of my friends this young. my life has changed completely at the very least i'm alive i'm studying at the conservatory now playing music which is what i like. in the orphanage thirty nine times i felt nobody

we do it so russia will be without orphans we tell our own stories we were orphans ourselves even drug addicts we lived in basements but people took us in and we changed there's nothing scary about it you see we're normal healthy people. always had a dreadful smell the stench of homeless children. simply beyond description when we took those filthy teenagers from the basement. people who got into my car asked if something a died in it. it's ok everything's fine. under special. he's one of the first guys who came to the republic of pilgrims. just changing your clothes right. to change to eat as far as i remember. last year i came to the pilgrims when i was twelve i lived on the street since i was six right where we are now. i spent nights in basements i saw drug addicts and even sniff glue. if they had. come to our basement about time to feed us i think i would be in prison just like so many of my friends is you know. my life has changed completely at the very least i'm alive i'm studying at the conservatory now playing music which is what i like. in the orphanage thirty nine times i fe

some from orphan otters savedded by dr.> these were or fans that we came in that we reared up to a point where they could handle solid food. >> reporter: dr. murray has worked to save otters for 20 years. people love them because they're so cute but that's not necessarily their nature. >> no. i like to consider them sea wolverines. they are not very friendly. they're rather pugnacious. >> reporter: since otters learn from their mothers how to hunt and feed, orphan pups are unlikely to survive in the wild so the orphans rescued by the aquarium have to be taught. a decade ago the aquarium tried using human surrogates who play the role of otter mother, even showing pups how to dive for shells and break them with a rock. you gave up on that? >> we're not very good sea otters. we're not only not that cute but we just can't do what they do. >> reporter: it turned out some of the female otters part of the aquariums otter exhibit make excellent surrogate mothers. so the otters in your aquarium are much more than something just to l

you're 74 years old but you stay young by drinking the tears of orphans, starving orphans appare apparently>> virgin orphans. >> we hope they are. >> what do you think of the findings? >> do we think they want a crap about our living. they only want our views. >> if you live forever you can keep viewing. >> it's not about us looking pretty. it's about us clicking. >> she's totally right. this is the narcissism of the multi-millionaire ceos of goo e google. >> don't agree with me again. >> i disagree with everything they said. they think they are god. >> they are god now. >> they kind of are god as the other god is dead. >> thank you for that. >> they're already putting all of their money into -- they're trying to live forever. they could care less about us. it's not the 1%. it's those two. >> the funny thing about bill is you discovered immortality, being so disgusting death looks at you and says no thanks. >> even death now. obama hates me. polls. this is somebody that works at google and decided to put that into the press and send that out. there's the 1% in the sky. >> shut up. thank you

dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. we firmly believe that parents out there every child so if it should happen that one child is left without his own parents then other people should turn up and embrace them and treat the child as their own dad i think we're ready to take part in the tour de france they were right on smooth roads run through to france and europe where on siberian roads that means we're better no more noel's. they don't have potholes in the tour de france we do. this team has covered. the cells and kilometer of yes he says you let me out. on the whole of ukraine central russia much the orals and almost all of siberia sort of there but suddenly i was kids who grew up in basements around sewage and heating pipes. today they go around the world with their adoptive parents calling on people not to be a fright but he's obliged to overcome their fears myths stereotypes and prejudices me i just go to the orphanage with you to bring the children out of here m

i'll dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. way firmly believe that parents out there every child so if it should happen that one child is left without his own parents then other people should turn up and embrace them and treat the child as their own dad i think we're ready to take part in the tour de france they right on smooth roads run through to france and europe we're on siberian roads and that means we're better you know mohels. they don't have potholes in the tour de france we do. this team has covered mall. the cells and kilometer of you let me out. on the whole of ukraine central russia the orals and almost all of siberia is one of the about some million homeless kids who grew up in basements around sewage and heating pipes if you look at the last one today they go around the world with their adoptive parents calling on people not to be a fright but is it wise to overcome their fears myths stereotypes and prejudices mean if we just go to the orphanage with you to bri

dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. way firmly believe that parents out there every child so if it should happen that one child is left without his own parents then other people should turn up and embrace them and treat the child as their own dad i think we're ready to take part in the tour de france they right on smooth roads run through to france and europe where on siberian roads that means we're better you know mohels. i don't have potholes in the tour de france we do. this team has covered mall. than ten thousand kilometers yes he says you let me out . on the whole of ukraine central russia much the orals and almost all of siberia sort of there but suddenly i list kids who grew up in basements surround sewage and heating pipes if you look at the last one today they go around the world with their adoptive parents calling on people not to be a fright but he's about to overcome their fears myths stereotypes and prejudices me i just go to the orphanage is to bring th

i think this is great because [bleep] you orphans. you shouldn't have job. >> the sun ain't gonna come out tomorrow. that's just a musical. >> the guy has no parents so how can he be trusted, right? >> that's why batman is such a [bleep] employee at wayne industries. >> we will get letters. >> i wrote down the edit and i wrote down orphans. >> you don't have to bleep orphans. >> i will get your mom involved somewhat in your career in the beauty pageant days, right? >> greg, she is sitting right off camera. thank you so much for letting her beer here today and experience this. >> how did she get that gun in here? >> no, but this is true. this is something about my generation that is true. i graduated high school and went to college and did it on my own. i did miss america on my own and i have been very independent. this is true. but if i can just add another point, we say strong families are a good thing. we want that in this country. it is a very difficult job market. i'm sorry for being serious. it is for people of all ages. some dad

dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. we firmly believe that parents out there every child so if it should happen that one child is left without his own parents then other people should turn up and embrace them and treat the child as their own dad i think we're ready to take part in the tour de france they were right on smooth roads run through to france and europe we're on siberian roads and that means we're better you know mohels. they don't have potholes in the tour de france we do. this team has covered mall. the cells and kilometers of you let me have it out. on the whole of ukraine central russia much the orals and almost all of siberia sort of there but suddenly i was kids who grew up in basements around sewage and heating pipes if you look at the nasa today they go around the world with their adoptive parents calling on people not to be a fright but he's applying to overcome their fears what myths stereotypes and prejudices me i just go to the orphanage with you

dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. we firmly believe that our parents out. russia's foreign minister sergey lavrov is talking about the syrian crisis during an address to students at moscow state university of international relations let's turn and. look at it in perspective. as. well. syria. the intention was to start a military action against these two countries. justified by the fact that. it was alleged that the rock the chemical weapon was sold weapons of mass destruction to these countries but of course these are more complex issues as i said in my opening remarks in. the formation of a more. just world order a. whole world which is based on the wisdom and the values of all civilizations and not just one but these developments are very painful. and. those who. lose. they responded in different ways that you can come to terms with this. something which is granted because you cannot any significant impact over it because the world's developing changing you you ca

"considering the fact i came to iran to serve the orphans, please do not make my children orphans and my wife." he is seeking his freedom. for more on how you can get involved, make sure you visit our website, cbnnews.com. a home-schooling family in germany is back together again. the government took the four children from their parents because they were educated at home, which is illegal in germany. after a hearing thursday, the kids were temporarily returned to their parents. the vunderlicks have agreed to send their children to public school. mike donnelly of the home defense education system says this is not a victory for home-schoolers. >> this is a victory for a totalatarian regime that is bent on dictating to parents what they can do and can't do when educating their children. the family is great to have their children home, but they should never have been taken. we are very concerned about germany's behavior in this area. >> wendy: a hearing will be held in december to decide if the family will be given permanent custody of their children. actor kirk cameron releases a new doc

her heart for the children living in poverty in africa, where every 15 seconds a child becomes an orphan. you and clayton were high school sweethearts in a sense. ellen: yes, we were. allie: and he knew you were passionate about this the whole entire time, but he didn't necessarily feel like it was his calling. ellen: right. allie: so, how did you convince him to finally head on over to zambia. ellen: yeah, you know, it was so cool to be able to grow up together, because while i was chasing this dream and had kind of this nagging passion to go to africa, he had this dream of playing baseball, and he was going to do whatever it took to get there. so, in some sense, he kind of understood exactly where i was coming from. allie: it was at the urging of ellen that the cy young award winner made his first trip to africa, where they met a little girl who changed their lives. allie: there have been a lot of kids who have pulled a lot of emotions out of you and who you wanted to help. ellen: yeah, yeah. allie: but there's one in particular, and it was a little girl named hope. ellen: yeah, you kn

dream can be summed up in just a few words russia and the world with no orphans. we don't want any children to wake up in orphanages. way firmly believe that parents out there every child so if it should happen that one child is left without his own parents then other people should turn up and embrace them and treat the child as their own dad i think we're ready to take part in the tour de france they right on smooth roads run through to france and europe where on siberian roads that means we're better you know mohels. they don't have potholes in the tour de france we do. this team has covered mall. cells and kilometers yes he says you let me ask about. the whole of ukraine central russia much the orals and almost all of siberia sort of the. homeless kids who grow up in basements surround sewage and heating pipes if you look at the last time today they go around the world with their adoptive parents calling on people not to be a fright but he's applying to overcome their fears what myths stereotypes and prejudices me i just go to the orphanage is to bring the chil

.  >> they serve abused, abandoned, homeless, orphaned and disadvantaged male youth. they're now getting ready to celebrate changing 20 years of young lives. joining us this morning is the founding executive director of ho our house. thank you for joining us this morning. 20 years of celebrating, how exciting is that for you? >> extremely exciting. we never thought it would happen, but it sure did. >> you've been changing lives all those years. i know over 300 young men have walked through the doors of our house. >> oh, yes. >> tell me the age ranges and how do they get there? >> the ages are 16 to 21 years old. they come from state workers, juvenile workers of the juvenile justice system. >> what is the benefit? >> it's their home. they learn an education. they get job training. they get life skills. and they get counseling. >> and i know they come from the entire d.c. metro area, maryland included. and though you're situated near omni, they come from various other places. you're on a 140-acre farmland that oprah helped by in 2000. >> sure did. >> tell me about the b

kevin pickle has known binky ever since the day he arrived. >> binky was an orphaned polar bear from the north slope. >> despite his cuddly name and cute, furry face, this polar bear is a carnivore and doesn't take kindly to strangers. dr. larry was taking a leisurely stroll with his camera. >> i was just walking through the zoo on a lovely warm july day. >> suddenly cries for help pierce the air. >> oh, my god. >> all of a sudden from a distance, i heard terrible, terrible screams. >> dr. rayford rushes with the camera rolling toward the blood-curdling sounds coming from the polar bare cage. >> katherine warberg, an australian tourist, decided to get a picture. >> the 29-year-old woman from sydney, australia, is trying to get a good photo to share with friends back home. >> and katherine climbed over two fences to get up to the polar bear fence, which he could reach through, so once catherine climbed over that second fence, he jumped up and grabbed her. >> binky gets the jump on his unwitting victim. his long arms stretch through the eight-inch space between the bars. the massive be

if you are a ravens orioles orphan you probably have seen this man out at the games and rallies, he is the baltimore bird man. >> he is also charged with sexually abusing a minor. we just spoke to police . >> reporter: disturbing story. a so-called super fan said he is devastated by this news today. the baltimore bird man now facing a charge of sexual abuse of a minor. baltimore county police say the victim is a member of his family. we do have some video of him from one of his events dressed as the bird man. this was back in december of 2011, one of the classic cars they would drive. he appeared at charity events around the area. he worked for the baltimore county fire department. he retired as a captain back in 2008. county police say that last month a member of his family came forward and told detectives that he had sexually abused the victim adding that the abuse went on from 2005 up through 2008. we are told the victim is now older than 18. last flight he gave up to county baltimore police and is charged. they don't know if anymore victims and they say they don't have any evidence

comfortable life, but she fled to turkey after her home was bombed, her husband killed,er this children orphaned i made this tent to shelter us. the other day it rained. we got absolutely drenched. >> reporter: here for a month now, the four-year-old has a fever but there's no medical care for him, and no warm clothes as winter approaches. the 2,000 syrians now call this park home. as the un general assembly debates the state of syria, these people wait in squaller, surrounded by human extrament and the stench of urine. the closest toilet in a mosque a mile away, and the only water source a tap nearby. the message to the international community is simple, help whichever way possible, because their choice cannot be death in their home towns or life in these kinds of conditions. >> reporter: this man was an accountant in the military, his wife an engineer, they abandoned their existence for this. >> military helicopters dropped 400-pound tnt bombs. the children were in constant fear. >> reporter: their old life destroyed. their new reality destitute. >> translator: it's fine here for now, but once

nagaul and orphaned at #. he hopes to went office as a member of the social democratic party. >> another campaign bus in another city for another candidate. >> it is election time but this candidate is one-of-a-kind. he's black. he hold as doctorate in chemistry was beaten up for his skin color years ago and much of the former east germany racism runs higher than elsewhere. that's not stopping him from meeting voters here. quite the opposite. >> they have not identified the potential of immigrants using their experiences from different back ground and they could enrich the political process. >> nationwide only 4% of candidates running for parliament are of immigrant background. 20% of the population is from immigrant stock. the proportion of minority representation here is far below that in france and great britain for example. part of the problem is a german law allowing many to give up citisenship of their original country in order to vote and many don't want to do that. another problem, germans with old tra

considering the fact i came to iran to serve the orphans, please do not let them make my children orphansd my wife without a guardian. >> basically, he's accused of proselytizin proselytizing. you deny that and he denies that but how hard has this year been for you? it must be just awful. >> yes. actually, he wasn't accused of that. his charge was undermining the iranian government. the basis for the charge was christian gatherings. >> i'm sorry. i was simplifying. >> it has been a very difficult year. my daughter just celebrated her seventh birthday and this is the second year without him. and she says how many more birthdays, mom. i don't know what to tell her. it's been very emotional. it's been a lonely road for all of us. i have been traveling, mostly my kids have been with people, different people taking care of them, especially my parents have helped, and you know, it's been a very emotional, very trying time, especially for them. they're 7 and 5 and they don't understand that -- >> he was sentenced to eight years in prison? >> yes. which the thought of it is horrible. we don't kno

the first sank ware foy orphan pigmy elephants is opening.or animals fast losing their natural habitat but funded by the very industry which activists is causing harm to wildlife and the environment. andrew thomas has this report from borneo. >> reporter: take away the people and she's alone. so far the only pigmy elephant at the malaysia first sanctuary. the expectation is there will be 50 injured elephants joining miss rock oh, company for her, but that demand is a worrying sign to the wildlife. the center was officially opened by a government minister, but it's mainly money from the palm oil industry paying for it. the very industry some accuse are doing more to damage wildlife than any other. you are the main sponsor of this problem. your involvement part i've guilty conscience? >> definitely not. what we have done is that we are -- there is a realization that we cannot live in isolation, i think it's a realization that we should be part of the overall effort. >> reporter: it is still possible to see striking wildlife down the river, thou

. >> when he died, he leapt 1,100 acres to widows and orphans, and his children that truck. they comprise the woods, sherwood forest, forestville. it was a contentious thing. it took about 13, 15 years in public. >> this is actually in golden gate park, the casino. it was a controversy at the time to have a place that serve liquor and had card games in golden gate park. eventually, it moved to 24th ave. >> we still have the newly recently refurbished stop along the great highway. the beach shall i -- chalet. i always find it ironic that these federal highway funds were used to refurbish this place for drivers to get a drink. terrific. [laughter] >> there were farms, and there were dairies, as these houses are starting to be built, and they are more conventional residents is, and they are still a farm. in the distance, you can see it is still sand dunes. >> and water once again from windmills and wells. >> there is a few small lakes. some of the lakes are natural lakes. they are not all man-made. >> it took a while to get the water lines out there. >> you can see the huge san

they orphan have to spend a ton of money to pay attorneys as well as immigration fees. not only does our federal government have enormous backlogs when it comes to immigration applications, but it's a very daunting process and this is why as the mayor said, it is so important that we get immigration reform done. in the mid 1990sst i actually worked for the u.s. senate. the last time they passed a so-called immigration reform bill. ~ that immigration bill was a punitive bill. it essentially sent the message to the world that america was not open to immigrants. we need a different message, and this is the message that we need to get out today from san francisco. fast forward to 2010, i was proud at that time to ask mayor gavin newsom to spend a couple hundred thousand dollars to make sure we counted all members of our san francisco community. and who did we ask to step up to make sure that money was well spent? it was then our city administrator now mayor ed lee, adrian and folks behind us who made sure we were counting everyone who was a resident regardless of their citi

brian was essentially an orphan. aids, it takes away so many parents there, and then these children have to go live in horrible situations because that's the only option that they have. every day brian's aunt would leave the house to try to go make money for the family. she was basically going to the city dump to forage for things, whether it was to sell them or for the family to eat. but brian would sit alone every day in the house by himself while she was out trying to make money. i just can't imagine what a mother would be going through to feel, you know, what she would feel like to have to leave her child like that, but it's life or death. so we realized that brian's situation was, it was desperate and we needed to act right then. he was so sick, so we took him to the hospital and the hospital staff did everything they could for a couple of weeks . . . but he didn't make it. brian died. there are so many children just like brian, who died. and the solution to this problem is as simple as food. this is the sad rea

he was born in sen dal and orphaned when he was seven. for 20 years he's been a member of germany.orter: another campaign bus in another german city for another candidate. it's election time. but this social democratic dan is one of a kind, he's black. he holds a doctorate in chemistry, was beat be up for his skin color years ago. in much of the former east germany racism runs higher than elsewhere. but that's not stopping him from meeting the voters. quite the opposite. >> cultural openness in our society is in its infant state we are a developing country in this regard regard, polight tics identify the potential of immigrants and the experiences of their background that could really enrich the political process. >> reporter: nationwide only around 4% of the candidates running for parliament are of immigrant background but around 20% of the population is of immigrant stock. so the proportion of minority representation in is far below that in the parliament of france or great britain, for example. part of the problem is a german law which requires immigrants to give up the citizens

her husband killed, her children orphaned. >> i tied the two blankets i brought with me and made thist to shelter us. the other day it rained. we gotta be salutely drenched. >> reporter: here if a month now, her four-year-old has a fever but there is no medical care for him and no warm clothes as winter approaches. there are 2,000 syrians who now call this park home. they came here hoping for a place in the ref gentlemen camp but there is no room. camps already hold twice as many pimas they are supposed to. and as the u.n. general assembly debates the state of syria, these people wait in squalor surrounded by human ex-ca. and the stench of urine, the closest toilet a mile away, the only water a tap on the street corner. the majority of merely do not know much about critical proposals or diplomatic negotiation buzz their message to the community is simple. help, their choice cannot be death in their hometowns or life in these kind of conditions. he was an accountants in the military his wife an engineer, they abandoned their middle classic citizens for this. >> helicopters dropped tnt