roche expired the patents for three drugs, lucrative ones.ou talked about the -- that six medicines have already been approved by regulators a lot of times these new med since take a while to gain trust. how do you think revenues will be as a result of these patents expiring >> first of all, we hope that we will be able not to see any kind of decline, but being able to see stable and even slight growth perspective in the next years to come. this is only possible because we have seen something we have not seen in our 120-year history six new treatments have been approv approved, and we see these treatments have come fast to patients when we look at last year, already 50% of our growth have come from these new medicines. that's a positive signal and is creating confidence for future of the company >> no question we're seeing a shift in pharmaceuticals, and a question of whether amazon could enter the space. last year they applied for pharmacy licenses. are you in the camp that thinks amazon will make an entry into pharmaceuticals? if so, how di

roche closed the year with an m&a deal.s thected, but roche ending last trading day of the year, announcing the acquisition of the u.s. biotech. nothing of russian size, but it got people excited again and we have the big health care conference that jpmorgan holds next week and everyone is deals, etc. you will continue to see cherub pharma among large small biotech's, but in terms of wholesale m&a, that will still end up being dependent on assets and specific needs of the pharma companies. science coming more in focus. sam: entirely. volatility is so much that two weeks later, what i write is irrelevant. whattrength of the euro is we need to keep an eye on. 1.22 ther is back at euro and it is one we need to think about when it comes to the euro reporting companies. it is important for the u.s. as they suffered from the strength of the dollar, now it has weakened and helped them. we saw that in q3 and i expected in q4 too. guy: we will look forward to that jpmorgan conference. senior pharmaceutical analyst sam fazeli, thank

roche has the most out of companies. interest of patients, it is allowing us to to these new medicines patients faster and quicker. >> will be set here last year we spent time talking about drug pricing because candidate trump talked about drug pricing. president trump has a knot. the pressure is still here. where are you feeling it most? struck pricing is an important topic and it is important in the context of the entire health care span. we are part of the solution to overall health care costs. hemophilia,cine for which is groundbreaking, has shown a reduction in hemophilia patients in terms of believes they have. a more convenient dosing regimen. once a week, once every two weeks, and ejection they can give themselves versus iv infusions. certainly it is a benefit for .he health care ofi am not accusing you pricing your drugs too high. what i'm wondering is, in this ,nvironment, also in europe where are feeling pricing pressure the most? >> pricing pressure has been part of our business for decades. >> is it worse? >

ford china sales fell 4.4% last year overall higher by 0.4% >>> roche wins a breakthrough for the labelutuomati aut. >>> google alpha bed unit bit u. >>> and deutsche bank plans to hike payments the $2.2 billion the german newspaper reports the news comes amid concerns another year of low benefits could push bankers to defect to more generous rivals deutsche bank 6.6% in german trade >>> futures down as much as 70 points on the dow at the start and now down 70 points 2% gains in each of these three indices. good morning >> good morning. >> last week 2% gains. every week, exactly. and all 11 of the s&p sectors were high are. year to date, month to date, 9 out of 11 higher it's incredibly broad is that something that concerns you? >> look, i think we had a step function up in expectations. i think part of this has been a really good forecast season out of the united states building up from 11% gains and that's happening before we actually had the impact of tax cuts in states what you see a little bit this morning you see pressure both bond and stock markets the one thing that sticks out o

it was created by the deputy of gregory roche and convince had several levels of access until the summer of twenty sixteen it was possible to change any of the data that the world agency coincide with this back and twenty third see it cannot serve as evidence i've mentioned scratches and marks on sample bottles arguably the most solid proof that however was never shown to the public just like the visual results of the bottle flaw experiments back to the water's mysterious additional data that amounts to intelligence extracted from its whistleblower program and other sources many people in russia would like to know who these sources are and why they should be trusted one more segment additional intelligence provided by the international winter federations i'll tell you what the association that unites these federation said the i.o.c. our request to clarify what's going on some federation official seem to have been racking their brains while the president of the international biathlon union was particularly outspoken it is very sad there is no direct proof of should pull into guilt the i.b

on wall street, 2018 brings key data that could move stocks in astrazeneca and roche. finally, a return to m&a. investors hope 2018 sees corporate tax reform, spurring acquisition of biotech companies, marking a turnaround from a relatively slow 2017. for "nightly business rep meg terrell. >>> your house is likely your biggest asset. so we asked diana olick to tell us what's ahead for real estate. >> reporter: 2017 saw a big slowdown in the housing market. not in prices, but in home sales, because there was just nothing to buy. 2018 will not be much better. sales slow more. sales could become even more sluggish as the supply situation worsens. yes, homebuilders will continue to increase activity. that could squeeze would-be buyers to the sidelines. all that demand without much supply will keep the heat on home prices and affordability will become a bigger issue, especially now that the republican tax plan wipes out valuable d prope taxes and mortgage interest in high cost areas. mortgage reform. the biggest move in 2018 could be in the mortgage market. and the elephait

the times columnist david aaronovitch, the author, thomas kielinger of germany's die welt, and marc roche london correspondent of le monde, who now writes for the magazine le point. welcome to you all. let's discuss france and britain, first. emmanuel macron came on his first official visit to britain this week. among the agreements reached between the french president and british prime minister? theresa may committed to spending an extra £41; million on border security in calais. france said they would lend us the bayeux tapestry in a few years‘ time. with brexit inevitably the backdrop to this meeting, mr macron said the two countries were making a new tapestry together. see what he did there? marc — what did you make of this meeting, a new "entente cordiale"? how did you read it? well, the bayeux tapestry, you give a big gift for love, they say, french and a small gift forfriendship. it symbolised this meeting, better military cooperation, better arrangement on calais. and fights against terrorism. the background was brexit. president macron was very clear. the usual british tactic is

the times columnist david aaronovitch, the author, thomas kielinger of germany's die welt, and marc roche let's discuss france and britain, first. emmanuel macron came on his first official visit to britain this week. among the agreements reached between the french president and british prime minister? theresa may committed to spending an extra £44 million on border security in calais. france said they would lend us the bayeux tapestry in a few years' time. with brexit inevitably the backdrop to this meeting, mr macron said the two countries were making a new tapestry together. marc, is this the new "entente cordiale"? see what he did there? what

kuala lumpur but it'll be around the site there's a bit of a gap before you pick up the next lot of roche's through indonesia including catching jakarta. nothing much moving means the air it's all layers throughout india so the north indian plane in particular we've still got cold nights persistent fog and poor quality is better to the south. the weather sponsored by qatar and greece. education with a different. interpretation of his law is absolutely different from mine as a muslim woman a taliban school for girls in afghanistan reveals a way of life rarely seen. your goal to not only tell them about their bills and regulations let's not let you keep. an exclusive documentary gains access to the goals of the taliban. at this time on al-jazeera. i listen to the top stories here at al-jazeera hawaii's governors apologize for an accidental alert warning of an imminent ballistic missile attack that triggered panic among locals who scrambled to find shelter the measures the management agency later confirmed it was a false alarm and that an investigation is underway the government has pledged se

ella realize that just nut and ferrero roche a isn't cutting it in the u.s. vonnie: it's getting rid of some of these unhealthy items. shery: kick cats are fine -- kit kats are fine. vonnie: another milestone for u.s. stocks. the s&p topped 2800 earlier. holland & cow, chairman, michael holland. know about ge? -- michael:too late much too late. has a tough road ahead. i said enough is enough. would you get back in at some point? michael: sure. it will be desperate prices. it's likely over the next 12 months that the company will be broken up. year, 16%urns last underperforming against the s&p 500. would this be the right time to buy it? investor butas an someone who is speculating on the possibility of a breakup and having some of the parts being worth more than what is trading at today. vonnie: why hasn't it been broken up? ge has faced major problems in some of its units. why not break up already? michael: mr. flannery could answer that question. i can't because i'm not there. --ry: aside from ge michael: really good news. shery: this rally continues. it wi

revenue san oy fit cites a $10 million market, but investors worried about increasing competition fr roche acquired juno for about $9 billion at celgene spend $93 in to 2015 to acquire about 10% of the company it brings personalize the cancer therapies to market. that it will bring in $3 billion po peak annual sales, so they've had open season for m & :, with lots of big companies and older -- and of course there's a wealth of biotech targets valued between $2 billion and $10 million. >> meg, thank you. meg tirrell back at headquarters. >>> there's been plenty of talk about deals to come, so we thought we would ask our players to play matchmaker here. who do they think would make the perfect match? grasso >> the market tells you more often than not where the target will be. bluebird has been out there a as a potential takeoff target i think i'm going to say pfizer blue democrat bird is the next one, and i think it's gilead that takes them out. look at gilead, and 12 sometimes multiple >> is celgene a partner? would they be an obstacle? >> i don't think so. >> guy >> me or dan at t tesaro h

paul's evangelical booth every lutheran church celebrating 150th year but it will be roche one rememberedtunning news. it's long-time pastor david jost is gone under a cloud. >> i just think it's sad. i mean it's just like it's this domino effect that's happening all over. >> reporter: fox 29 has learned parishioners were called to meeting by letter sunday with a church bishop in a recording obtained by fox 29 bishop tracy bartholomew spoke o the gathering. >> a number of weeks ago i was called by an individual with a credible complaint that your pastor engaged in an inappropriate relationship with an adult married woman who is member of this congregation who's not his wife. >> reporter: she says she conducted her own probe and learned more. >> i received additional rewards ranging from unwanted advances to other inappropriate behavior on the part of the pastor. >> reporter: on the phone with fox 29, bishop bartholomew says jost admitted to some of the behavior he resign as of januar. a woman approached the door at jost's lumberton home but wouldn't open it bishop says no laws have been b

roche, novartis is there this morning. then banks with hsbc and lloyds.t the minors and oils, so royal dutch shell, rio tinto on that side of the ledger. looking at the losers, bank send barclays on the downside. deutsche's number 10 as far as that, so not a huge drop this morning. we just don't see a lot of losers compared to winners today. even though we don't see a lot of action as far as size in the market, you do see more gainers than losers this morning. stocks around the world continue to hit fresh news high -- new highs. a pullback on the s&p lasted all of one day yesterday. even a one-day pullback we saw. three hours, and the nikkei closed at a 16-year high. we have seen 27 year highs out of japan most days of the last couple of weeks. we are seeing real strength across equities worldwide. freddie laitw, . does this make sense to you, this rally? foam?s just a bit of freddie: it is, but that makes sense to me. we have seen it does -- devaluation across the last 10 years and all of these bubbles inflated across the world. one of the cheapest that

roche is a perfect example of how her changing it. we need to be out there looking around saying here are atypical or nonstandard developments out there in the marketplace that we are not see normally through our traditional supply base. we have to be doing both it is a communications layer, of give-and-take. >> it's an 18 month organization. as we talk about capital one of the challenges is how do we adequately fund and invest in commercial technology that may not meet the quarterly earnings impact. the real challenges that our adversaries are not waiting. they recognize this. i'll share some stats. if you look at all venture deals in the united states in 2015, 12% had an investor from china. that's up from 6% in 2010. if you look at certain technology such as robotics 17% of the funding was from china. see you can make determinations of why they're doing it. but if we think they're going to be military relevant in the future, then getting a seat at the table early, prior to our regulatory activities take place, that's a big deal. th

roche down after the cfo said he sees pressure on profitability as the company loses some exclusivityugs. pressure, as is bp, taking a 1.7 billion dollar charge on the deepwater horizon closure. this is fullyys manageable within the existing financial framework, but still a loss on bp, down a little more than 1%. thanks for that. ahead of this weekend's first anniversary of donald trump presidency, republican leaders in washington are said to be weighing a stopgap spending bill extension to february 16. so the government doesn't have to stop -- shutdown at this time. they don't believe they have time to complete a fiscal year this friday'sby deadline. "the washington post" reports the chances of an imminent shutdown under -- are increasing. still with us, luke hickmore. the private and often takes credit for the stock rally. do you think this is a trump rally? do you think what we have seen the s&p do can be attributed to the white house? luke: certainly some of it has to be around the tax cuts, but i think this is momentum that started way back before the election. probably as far ba

ge on the industrial side, roche on the other side, a digital platform in terms of diagnostics.nna, you were talking about those fx moves from the korean won. this is the chinese scenario. i'm talking about the foreign exchange reserves, rising for 11 straight months. january,gle month bar and we were going into anaphylactic shock about what that meant. $129are holding back, billion last year in 2017. and the yuan strengthened against the dollar. this is the world's largest foreign currency stockpile, and it is building momentum. bloomberg economics say they expect a broadly stable 2018. there are still risks of plenty, the rebalancing story, the global trade. we rallied in december by 1.6% alone on the yuan. in terms of what happens next from the pboc, will they go in syncopation with the fed? because they don't want that differential to widen. anna: and what does the global growth from the chinese mean for the reserves as well? and the trade tensions? we will talk about that for the program. a host of great guests to discuss that with. wewill also be hearing more, have an excl

but on roche san that and yom kippur and day of atonement, she went to the synagogue in moscow, and when she came out, thousands upon thousands of jews came out to greet her, to touch her, to call her golda, to give her notes to slip into her pocket to send home somehow to help them. and somebody pushed her into a taxiing cab for her own safety, and all she could think to do was put her head out the cab window and say thank you for having remained jewish. and there were other things that are not so well known. she had complex relationships with all the men whose names you know; ben-gurion, shimon peres, itzhak rah p bean. that whole group were always fighting with each other, and yet there they were, they created the state of israel. when she was labor minister, she became labor minister in 1949, and aside from the laws and legislation about women, she managed to push through also a very progressive insurance law that became the basis of israel's social security system now and their welfare state now. and she worked on housing of the immigrants who came -- [inaudible] very temporary hous

if you look at what nike did with the roche, an $85 shoe that they put in the better channel as a cool shoe and they have done that. it's not price point because like the nmd from adidas is $1 hospital it's all bert when do you that ceo shoe as a performance shoe it doesn't sell well in dick's t.sells well in the right place with the right market is under it and under armour takes much of their marketing and focuses it on performance rather than a broad lifestyle thing. >> pete, we talk about this all the time. >> the valuation level is still scary. even at these level, safe. that's part of the concern are they losing big time in shoes also when you consider what nike is doing and what adidas is doing and where under armour sits in that category and that's something that kevin plank made, a specific point a few years ago and have they made the right he had wear are they doing it actually with their sales of shows >> they have made decisions that haven't been good. the product hats been good but arguably not good new. again, they focus a lot on performance, not on sort of general lifest

they're known for ferrero and roche chocolates.'t like banana dipped in nutella. >> nutella dipped in nutella is the way we eat it in our house. >> or with a spoon. >>> all right. senator cory booker says the president's purported comments hit him hard. wheel talk with the democrats. d keep it off. contrave is believed to work on two areas of the brain: your hunger center... i'm so hungry. (avo) and your reward system... ice cream. french fries. (avo) to help control cravings. one ingredient in contrave may increase suicidal thoughts or actions in some children, teens, and young adults in the first few months. serious side effects are mood changes like depression and mania, seizures increased blood pressure or heart rate, liver damage, glaucoma, allergic reactions and hypoglycemia. not for patients with uncontrolled blood pressure, seizure history, anorexia, bulimia, drug or alcohol withdrawal, on bupropion opioids, maois allergy to the ingredients, or pregnant. may cause nausea, constipation headache, and vomiting. reduce hunger,

roche -- in taking the crown, netflix shoots the lights out in the third quarter and says there is moreme, taking its market cap above $100 billion. daybreak,""bloomberg i am david westin along with lisa abramowicz. lisa: netflix has a bigger capital than amazon. david: did you watch "the crown?" lisa: i did not, but you are helping boost their market capital. , leadings solidly up european indexes. s&p futures down just slightly and nasdaq is up heading into the open. some news about specific companies, j&j up about 2%. they are off the earlier highs, up less than 1% -- 1% after reporting better earnings-per-share. verizon was up about 2%, despite an earnings-per-share miss. tesla was up about 1%. gains, 1.4g on those percent, with signs that elon musk was going to extend his tenure at the helm of this company. he will not get a salary or bonus, just the dream. david: time now for the morning brief. at 10:00, the senate banking hearings on fed nominee marvin goodfriend. at 1:00, president trump signs into law the new duties, and after the bell, continental and united report their earni

tom: four or five years ago, steve wrote -- steve roche, that was amazing at the end of davos a few yearsi cannot wait to see you saying "sweet caroline" at you'd -- like you did last year. francine: andrew barden will be managing the fort in davos with simon kennedy. james, i don't know whether this helps animal spirits at the margins if world leaders find the trump argument about protectionism convincing or if it's a clever way of getting attention off the books -- onto the book onto trump's travel plan. james: i think mr. trump feels he is misrepresented. although america first sounds loud, raucous, opinionated, at the end of the day, he is trying to have a fair deal and ripping up of the trade deal, his repudiation of the paris agreement on climate change are of his perspective of having a fair deal. i think he needs to put this point across more clearly and firmly. i think protectionism is a real risk. i think people have consigned it to the wastepaper basket of history. if you want to develop market economy -- if you are a developed market economy and facing an erosion of jobs by te

expecting a little perhaps at the valuation they're paying here and there is coming competition, too rocheas a new drug, people are worried about that franchise and gene therapy is coming to the states which is a potential cure for hemophilia in a one-time treatment that is a few years off. it's an exciting stage >> is hemophilia so lucrative even though it's rare that the treatments generate more revenue or is it more common than i realize? >> it's pretty common. it's a very expensive disease to treat. >> if you're a hemophiliac, you have to deal with that your whole life, it's like saying, gene therapy, you can cure it, but then you have to live with it 70 years? >> absolutely. these are preventive treatments. people have living with their their whole life people say some are moving in the direction of gene therapy. >> thank you >> thank you >>> coming up thousands of federal workers won't report to work today because of the shutdown but those huddled masses can visit the statue of lipts, cu liberty, courtesy of the state of new york. ahead, we have a look at friday's winners and losers.

they have not at any point breached those sanctions that they signed on to now with all of this with roche he believed that that approach was the best way to bring peace to the korean peninsula. this is gus this further now is joseph chung a political analyst and professor at hong kong city university mr chung welcome to the program it's good to see whether as now i think the key word here has to be timing doesn't it it seems as so as it into korean talks achieved the first breakthroughs don't know china decides to lash out at russia and praise china over north korea as that do you think there's anything deliberate here in the timing of his remarks. this is lastly propaganda work the united states took on news from administration to explain to the americans that the effectiveness of his policy towards the korean peninsula has been handicapped by the lack of support by russia and china but i think to be fair to russia and china they have made it very clear to the united states that they are willing to go along with economic sanctions against north korea but there are limits and both countri

pete: thank you, roche shaw. everybody learned not now. thank you, sir. i is causing flood concerns for homeowners across the kentucky river. >> in danger of losing their concerns as they damaged properties across the river. tell us what we can expect run the country. >> because we've been having this incredible freezes and well-equipped for months. usually you see that a little bit later in the spring when everything finally thought-out. we've had this incredible nice weather this weekend, kind of what we had last weekend. will this time stay a little bit warmer. i think we'll continue to see those ice jams that freezing up anytime soon. showers across florida today. the storm track is out across parts of the west right now with a lot of snow across places that needed. a very dry winter so far. great news for the ski areas the number culture and everything across the southwest. the storm moving across parts of the flames in the pacific northwest as well. one quick thing because of the little warm weather you see across parts of texas. this time of year g