phillip grant is an assistant professor in infectious diseases at stanford and leads the johnsonen john vaccine study at stanford. thank you, dr. grant. >> good afternoon. >> there are a few different ingut ther 72,66%. 85%. break down what's what. >> right, so the overall prevention against severe disease is in the mid-80s, like you said. one other piece of information that you didn't say, so just -- in terms of what people know, it's an virus vector single dose and these are comparing the efficacy of the please bo vespers the active drug. in the individuals with the active drug it prevented 72% of overall infections and prevented 88% of severe infections studywide. another piece of information that's important, is -- after 28 days of the vaccine there was no people that had been given the real vaccine that ended up in the hospital or died. and substantially, you know, a fair number in the place bo arm. it was effective against preventing against severe disease. but not as effective of mild disease. you also mentioned the lower percentages are efficacy in different regions. >> yeah, 57

phillip grant is leading a stanford clinical trial on the vaccine and noted this looks more like the vaccines we are used to. >> this would be something that would be like most vaccines are given in the united states. >> reporter: a single dose that wouldn't require special handling or deep cold storage, and an advantage in getting shots into arms quickly. >> i think by far the most important thing is to prevent one's self from getting seriously ill from covid, ending up in the hospital or worse. and this vaccine is very effective at that. >> reporter: the company says current trials show it was 72% effective against moderate and severe covid-19 infections in the u.s. compared to efficacy rates in the 90% range for pfizer and moderna, but medical experts say that's more than effective enough, and johnson & johnson's head of pharmaceutical research and development notes the vaccine proved nearly 100% effective in preventing severe cases of the disease. >> even if you were to get covid, some moderate form of covid on our vaccine, what we found is that the data tell us you have a much m

phillip grant has been leading the trial at stanford.& johnson could come early next month. >> then at that point they will be turning in their application, and then with similar timing we may see if it works an approval by, i'd say, mid to late february. >> while dr. grant cautioning the final data isn't in yet, earlier phase two results have been described as promising and earlier this week, dr. anthony fauci says he believes that vaccines from johnson & johnson and astrazeneca will reach review in a matter of weeks. the impact could be significant. the johnson & johnson vaccine does not require any special deep cold refrigeration and experts say the single dose could make it easier to distribute. >> it is easier to say we have the supply here, we can give it to you. versus we have the supply here, what will be here in three weeks. it makes that management much more straightforward. >> johnson & johnson used a similar platform to fight a recent ebola vaccine in africa, something like a four wheel drive of vaccines. now the hope is it w

phillip grant led stanford's study of the vaccine and had this analysis. >> it's about what people would probably expect, about 3/4 protective against infection, but not quite as potent as -- kind of where people were quite surprised how effective the moderna and pfizer vaccines were against infections. >> all right. so joining us now to talk more about this is abc7 news special aren't dr. alok patel. dr. patel, good to see you again. let's get right to the efficacy. there are a lot of numbers floating out there. on the surface it looks like it's lower than the other two, moderna and pfizer. but let's dive in a little more deeply and break that down. >> totally, because you're correct. on the surface people are seeing this headline, 66% effective overall. 72% united states. but people need to understand this is based on a global study of 44,000 people. and that 72% effectiveness is the united states. you have 66% in latin america and lower number, 57% in south africa. but an important number is that 85% of severe cases were prevented. so it's 85% efficacious at preventing those hospitali

phillipe djegal spoke with business owners who say that money from the city could surely help. >>back in october crystal philbrook and her sister stephanie applied for and received a $5,000 grant from the city of antioch to help their business rivertown sweet stay above water and did some help for supplies. not a whole lot now state restrictions on food establishments have only become more strict what we need is. the grants that we don't have to pay them back to help the businesses. >>and they we need to open up we need to be able to have more people come out a recent survey among small business owners conducted by the antioch chamber of commerce shows financial assistance would be more helpful. >>then reduced restrictions and that up to 21% of those businesses may have to close permanently because of a drastic loss in revenue rivertown chest co owner debbie blazers says her shop has seen a profit loss of 25% stating it's been tough without foot traffic that sir that's our goal that's our bread and butter retailer more in goods and adds the city should also invest in its own infrastructure like into the downtown into the retail spaces because. >>that that's part of it here and

phillipe djegal spoke with business owners who say money from the city. >>could help them. >>back in october crystal philbrook and her sister stephanie applied for and received a $5,000 grant help for supplies. not a whole lot now state restrictions on food establishments have only become more strict what we need is. >>the grants that we don't have to pay them back to help the businesses and they we need to open up we need to be able to have more people come out a recent survey among small business owners conducted by the antioch chamber of commerce shows financial assistance would be more helpful. >>then reduced restrictions and that up to 21% of those businesses may have to close permanently because of a drastic loss in revenue rivertown chest co owner debbie blazers says her shop has seen a profit loss of 25% stating it's been tough without foot traffic that sir that's our goal that's our bread and butter retailer more in goods and adds the city should also invest in its own infrastructure like into the downtown into the retail spaces because. >>that that's part of it here and that matters as heirloom arthur says the city has about 40 million dollars in reserves and wan