director for institute of neurodegenertive diseases and has written a new memoir, the discovery of preon, the principal of disease which reveals his dramatic journey from pariah to profit. he challenge everything that the scientific community thought they knew about path owe generals leading the way for that matter which eventually might become a breakthrough for treatments like alzheimer's, parkinson's and other forms of dement dementia. we owe you a thank you for your persistence when they told you were wrong. >> thank you. >> i want to get to your work about preons and what the hope is for fighting cures for these illnesses and diseases in a moment. but your book fascinating. it's really an interesting sort of inside account of the fact that scientific breakthrough can be both collaborative but also pretty cutthroat. i'm not sure that the uninformed, the uninitiate like me knew how cutthroat this can be. >> well, i think cutthroat may not be the perfect word to describe this. i think that people in science work very hard. and they have a problem. their problem that only one person, on