and special working group, a retired dean at stanford and a pediatrician and russ altman to try what the alternatives might be. the design of the children study could in fact take greater advantage, things that have happened more recently particularly the advent of previous technology like electronic health records in ways to do this kind of study which i am totally committed to make sure we invest in in a way that will be more efficient and less costly and the designs that are mostly put together years ago. i take your point that when you talk about longitudinal cohorts studies there are all kinds of ways to stubbier oto and all kinds of ways to be successful. is a good example, we need to learn from those lessons. i think the we are again building and jim greenewood's vision, an exceptional moment where we have for the first time the ability to design such a cohort that taps into electronic health records that are available for many individuals who could then participate which much less trouble in terms of getting information about their medical histories and experiences with healt