sanjay gupta joins us with details. good evening. thanks for joining us. >>> we begin with the steepest plunge yet for the man whose fall from grace rivals that of anyone in modern memory. 22 years ago, this was rudy giuliani, then mayor of new york and "time" magazine's 2001 person of the year, america's mayor some called him. former crime busting u.s. attorney. looking like a man on top of it. tonight after years of working for and lying for a man he'd likely have prosecuted in his former life, he learned the price to be paid for just a fraction of those lies, namely the ones he told about shaye moss and ruby freeman. two 2020 georgia election workers he defamed again and again, including outside his civil trial earlier this week and again today after the jury awarded moss and freeman $148 million in damages. that includes more than $16 million each for defamation, $20 million each for the emotional distress he caused them by upending their lives, and punitive damages totaling $75 million. >> the flame that giuliani lit with those

sanjay gupta joins us now. this is confusing.at he was receiving ketamine therapy irp, that is separate from the ketamine athat was in his system when he died. >> yeah, that's right. this is just such a sad story but it does sound like he was being treated for depression and anxiety separate from ketamine and then they make a point of saying this was an aacute ketamine something more recent. they later state in this 30 page report there was something trace in his stomach. it can be injected snorted or swallowed. sons like something he had swallowed. when i read the report it made the case if he swallowed it it takes typically half hour to an hour to take in effect, before you have the symptoms associated with ketamine. and at some point he got into the swimming pool while on the ketamine and this disabsorbive effect led to his drowning. >> separate from this therapy he was likely taking ketamine either recreationally or self medicating with ketamine, people can buy it online or with a prescription. that becausese he became disass

sanjay gupta. >>> sandra day o'connor has d died. how the naugs is remembering this trailblazer who made history asas the firstst woman serve onon the u.s. . supreme c. first time i connected with kim, she told me that her husband had passed. and that he took care of all of the internet connected devices in the home. i told her, “i'm here to take care of you.” connecting with kim... made me reconnect with my mom. it's very important to keep loved ones close. we know that creating memories with loved ones brings so much joy to your life. a family trip to the team usa training facility. i don't know how to thank you. i'm here to thank you. >>> she ushered in a new era of the supreme court, inspiring men jen rations of women to join the legal profession. sandra day o'connor passed away today at age of 93. joan joins us now with more. it's hard to overstate the influence that sandra day o'connor had. >> it really is. in the law, for years, we all lived under her influence. especially in abortion rights, it was really felt. but she had a

our own sanjay gupta takes a look back at the top ten health stories of 2023. ♪ ♪ >>> 2023 may best beed as an incredible year of breakthroughs and innovation while also a year of continuing to deal or not deal with basic ongoing health problems. our team has had many moments now to reflect, be inspired, learn and re-double our efforts to help make all of you happier, healthier and more in form. let's kick things off with number ten of our top ten health stories. >> january 2, 2023. the very beginning of the year. buffalo bills safety damar hamlin goes into cardiac arrest on national tv. >> we will need everybody. >> a quick response not only saved hamlin's life, but brought national attention to the importance of cpr, rapid defibrillation and the nfl's safety protocols which i saw firsthand. >> keep in mind the medical team was able to get to damar hamlin within ten seconds and speed really matters here. every additional minute that someone in cardiac goes without cpr mortality goes up by up to 10%. >> number nine, you probably never heard of fennell of rin. it's okay. it's in average

sanjay gupta joins us now. what could be find this and how concerned schapeople be?ll, you have to take the information come out of china with a bit of a grain of salt. i have been reporting on these outbreaks for 20 years, and going back to sars in 2003, this most recent pandemic. you have to try to figure out the story behind the headlines here, which i think is what dr. cohen is referring to. is this a virus spreading between humans? yes. are they spreading within the community? yes. the hospitals are overwhelmed in certain places. the last point is not a novel virus is really important. it's the novel viruses that quickly spiral into pandemics. so it's the swarm of viruses, flu, rsv, covid as she mentioned. by the way, we saw upticks in the winter last year here as well. all of a sudden you sort of see the viruses swarm and a lot of people get sick quickly. one thing that appears to be complicating things, especially in china, is also bacterial infections. they seem to be a large part of whatever is driving this as well, and they have a lot of antibiotic resistan

sanjay gupta is out front with me now. as we are learning more details here, at the time of his death in october, it was determined there were no drugs at matthew perry's house, yet he died of a ketamine overdose. can you tell us more about this drug and the effects of this drug that could have led to his either death and then, you know, drowning effects or his drowning. >> yeah, there were -- it was a long report, erin. it was about 30 pages. as you point out, acute ketamine intoxicate was listed as the primary cause. ketamine that he had taken recently. they found remnants of this trace amounts in his stomach. it sounds like something that he swallowed. you can take ketamine in different ways. it can be injected, snorted, it can be swallowed. if it's swallowed, it takes usually about a half an hour or so for it to take effect. so reading through this report sounds like what happened is that he took some ketamine, he went into the pool, the ketamine is a disassociates someone from their environment. when they measured the

sanjay gupta has a preview. quick warning that some viewers may find parts of this clip disturbing. >> we're trying to locate 26 lost children. >> this is a story that stopped the nation dead in its tracks. july, 1976, a bus full of children on their way home from summer school, held at gunpoint by three masked men, forced into a trailer and then buried underground. the kidnappers hoping to be paid a huge ransom. >> the bus has been found, there are no signs of violence and there are only horrified guesses as to what may have happened. >> ultimately, after 28 hours, somehow they managed to escape, and authorities were quick to say there was, quote, no indication of harm. that was something child psychologist tear did not believe. >> the kids were not okay. somebody got a psychiatrist to come to town, and he made a prediction, he said, one kid in this 26 is going to have a problem. but what happened was that no parent wanted to admit that his kid was the one in 26. by the time i got out there, 100% of those kids

sanjay gupta. a short break. we're back on the other side. >>> turning to sports, a special night in the nba as lebron james took the court against the next generation of talent for the first time. andy scholes joins me now. fans, i believe, had been waiting for this matchup. they had it circled on their calendar for some time. how did it go? >> everyone has been waiting for lebron vs. wembanyama. lebron has been playing in the nba longer than victor has been alive. this is his 21st season. wemby is 19 years old. s this is the first time they squared off. he's 7'4" guarding lebron in the corner here. but lebron skies a three over him. lebron had had had 23 points. the spurs were running 18-game losing streak going into this one, but a slam there. lakers were without three st starters, including anthony davis. i they weren't able to overcome it. 129-115, here's here was wemby afterwards on facing lebron. >> just awe struck. >> like people are when they see you. >> i mean, i would have thought i would feel some typ

man is up and about. >> happy new year and look forward to a lot more in 2024. ♪ >> thanks to sanjay guptat. >>> russia confirmed a warship has been damaged after a ukrainian airstrike. the latest on ukraine's counteroffensive next. >>> the mayor of new york says protests for wars on hamas. more on that ahead. >>> now to ukraine's kherson. 100 civilians packed into a train station waiting to be evacuated came under russian shelling. one was killed, several injured. russia's confirming now this morning damage to one of its naval tank landing ships in the c crimea region. that strike on tuesday after ukraine claimed that it was destroyed by an airstrike. fred pleitgen is live with reporting on both of these fronts. when you look at kherson and how strategically vital that is and you look also at crimea and how important that is, what do we make of the airstrike the third loss of russian military hardware in a week? >> reporter: yeah, the third major loss, russians seem to be taking serious losses recently. also those jets that have been shot down apparently by patriots sur surface-to-air mis

sanjay gupta has taken a look at this autopsy and is here now. sanjay, can you, as a doctor, walk us through what stood out to you, whether this was an overdose from ketamine or what they found from this? >> it's a 30-page report so it's mostly talking about what did not happen, what did not contribute to his death. what they really focused in on was the fact he had ketamine in his body. they found elements of ketamine in his stomach. and they said that that was one of the primary causes, along with the fact that he was in a pool and had drowned. those are the things that really stood out to me. we looked at specifically the dose of ketamine that he had in his blood, and it was pretty high. you can see the numbers there in the 3,000 range. and to give you some context for what that means, ketamine can be used as an anesthetic, kaitlan. and the range can be from 1,000 to 6,000. here's the important thing is that ketamine in and of itself is very rarely associated with someone overdosing and dying, unlike opioids, which is suppresses your ability to

sanjay gupta takes a closer look at the report here. >> sadly, here's what we do know after reading this0-page report from the medical examiner's office, they list acute effects of ketamine as the cause of his death, matthew perry's death, along with drowning. coronary artery disease, and -- to give you some context of the ketamine, the dosing that they found, the levels that they found were around 3,200 nano grams per milliliter. the tell you what that means, sometimes it can be used in anaesthesia and the levels there are seen between 1,000 and 6,000. he had a lot of ketamine in his system. a couple of important points, it is still incredibly rare, even at those levels, for someone to die of ketamine intoxication. unfortunately, he was also in the swimming pool at the time, and it sounds like that in combination with the ketamine is likely what led to his death. as one medical examiner told us, the ketamine probably is not what ended up killing him, but made it more possible for him to drown. that is kind of what we know at this point. they do know that some ketamine was found in his s

sanjay gupta, thank you. >>> thank you for joining me this evening. i'm paula reid.l see you again tomorrow night starting at 4:00 eastern. stay with us for the cnn special "all the best and all the worst: 2023." >>> 2023

sanjay gupta, cnn reporting. >> be sure to tune in, the all new cnn film "chowchilla" premieres sunday at 9:00 p.m. only on cnn. >>> it was a sight to see last night as a strong gio magnetic storm amplified the northern lights. this is incredible video. it captured a beautiful display of the aurora borealis in north dakota. all thanks to the strong level three storm. the space weather prediction center says events like these can brighten the northern lights visibility as far south as pennsylvania, iowa, and also all the way to oregon. but can disrupt radio signals and gps systems. so, if you were lost in the stars last night, you now know why. >>> major cities across the northeast are seeing a record-breaking snow drought this winter. new york, philadelphia, d.c., they've not seen a single inch of snow in more than 600 days. here to discuss our snowless forecast for this part of the country is cnn emergency elise is a rafa. what is going on here? >> this is incredible. new york hasn't had a blockbuster storm in almost two years. 656 consecutive days since new york city has seen more th

sanjay gupta, thank you. appreciate it. >>> coming up what this new phase ofof the israel-l-hamas w looks toninight. stayay with usus. the power goes out and we still have wifi to do our homework. and that's a good thing? great in my book! who are you? no power? no problem. introducing storm-ready wifi. now you can stay reliably connected through power outages with unlimited cellular data and up to 4 hours of battery back-up to keep you online. only from xfinity. home of the xfinity 10g network. >>> welcome to "the lead" i'm jake tapper. this hour actor felicity huffman opening about thought college admissions scandal that land her in the clink. huffman said she was trying to give her daughter a future and she felt like she had to break the law. >>> plus donald trump's attempted defense today pushing to get his criminal case in georgia dismissed arguing the indictment against the former president violates his free speech. >> and

sanjay gupta joins us. so how bad are these vaccination rates right now? >> reporter: we are sort of sleepwalking our way into this season. when you look at the overall numbers, they are concerning. i will show you these, but i preface this by saying we have never been great in this country about vaccination rates, even before the pandemic. flu vaccination was typically below 50%, but it's even lower now. compare last year to this year, for example, for kids and adults the numbers are nowhere. they are too low. if you look at covid, i sort of made this graph for you, pamela, to take a look at since the beginning of vaccines, where we have been and where we are now. you can see on the graphic, that red line there, those are the first shots that came out. a lot of people got those first shots. the blue line are some of the second shots. that is still pretty high. the bottom right of the screen, if you can even see it there, pamela, that's right now. that is the most updated covid shots. fewer than 20% of people in the country have gotten that. and then our i

sanjay gupta. good morning. it is not just one thing. it is not just flu. it is all three of the things together. where are we on vaccinations for all of them? >> yeah. yes, so, sort of this triple threat. as the former cdc director said, we're sort of sleepwalking into this. people are sort of paying attention a little bit, but clearly not enough. take a look at flu, first of all, just compare this year's vaccination rates, compared to last year's vaccination rates. as you look at the numbers, we never have been great about getting a lot of people vaccinated for flu. always been well below 50%. but it dropped off even more this year as compared to last year. that's for kids and for adults. if you look at covid specifically, and we made this graph to show you from the beginning of vaccinations to where we are now, what you find is that initially people were pretty good about getting their initial -- that's the red line at the top, getting the first shot and then even completing the first booster at that point, the first sort of primary series of shots. but

sanjay gupta has more. >> sadly, here's what we know after reading this report from the medical examiner'sice. they list acute effects of ketamine as the cause of death, along with drowning, coronary artery disease . the dozing of the levels that they found were around 3200 than grams per milliliter. sometimes ketamine can be used in anesthesia. typically the levels there are seen between 1,000 and 6,000. he had a lot of ketamine in his system. it is still incredibly rare even at those levels for someone to die of ketamine intoxication. unfortunately, he was also in the swimming ming pool at the t. it sounds like that in combination of ketamine is likely what led to his death. the ketamine probably is not what ended up killing him, but made it more possible for him to drown. that is kind whoof what we know this point. they do know that ketamine was found in his stomach, which suggested he swallowed it. if you swallow it, it can take a half hour to an hour to take effect. it is possible he took this ketamine before it took effect. he was in the swimming pool. the ketamine caused a significa

sanjay gupta has the top health and wellness stories of 2023. >> 2023 may best be described as an incredible year of breakthroughs and invasion and a year of continuing to deal or not deal with basic ongoing health problems. our team has had many moments to reflect, be inspired, learn and redouble our efforts to make all of you happier, healthier and more informed. let's kick things off with number ten of the top ten health stories. >> i don't like how he went down. >> january 2, 2023, the very beginning of the year. buffalo bills' safety demar hamlin goes into cardiac arrest on national tv. >> we're going to need everybody on call. >> a quick response not only saved hamlin's life but brought national attention to the importance of cpr and the nfl's safety protocols that i saw firsthand. the medical team was able to get to hamlin within 10 seconds. speed really matters here. every additional minute someone in cardiac arrest goes without cpr, mortality goes up by up to 10%. >>> number nine. you've probably never heard of fentyl efrin. this year, an fda committee said contrary to popular belie

sanjay gupta, thank you. >>> thank you for joining me this evening. i'm paula reid. i'll see you again tomorrow night starting at 4:00 eastern. stay with us for the cnn special "all the best and all the worst: 2023." >>> 2023 was a year like no other. jeff everyone seemed to be going all in all the time. now it's time to look at the whole crazy year with our guest, laura baron lopez, omar him nottyesses, laura coates, john berman, charlotte wilder, coy wire, and max foster. we're playing for keeps. it's "all the best, all the worst: 2023." >> welcome, i'm tom foreman. it's worth asking how did we get past the last 12 months. many of us hoped it would be easier than recent years, and there were moments of accomplishment, community, and joy. but we were also challenged, divided over issues and often unable to agree even on what we want. and it was wildly apparent where we begin -- with the biggest news stories of the year. ♪ >> the worst big news for many americans started in their pocketbooks. >> the economy this year was an absolute emotional roller coaster. >> unemp

we'l'll have a repeport from dr sanjay gupta. >>> welcome back. vladimir putin speaking to reporters right now, this is a live look at his end of the year news conference. he usually does it every year though he skipped it last year. putin says if ukraine does not stand down and accept russia's term respect term, moscow will have to, coat, so quote, solve it by force. >> caller: even if we agree on certain parameters and by the way during the negotiations on istanbul we agreed but then they through the agreements in to the oven. but we had agreed on them. or there were other possibilities, either to reach an agreement or resolve it by using force. this is what we'll strive for. >> so he skipped it last year after ordering troops in to ukraine. >>> let's go now to sports where we had a wild game in milwaukee last night that included a fight over who got to keep the game ball. andy scholes has the "bleacher report." hi andy. >> good morning. you know, you don't see it very often. game ball is usually a thing in football. in basketball players genera

sanjay gupta. >> reporter: 2023 may best be described as an incredible year of breakthroughs and innovation while also a year of continuing to deal or not deal with basic ongoing health problems. our team has had many moments now to reflect, be inspired, learn and redouble our efforts to help make all of you happier, healthier and more informed. so let's kick it off with number 10 of our top 10 health stories. >> i don't like how he went down. >> reporter: january 2, 2023, the very beginning of the year, buffalo bills safety damar hamlin goes into cardiac arrest on national tv. >> all call, all call. >> reporter: a quick response not only saved hamlin's life, but brought national attention to the importance of cpr, rapid defib ril lags and the nfl safety protocols which i saw firsthand. keep in mind the medical team was able to get to damar hamlin within ten seconds. and speed really matters here. every additional minute that someone in cardiac arrest goes without cpr, mortality goes up by up to 10%. number nine. you've probably never heard of again nil he have africanthe main ingredient in

sanjay gupta is joining us right now. what do you make of this finding? >> it's a sad story. i read through the 30-page report. the headline is exactly what you said. it sounds like matthew perry had taken ketamine. they found trace elements of it in his stomach and he was in a pool. he's a dissociative drug. it can cause people to have difficulties with breathing and stuff. but what seemed to have happened here, he became -- he drowned. they said it's probably not the ketamine specifically that led to his death, but made it possible for him to drown, wolf. >> and we're told that -- >> just a sad story. >> very sad. we're told that perry was taking ketamine for depression, right? >> yeah. yes, he was. but i think that reading the report, this was a little bit unrelated to that. he was getting infusions of ketamine, but the last time he had received that was a week and a half earlier. to give you context, wolf, the half life is a few hours. it can be a legitimate therapy for depression and anxiety, but this was not related to that. it sounds like he was taking it as well on hi

sanjay gupta has the top ten health and wellness stories of 2023. ♪ >> reporter: 2023 may best be describedan incredible year of breakthroughs and innovation, while also being a year of continuing to deal or not deal with basic health problems. our team has had time to reflect, inspire, learn, and re-double our efforts to help make you happier, healthier. let's kick things off with number ten of our top ten health stories. >> i don't like how he went down. >> reporter: january 2nd, 2023, the very beginning of the year. buffalo bills safety damar hamlin goes into cardiac arrest on national tv. >> all call, all call. >> reporter: a quick response not only saved hamlin's life but brought national attention to the importance of cpr and rapid def defibrillation. the medical team was able to get to damar hamlin within seconds, and speed really matters here. every additional minute that someone in cardiac arrest goes without cpr, mortality goes up by up to 10%. number nine, you've probably never heard of the ingredient in many allergy and cold medicines like vic sinex. this year the fda said it wa

sanjay gupta is looking into it. the cdc sending out this call right now, an urgent need, they say.re do the numbers stand on vaccination rates? >> well, they're not great. we are sort of sleepwalking into respiratory virus season here. if you start by looking at flu overall and compare it to last year to give you some idea, vaccination rates for flu have never been great, typically below 50% or adults but even lower this year, sort of in the mid-30s for kids and adults. if you look at covid, i sort of have made a graph for you that shows you since the beginning of vaccination what's happened. the red line was people who got the first shot, a lot. blue line, people who got the follow-up shots, but the bottom right corner there, that's the updated vaccine, kate, and it's less than 20% have gotten that so far, and then rsv, first time this has been a vaccine that's available. it's recommended for people 60 and older and there again, kate, fewer than 16% of people have gotten that shot, so, you know, i think that's what's prompted the cdc to release this alert. >> the vaccination rate

sanjay gupta joins us now. are these all connected? why is this happening? >> this is amazing.f you look at just the number of prescriptions that have gone out there, it's skyrocketed. these drugs have only been around a few. look at what happened the past few years. close to 2% of the population of this country has been prescribed this medication at some point. that's shocking. i mean, these are huge. obviously, even around the world this is prescribed a lot. as you prescribe more and more, you are not surprised to get more and more sort of accidental poisonings, overdoses, things like that. i want to show you something else important here. you see the numbers go up. in march, 2022, all the shortages started happening. what happened? pharmacies started making their own. they started making their own compounded versions that were not tested for safety and efficacy and you saw the poisoning rates go up as well. so that may be a part of this. i think a lot has do -- i don't know how many of you have seen the ozempic pen. this is it. you open it up, put a needle on there and then