. >> the rosy periwinkle, a plant found in nascar, revolutionized the treatment for hodgkin's lymphoma. was found inant the marquetry of and design -- amazon rain forest. morphine was isolated from the opium poppy. aspirin was synthesized from compounds found the part of the white willow and from the plant, but this week. >> today, a first-line treatment we have for malaria, one of the world's biggest killers, is that on a plant from china is currently our best hope for a controlling this tremendous disease. >> if you look at all the new drugs approved by the u.s. food and drug administration between 1981 and 2006, almost two-thirds of those would have had their origins in nature, not in our lab. what's more interesting is that oftentimes, nature gives us molecule's that may not make it fully through fda trials, but teach us a tremendous amount about how our bodies work in helping disease. inre is a drug used patients and used on coronary artery stance. these are little mesh tubes that get put into the blood vessels and supply the heart with oxygen. they are put in after a heart attack

periwinkle if you will. a frost advisory. around the bay area and the coast. temperatures in the 30s for these areas down to 32 degrees. this lasts until about 9:00 this morning. unless the national weather service decides to cancel sooner. and taking a look at the numbers, some of us, many of us actually warmer than where we started yesterday. and it has to do with the wind. but first we start with the numbers 49 degrees at this hour in santa rosa. 48 in nevada. 46 in fairfield. as we get closer to sunrise, low 40s in oakland. 48 in san francisco. 36 in redwood city. winds keeping numbers up. 7 in fairfield. 11 in concord. around the bay, not as large of a number but sfo by 7:00. by 2:00 in hayward. i'll have a look at what you can expect for the weekend and the next shot of rain coming into the bay area. >>> we have a problem on 680 southbound. there's a fatal accident, unfortunately. southbound 680 near levorna road. it happened at 2:45 in the morning. traffic is not effected so much because it's light. but we want to let you know it's there. they're waitin

the periwinkles are hugely helpful. >> reporter: periwinkles, the emotive lines to the side. >> good. >> reporter: did you try different kinds of eyes? >> we did, yeah. we actually tried at one point 3d eyes. we all were horrified. >> reporter: perhaps the biggest challenge is that schulz never planned for the characters to be seen in three dimension. >> we built a character -- if we built a character that worked at all angles, it didn't look faithful to charlie brown. we built specific head poses for the angle that he drew them at. >> reporter: six poses to be exact. >> ooh! >> we have a profile left, sparky left, sparky right, profile right, up when they yell, and then looking down like when he's riding. that's it. snoopy is the most complicated character we have ever built here at blue sky. >> it's like animating picasso really. >> it is. >> reporter: for director steve martino and his team, having charles schulz's son and grandson as writers on the film made staying true to the characters easier. schulz's son was particularly influential for this scene -- >> craig schulz is a pil

. >> reporter: periwinkles are those emotive lines to the side. you try different kinds of eyes. >> yes. we did. we all were just horrified. >> reporter: he never planned for these peanuts characters to be seen in three dimension. >> we built very specific head poses for the angles we drew them at. we want to feel like, oh, we're all buttoned up and together. charlie brown lays it all out there, but we get to celebrate timeless honesty and never gives up spirit he always has. >> reporter: he's still love bli insecure, even in spectacular 3d. cnn, connecticut. >>> looking forward to seeing that. >>> tracking a lot of thunder and lightning in san francisco. headed over marin. we'll be tracking that after the break. >>> if you're not seeing heavy rain right now, you will be shortly. >> you've got your hands full. lots of hotspots. >> yes 101 and 280. just messed up the ride into san francisco. >> the added benefit of the roadway. just in time for the commute. >> yeah. great timing, isn't it. >>> live radar imagery. look at the lightning. the green is