sanjay gupta is here to answer them. sanjay ali from marin county, california, asks, will this new painkiller make you loopy like the other meds? i can't take any pain meds because i feel like i'm on another planet. sanjay, what are the potential side effects of this new painkiller? >> yeah. >> so the basic. >> so what we're hearing from the clinical trials, the basic side effects really tend to not be so much an effect on the brain, but rather things more like itching, muscle spasms and and rash. the thing to keep in mind is. that opioids, those medications they typically work on the brain, they are sedating. they can make people feel loopy. they can be addictive, as we well know, this medication, it tends to work more at the site of the pain sort of preventing or at least decreasing those pain signals from getting to the brain. so really a totally different mechanism. >> of how. >> this works. >> jake connie tells us that she suffers from chronic pain syndrome, and wants to know if this drug will treat long term chroni

sanjay gupta is back with some answers for you. thank you for being back, sanjay.so let's jump right into it. stephanie from minnesota submitted this question and asks, how is this new drug any different from other prescription pain medication? and this gets to the crux of why it could be so life changing. >> yeah, i mean, this. >> is a. >> pretty big deal in the world. >> of. >> pain medications because. >> it is essentially. >> representing a totally different class of pain medications. you know, you. >> typically think of. >> anti-inflammatories or opioids or sometimes even things like antidepressants or anti-anxiety medications. this works in a in a very different way. you know, for opioids, for example, the way, you know, the brain is processing all pain. so opioids in many ways work by sort of dulling the sensation of pain in the brain. and that's why people often feel loopy or feel a little off when they're taking opioids. the way that this medication works is actually more at the site of pain, where the pain is initially being processed, and it changes the

sanjay, over to you on that point. like we play this game or we watch people play this game constantly just raising questions. just why could this be happening? i'm not saying anything specifically the facts here. what are they. yeah. >> and just a little bit of the context as well. you know, senator cassidy is a doctor as as manu mentioned, a gastroenterologist who who worked with vaccines, helped set up these nonprofits to administer vaccines, including some of the ones that were a topic of discussion in last week's hearing. so there's there's a huge context for for senator cassidy in his role as a physician. but yeah, this idea that, look, there was a there was a question mark, could vaccines be related to autism? we're talking in the late 90s. this came up from a now debunked paper, but it still came up and it raised people's questions and their concerns. so it was studied that that that's the point that i think senator cassidy was making. last week. you asked for data. well, that data has been collected. and we ta

sanjay gupta joins us now to answer them. hi, sanjay. great to see you as always. so, so much curiosity about this drug. connie tells us that she suffers from chronic pain syndrome and wants to know if this drug will treat long term chronic pain. >> this is. the big question right now. so the approval is for acute pain. >> so think. >> you know, post-operative. pain a broken bone. >> that sort. >> of pain. that's where it seems to to provide the most benefit. and that's where it seems to be potentially a good alternative to opioids. connie, i think in that question also mentioned taking medications like antidepressants, for example. this could potentially provide relief for those sorts of pains. chronic pain is still a little bit of an open question. they did this this trial where they actually looked at the use of this medication called shou zi chew for sciatica. that's back pain with pain that's radiating down the leg. and they found that it did improve pain scores about two points. so if you had a pain level of six, for example, it may have gone to four. so not

sanjay gupta explores how this impact shaped treatment for today's spinal cord injury patients. >> ielt i needed to do something not just for myself, but for everyone else in the same condition. >> our dad pushed himself constantly to be at the cutting. >> edge of what the. >> medical breakthroughs might be. so a big priority for him was getting time off the ventilator. >> christopher reeve. >> could not breathe on his. >> own after a horse riding. >> accident left him paralyzed. >> from the neck. >> down in 1995. in 2003, he underwent an experimental. operation to implant a pacemaker like device. it's something known as a diaphragmatic pacing system, or dps. >> it's electrical. >> signals that cause us. >> to be able to. >> move. and so. we can use stimulation to actually produce a movement. >> instead of a ventilator. the implant stimulates and even strengthens a patient's diaphragm, allowing them to breathe. doctor adelle fields has been researching the use of electrical stimulation on the nervous system for more than three decades. >> diaphragmatic pacing allows them to. >> be. a

sanjay gupta joining us now. okay, so in preparation for you, because you're a brilliant human being and i can just try to do my little research, i saw that the cdc said that in 2021, 20% of u.s. adults deal with chronic pain in this country. that's like 50 million people. it's like an astonishing number. what can you tell us about this new pain medication that is unique compared to others? >> yeah. >> you're exactly. >> right on those numbers. and they're actually increasing at a faster rate than a lot of other. >> diseases. >> including heart. >> disease and diabetes. >> so we. >> are a country, frankly. >> a world in. >> a lot of pain. so this is. >> very welcome news, sara. and big news. the medication we're talking about is suzetrigine. that's what it's called or journavx ax is going to be the trade name um, you know, celebrex was the last medication you were talking about that was approved in 1998. we typically approve dozens of medications every year, but this is the first pain medication. it is pretty uni

sanjay gupta has more in today's chasing life. >> i'm doctor sanjay gupta, host of cnn's chasing life something you may not know. a lot of those cleaning supplies in your house may have some surprising impacts on your health. the nonprofit environmental working group found that more than 2000 cleaning products in the united states might contain chemicals linked to asthma, cancer and chemical burns. now, this doesn't mean you necessarily need to start throwing everything out of your cabinet. but here's a tip next time you need to replace something, spend a minute looking for this. the epa's safer choice label or checking their online database. also, you know, remember that things like vinegar, baking soda, lemon juice, they can also be used for cleaning. and finally regularly vacuuming and cleaning surfaces. that's obviously important not just for dust, but also for removing those toxic chemicals which can build up in that dust. don't overdo it. how much and how often you're exposed matters, so it's important to use products as directed. and you can hear more about how to optimize your

sanjay gupta joins us now. sanjay, what's so unique about this new pain medication?ell, the way. >> that it works is it blocks pain specifically without causing a lot of sedation or euphoria. that's the biggest thing. and as you mentioned, phil, i mean, it's really been since 1998 that we've had a new pain medication that's been approved. fda typically approves dozens of new medications every year, but it's been a long time on on pain medications. when you think about opioids, you just mentioned, the way that they typically work is is really in terms of impact on the brain. specifically, the brain is where all pain in the body is processed. this new medication, called suzetrigine or journavx, acts. it basically changes the way that that pain signal is actually transmitted from the site of pain. so it doesn't it doesn't cause euphoria. it doesn't cause sedation. and hopefully it makes it less addictive as well. so a lot of excitement around this bill. >> yeah, it seems significant. do we have any sense of how big of an impact it could have? >> you know, pain is a is a

sanjay gupta, joins us now. sanjay, what's unique about this new pain medication and how big of an impact could it have? >> yeah, this is a. >> pretty big deal. as you just mentioned. >> it's. >> been since. >> 1998 that there's been a new pain medication approved. i mean, the fda typically approves dozens of medications for all sorts of things, but not pain. so patients really haven't had many options. i think what is unique about this, if you think about opioids that you just mentioned, they tend to work primarily on the brain. the brain processes all pain. so that's why they're sedating. they can cause problems with addiction. these pain medications suzetrigine journavx acts as it's called, works sort of more at the location of the pain, sort of trying to block the signals coming from the source of pain going to the brain. as a result, you shouldn't get euphoria, you shouldn't get the sedating. it should lower the risk of addiction as well. so that's pretty significant. jake, i'll tell you, if you look at the

. >> chasing life with me, doctor sanjay gupta.herever you get your podcasts. >> closed captioning brought to you by book.com. >> if you or a loved one have. >> mesothelioma. >> we'll send you a free book to. answer questions you may have. call now and we'll come. >> to you. >> 800 821 4000. >> birdstrikes are dramatically on the rise. >> a bird. >> the size of a canada goose. an eagle. they can take out an engine or both engines. he had a flock. >> we begin. >> with breaking news. officials now say that nearly everyone on board a plane that crashed in south korea has died. >> december 29th, 2024. >> 181 people. were traveling on the jeju air. passenger jet, which. >> crashed while landing. >> at muan international airport. >> a nearby business owner captured the crash landing on his cell phone. >> you can. >> see the plane skidding across the runway. moments later, the boeing 737 slammed into a nearby embankment and exploded. 179 people died. about five minutes before crashing, the plane hit a flock of ducks. >> the control. >> to

. >> i'm doctor sanjay gupta in atlanta, and this is cnn. >> closed captioning is brought to you by sokolov law. >> mesothelioma victims call now $30 million in trust. money has been set aside. you may be entitled to a portion of that money. call one 800 859 2400. that's one 800 859 2400. >> a critical call with a possible trade war at stake, president trump expected to speak with canada's prime minister at any moment. tariffs set to take effect at midnight. if these two leaders can agree on a deal to prevent that from happening. >> and a warning from an official at usaid. elon musk's threat to shut down the agency is a, quote, apocalypse for a group that provides billions of dollars in desperately needed aid for other countries, the billionaire says trump agrees with him that the agency needs to be closed in a grim salvage operation underway as crews begin to remove large parts of the wreckage of american airlines flight 5342 from the potomac river. officials are giving an update here on the effort. just one hour from now. and we're following these major developing stories and many more, a

sanjay gupta in atlanta, and. this is cnn. >> one week after that deadly mid-air collision over the potomac river, newly released data from ground based radar suggests the army helicopter was higher than it was supposed to be when it collided with the american airlines passenger plane. but the ntsb does want more proof. cnn's pete muntean is live for us at reagan national airport. pete, what more are you learning from the ntsb? >> the ntsb says. >> brianna, no smoking gun. just yet with that new data. no way to. >> say for sure if there. >> is any sort of big conclusion to draw here so far just yet. but the. >> latest information. >> from the ntsb is. >> this radar. >> data that shows that that black hawk helicopter, at. >> least according to radar. >> screens here in the control tower. was being displayed. at 300ft. the altitude restriction on the special helicopter corridor that goes through the airspace here at reagan national airport is limited to 200ft. so again, one big piece of data. >> as more and more. >>

. >> doctor sanjay. gupta wherever you get. >> your podcasts. >> air tragedy strikes. >> again, this. >> time very close to home. i'm michael smerconish here. in philadelphia. >> a medical jet carrying. >> six people crashed into a philly neighborhood, causing a massive explosion that affected nearby homes and vehicles. the small. >> plane was carrying a pediatric patient and her mother. >> along with four crew members, a pilot. >> copilot. >> doctor and medic. at this time, authorities. >> cannot confirm any survivors from the crash were awaiting a news conference. >> perhaps this. >> hour. >> from here in philadelphia. as we. >> get updates. >> we'll bring them. >> to you. >> this all coming. >> after the tragic blackhawk and american airlines collision. >> that killed 67. >> people near reagan. >> national airport on wednesday night. >> a chilling collision above the potomac. >> upended after the consoler in chief pivoted and began. >> playing the blame. >> game and speculating while. providing no evi

sanjay gupta is here to answer your questions about it. plus, the white house

sanjay gupta in atlanta, and this is cnn. >> closed captioning is brought to you by purple. greatest sleep ever invented. >> we've been out of a job. >> that's because purple mattresses are made with patented gel flex grid technology. >> do not go to purple. >> com do not visit a purple store. >> breaking news. one of the architects of project 2025 is now a step closer to joining president trump's cabinet. the senate just now voting to move forward with russell vought. confirmation to run the white house budget office. vought once boasted about trump's involvement in project 2025, captured on at the time, a hidden camera saying this. >> he's been. >> at our organization. he's raised money for our organization. he's blessed it. so he's very supportive of what we do. >> the he being trump and vought making those comments as trump was actually publicly denying any involvement, saying he hadn't read anything about it. manu raju is out front, so, manu, let's just start here. russell vought obviously, obviously so central to that particular project. does it appear he'll be confirm

. >> listen to chasing life with me, doctor sanjay gupta, wherever you get your podcasts. >> we haveome breaking news for you in our money. lead canadian prime minister justin trudeau just said moments ago that the proposed u.s. tariffs on canada are set to go into effect tonight at midnight, are going to be paused for at least 30 days. let's go straight to cnn's kaitlan collins. caitlin, this major update follows a long phone call between trump and trudeau. was this an expected outcome? >> yeah, jake. >> actually. >> two phone calls that happened between. >> president trump. >> and. >> prime minister trudeau. >> one this morning and then one that just happened before this event that he held here at the white house with the hockey winners. >> of this year of the stanley cup. >> and moments before. he entered. >> the. >> room for that event. this was when he had this conversation with prime minister trudeau. and the big question going into that was whether or not trump was also going to pause the tariffs that were set to go into effect at midnight tonight against canada, 25%. i should

doctor sanjay. gupta wherever. >> you. >> get your podcasts. >> breaking news.earning the fbi has handed over information of 5000 employees to the justice department, to the senior members of the justice department. trump's appointees, multiple these agents and analysts were all in some way, shape or form were touched, touched a january 6th case. multiple lawsuits have now been filed to stop the doj from publicly naming these employees, which includes a suit supported by trump's former white house attorney, ty cobb, who joins me now. ty, let me just start, though, with where we are. the macro environment. mass layoffs now coming across the federal government. 5000 employees from the fbi handed over to senior members of the doj. what do you fear is happening in the fbi right now? >> i think what's happening in the fbi. >> is quite a tragedy. >> and unfortunately, the citizens. who depend on the fbi for national security and. important protections. >> are being. >> mistreated and. >> cheated. >> uh, the the agents whose identities and personnel information is bein

. >> i'm doctor sanjay. >> gupta in atlanta, and this is cnn. >> this panic in silicon valley aroundhe new a.i. model from the chinese company deep seek. and the hispanic in many pockets of the world about the potential negative consequences of a.i. but my next guest wants us to remain optimistic about the possibilities of this amazing new technology. tech entrepreneur and co-founder of linkedin, reid hoffman, has a new book out called super agency what could possibly go right with our a.i. future? i should note he's a founder of multiple a.i. ventures. he's also on the board of and an investor in many companies involved in a.i., including microsoft. um, so let me first ask you, deep sea, you and i have chatted you of a slightly different perspective than the one i described. tell me what you you know, what's your basic takeaway from the deep sea? uh, release? >> well, the principal thing, i think, in your excellent article that i agreed with was the fact that constraints do create good innovation opportunities. and that's one of the things that we should all in the world, including

. >> sanjay gupta. >> in atlanta. >> and this. >> is cnn. >> tonight's the night president trump says he will keep his promises to hit some of america's biggest trading partners with aggressive new tariffs. an additional 10% tariff on chinese imports and a 25% tariff on goods coming into america from canada and also from mexico. most economists believe this will lead to higher prices for americans. the wall street journal editorial board, calling it, quote, the dumbest trade war in history. cnn's alayna treene is live in west palm beach, florida, with more on this. and elena, obviously, we're still waiting for more details in all of this. what are you hearing from the white house on details and timing of these tariffs? >> well, as for timing, jessica, i am told that we should expect these tariffs imminently, that the president is expected to sign them at any moment now, back at his resort at mar a lago. behind me on that island, behind me over there. but look, i think his vow to carry through and follow through on his threat to impose steep tariffs on the united states neighbors is no

. >> i'm doctor sanjay gupta in atlanta, and this is cnn. >> tonight. democrats versus elon musk. the texas tech titan may be a shadow president going full bane. the batman villain is what we're talking about here, crediting himself for returning power to the people, while at the same time dismissing any criticism of anything that he is doing, calling all of his opponents cronies of the radical left shadow government. democrats agree that musk is a problem, but listen to them today and they have a pinata in search of a stick to our republican colleagues, if you do not see the light, we will bring the fire. >> resist. we are going to be in your face. we are going to be on your. >> we have days to stop the destruction of our democracy. we have work to do. >> tell elon musk to take his hands off your money. >> we don't pledge allegiance to the creepy 22 year olds working for elon musk. we pledge allegiance to the united states of america. >> and god, shut down the city. we are at war. >> we will win. we will win. we will win. we won't rest. we won't rest. >> i'm greg. congratulations

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. >> doctor sanjay. >> gupta, wherever. >> you get your podcasts dad started regaining elements of movement and they were small but so meaningful. >> that was. >> there in the gym. >> right there swish swish swish. oh, there he goes. >> oh my. >> god! >> oh my god. >> my spirits rose with the possibility that i was on the road to recovery. >> you do have to learn to walk the fine line between hope without expectation. as soon as you start expecting, expecting something, the disappointment is so much more ferocious. >> you know, i think if he could have just gotten off the ventilator. oh my god, he practiced so much. it was. it was brutal to watch. >> but the strength of the muscles weren't present to give him enough ability to wean off completely. >> right. >> he wanted to give people. >> hope. >> but it was really hard. and he did not show that to the world. >> what's really curious is that in all the time since my injury, i have never once had a dream in which i've been in a wheelchair. >> it's easy to sink into a depression and you have to get them out. we had a list of people we'd call